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Correlation between psychotic risk and depressive “cognitive” symptoms in adolescence

Published online by Cambridge University Press:  01 September 2022

A. Maffucci ,
S. Cesario ,
V. Mammarella ,
G. Colafrancesco ,
M. Ferrara ,
A. Raballo  and
E. Monducci
A. Maffucci*
Affiliation:
Sapienza University of Rome, Department Of Human Neuroscience, Section Of Child And Adolescent Neuropsychiatry, Rome, Italy
S. Cesario
Affiliation:
Sapienza University of Rome, Department Of Human Neuroscience, Section Of Child And Adolescent Neuropsychiatry, Rome, Italy
V. Mammarella
Affiliation:
Sapienza University of Rome, Department Of Human Neuroscience, Section Of Child And Adolescent Neuropsychiatry, Rome, Italy
G. Colafrancesco
Affiliation:
Sapienza University of Rome, Department Of Human Neuroscience, Section Of Child And Adolescent Neuropsychiatry, Rome, Italy
M. Ferrara
Affiliation:
Sapienza University of Rome, Department Of Human Neuroscience, Section Of Child And Adolescent Neuropsychiatry, Rome, Italy
A. Raballo
Affiliation:
Università degli Studi di Perugia, Faculty Of Medicine, Perugia, Italy
E. Monducci
Affiliation:
Sapienza University of Rome, Department Of Human Neuroscience, Section Of Child And Adolescent Neuropsychiatry, Rome, Italy
*
*Corresponding author.

Abstract

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Introduction

Prevention of disorders has become a central element of psychiatric research and clinic. Currently, Ultra High Risk (UHR) criteria are internationally recognized for psychiatric risk assessment. Self Disorders (SD) aroused particular interest because they were found to be specific to schizophrenic spectrum disorders and a marker of vulnerability for psychotic onset.

Objectives

To evaluate the correlation between psychotic risk and depressive symptoms in at-risk adolescent population.

Methods

We collected data from 80 patients, aged 14-18, with sufficient skills in the Italian language and an IQ ≥70, excluding patients with disorders related to direct effects of a general medical condition or substance. Psychodiagnostic evaluation included K-SADS-PL, SIPS/SOPS, EASE (for the assessment of SDs) and the CDSS (for the assessment of Depression).

Results

35 subjects have UHR criteria, while 45 do not have a psychotic risk syndrome or psychotic features. Between the two groups there is a significant difference in the total SCORE of EASE, in domains 1, 2 and 5. In addition, a positive correlation between SDs and depressive symptoms emerged, in particular with pathological guilt and with reference ideas of guilt.

Conclusions

The results confirm the validity of SDs for early detection of psychosis. Depressive features appear to be associated with the presence of abnormalities of experience. This results suggest a close care and monitoring of depressive symptoms in adolescence, because they can mask disorders of different nature, particularly pathological guilt and guilty ideas of reference that are depressive “cognitive” symptoms more correlate with psychotic risk.

Disclosure

No significant relationships.

Keywords

Self DisordersUltra High Riskpsychosis preventiondepressive symptoms
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S681
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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