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comparisation of ABO blood groups between female patiens diagnosed with depressive disorders an bipolar affective disorders

Published online by Cambridge University Press:  01 September 2022

S. Vuk Pisk ,
K. Matic ,
E. Ivezic ,
N. Geres  and
I. Filipcic
S. Vuk Pisk*
Affiliation:
Clinical Psychiatric hospital Sveti Ivan, Department Of Integrative Psychiatry, Zagreb, Croatia
K. Matic
Affiliation:
Clinical Psychiatric hospital Sveti Ivan, Acute Womens Ward, Zagreb, Croatia
E. Ivezic
Affiliation:
Clinical Psychiatric hospital Sveti Ivan, Department Of Integrative Psychiatry, Zagreb, Croatia
N. Geres
Affiliation:
Clinical Psychiatric hospital Sveti Ivan, Department Of Integrative Psychiatry, Zagreb, Croatia
I. Filipcic
Affiliation:
Psychiatric Clinic “Sveti Ivan”, Psychiatry, Zagreb, Croatia
*
*Corresponding author.

Abstract

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Introduction

The prevalence of ABO alleles in population is different. Many studies confirmed the correlation between the occurrences of some diseases with different genotypes of ABO blood groups. Studies had shown possible differencese between patients with depressive dissorder and bipolar affective disorders according to ABO blood groups. There are contradictory results; some studies had shown significant association between blood group O and BAP, other showed relationship between unipolar depression and blood type O. Others shoedn association between involuntary depression and blood group A and negative association between blood group A and BAP.

Objectives

The purpose of this study was to reassess the potential diferences between patients with depressive dissorder and bipolar affective disorders according to ABO blood groups.

Methods

A total of 97 adult female psychiatric inpatients participated in this study. 57,7% were diagnosed with depressive disorder and 42,3% were diagnosed with bipolar affective disorder. Type of ABO group were measured from the blood samples taken in the morning after 30 min rest. From whole blood, genomic DNA was isolated on QIAcube device (Qiagen, Germany) using QIAamp DNA Blood mini QIAcube kit (Qiagen, Germany). ABO genotyping on 5 basic ABO alleles was performed using allele-specific PCR.

Results

Comparing ABO blood groups between female patients who are suffering from depressive disorders and bipolar affective disorders, we didn’t found any differences. In both examination groups, higher proportion of A blood group was significant.

Conclusions

The results of this study didn’t support the hypothesis of diferences in ABO blood group between depressive disorders and bipolar affective disorders.

Disclosure

No significant relationships.

Keywords

ABO blood groupdepressive disorderbipolar affective dissorderfemale
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S851
Creative Commons
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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