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CS06.04 - Neuropsychiatric Symptoms (BPSD) in severe dementia

Published online by Cambridge University Press:  16 April 2020

E.J. Byrne*
Affiliation:
Division of Psychiatry, University of Manchester, Manchester, UK

Abstract

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There is no generally accepted definition of Severe Dementia. The current evidence suggests that this stage of the dementia syndrome may have clinically relevant sub-divisions.

There is evidence to support the influence of the severity of dementia on neuro-psychiatric symptoms (either singly or in symptom “Clusters”).The frequency,type and impact of BPSD also change with the severity of Dementia (probably irrespective of aetiology).

The measurement of BPSD in severe dementia also poses challenges; Are the “Gold standard” measures (such as the NPI) appropriate in this stage?; Are stage specific measures of BPSD valid & reliable?; Do such measures encompass the range of symptomatology found in Severe Dementia?

How can we measure BPSD in Clinical Trials in Severe Dementia?

This paper will review the current “ State of the art” in BPSD in Severe Dementia, drawing on collaborative studies from the European Alzheimer Disease Consortium (EADC).

Type
Core Symposium: Integrated approach for the treatment of neuropsychiatric symptoms in the elderly
Copyright
Copyright © European Psychiatric Association 2008
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