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Clinical evaluation of Major Depressive Disorder (MDD) and Borderline Personality Disorder(BPD) in youth adolescents

Published online by Cambridge University Press:  01 September 2022

V. Kaleda ,
E. Krylova ,
A. Kuleshov  and
A. Beburishvili
V. Kaleda*
Affiliation:
FSBSI «Mental Health Research Centre», Department Of Youth Psychiatry, Moscow, Russian Federation
E. Krylova
Affiliation:
FSBSI «Mental Health Research Centre», Department Of Youth Psychiatry, Moscow, Russian Federation
A. Kuleshov
Affiliation:
FSBSI «Mental Health Research Centre», Department Of Youth Psychiatry, Moscow, Russian Federation
A. Beburishvili
Affiliation:
FSBSI «Mental Health Research Centre», Department Of Youth Psychiatry, Moscow, Russian Federation
*
*Corresponding author.

Abstract

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Introduction

According to international studies, at least 70% of BPD in adolescence are comorbid with MDD.

Objectives

To determine the clinical and psychopathological markers of MDD in BPD in adolescence.

Methods

Clinical psychopathological interview, SCID-II, Hamilton Depression Rating Scale (HDRS). Sample: N=73 male and female, age: 18-25 with MDD and BPD.

Results

MDD comorbid with BPD in adolescence is characterized by polymorphism of its’ psychopathological manifestations due to the structure of BPD and the input of the age factor. In the studied sample 31 (42,5%) with both MDD and BPD also revealed addictions; 24 patients (32,9%) - anxiety and obsessive-compulsive (OCD) disorders, 18 patients (24,7%) had overvalued ideas. The high contingency of MDD with autoaggressive actions confirmed their high suicidal risk (53 patients). Among them - 31 patients (58,5%) - had non-suicidal self-harm (NSSI), 7 patients – (13,2%) had suicidal attempt (SA), and 15 patients (28,3%) had NSSI and suicidal attempts (NSSI+SA). The highest incidence of NSSI and NSSI+SA was noted in MDD with addictive disorders: NSSI – N=20 (80,00%), NSSI+SA - N=5 (20,00%), SA – N=0. MDD with BPD and anxiety disorders: NSSI – N=9 (56,25%), NSSI+SA – N= 6 (37,50%), SA–N=1 (6,25%). MDD with BPD and overvalued ideas: NSSI – N=2 (16,67%), NSSI +SA – N= 4 (33,33%), SA N=6 (50,0%), (results p<0.01).

Conclusions

Psychopathological relations between BPD and MDD in youth are different due to additional comorbid conditions, like addictions, anxiety and OCD, overvalued ideas and have clinical implications in terms of suicidal and NSSI risks, individualized interventions and prognosis.

Disclosure

No significant relationships.

Keywords

major depressive disordernonsuicidal self-injurysuicidal behaviourborderline personality disorder
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S328
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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