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Clozapine effectiveness in a psychiatric service in Italy

Published online by Cambridge University Press:  16 April 2020

D Berardi ,
M Troia ,
M Dell'Atti ,
C Bartoletti ,
C Cantaroni  and
G Ferrari
D Berardi
Affiliation:
University of Bologna, Department of Psychiatry, ‘P Ottonello’, Viale C Pepoli, 5, 40123, Bologna
M Troia
Affiliation:
University of Bologna, Department of Psychiatry, ‘P Ottonello’, Viale C Pepoli, 5, 40123, Bologna
M Dell'Atti
Affiliation:
University of Bologna, Department of Psychiatry, ‘P Ottonello’, Viale C Pepoli, 5, 40123, Bologna
C Bartoletti
Affiliation:
Mental Health Service ‘Villa Olimpia’, AWL Bologna, Italy
C Cantaroni
Affiliation:
University of Bologna, Department of Psychiatry, ‘P Ottonello’, Viale C Pepoli, 5, 40123, Bologna
G Ferrari
Affiliation:
University of Bologna, Department of Psychiatry, ‘P Ottonello’, Viale C Pepoli, 5, 40123, Bologna
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Summary

Clozapine was administered to 28 resistant schizophrenics at psychiatric services in Bologna. At 26 weeks 62% responded. Positive and negative symptoms improved, but decrease of negative symptoms partially depended upon improvement of positive and EPS. No cases of agranulocytosis were seen. Some drop-outs were related to difficulties with psychopathological improvement.

Keywords

clozapineeffectivenesspsychiatric servicesclinicalschizophreniatreatment-resistance
Type
Short communication
Information
European Psychiatry , Volume 13 , Issue 6 , September 1998 , pp. 317 - 319
Copyright
Copyright © Elsevier, Paris 1998

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