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Delusion of pregnancy : The role of prolactin

Published online by Cambridge University Press:  01 September 2022

R. Jomli ,
H. Jemli ,
H. Ghabi ,
Y. Zgueb ,
U. Ouali  and
A. Aissa
R. Jomli*
Affiliation:
Razi Hospital, Psychiatry A, manouba, Tunisia
H. Jemli
Affiliation:
university of tunis elmanar, Faculty Of Medicine Of Tunis, manouba, Tunisia
H. Ghabi
Affiliation:
university of tunis elmanar, Faculty Of Medicine Of Tunis, manouba, Tunisia
Y. Zgueb
Affiliation:
Razi Hospital, Psychiatry A, manouba, Tunisia
U. Ouali
Affiliation:
Razi Hospital, Psychiatry A, manouba, Tunisia
A. Aissa
Affiliation:
Razi Hospital, Psychiatry A, manouba, Tunisia
*
*Corresponding author.

Abstract

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Introduction

A delusion of pregnancy is defined as a fixed false belief that one is pregnant in the absence of any evidence to support the pregnant state. Different mechanisms have been advanced to explain this phenomenon.

Objectives

Herein, we present a case of hyperprolactinemia with delusion of pregnancy during the use of Amisulpride.

Methods

Herein, we present a case of hyperprolactinemia with delusion of pregnancy during the use of Amisulpride.

Results

This case concerns a 39-year-old, divorced Tunisian woman with the diagnosis of schizoaffective disorder,She has never been pregnant. She was taking Amisulpride at the dose of 400 mg per day with 100mg of Haldol Decanoate. In June 2021, she was admitted to our department as she expressed the thought that she was pregnant. No other psychotic symptoms were reported. There was no history of alcohol or illicit drug use. The physical examination was normal. The blood pregnancy test was negative. A measure of serum prolactin was performed and revealed a high prolactin level at 700 ng/ml. Amisulpride was discontinued. We then recorded the serum prolactin level at one month and then at three months after we stopped Amisulpride. We found that as her prolactin levels decreased her complaint of pregnancy also diminished. Actually, the patient has a normal level of prolactin and has no pregnancy delusion.

Conclusions

Clinicians should be aware that delusion of pregnancy in psychotic patients may be caused by side effects of the treatment. Monitoring of serum prolactin levels in patients under Amisulpride may help to improve the management of these patients.

Disclosure

No significant relationships.

Keywords

schizophréniadelusionPregnancyprolactine
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S706
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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