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Atypical sensory profiles as core features of adult ADHD, irrespective of autistic symptoms

Published online by Cambridge University Press:  23 March 2020

D. Bijlenga ,
J.Y.M. Tjon-Ka-Jie ,
F. Schuijers  and
J.J.S. Kooij
D. Bijlenga*
Affiliation:
PsyQ Psycho-Medical Programs, Expertise Center Adult ADHD, Carel Reinierszkade 197, 2593 HRThe Hague, The Netherlands
J.Y.M. Tjon-Ka-Jie
Affiliation:
PsyQ Psycho-Medical Programs, Expertise Center Adult ADHD, Carel Reinierszkade 197, 2593 HRThe Hague, The Netherlands
F. Schuijers
Affiliation:
PsyQ Psycho-Medical Programs, Expertise Center Adult ADHD, Carel Reinierszkade 197, 2593 HRThe Hague, The Netherlands
J.J.S. Kooij
Affiliation:
PsyQ Psycho-Medical Programs, Expertise Center Adult ADHD, Carel Reinierszkade 197, 2593 HRThe Hague, The Netherlands
*
*Corresponding author. Tel.: +31 883573076; fax: +31 883584205. E-mail address:[email protected] (D. Bijlenga).
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Abstract

Background:

Abnormal sensory sensitivity is a feature of autism-spectrum disorder (ASD), but is also reported in attention-deficit/hyperactivity disorder (ADHD). In many cases, ADHD and ASD are comorbid. This study investigated the prevalence of sensory hyper- and hyposensitivity among adults with ADHD, controlling for autistic symptoms.

Method:

One hundred and sixteen adults diagnosed with ADHD completed the Adolescent/Adult Sensory Profile-NL (AASP-NL) and the Autism-spectrum Quotient (AQ) questionnaires. Prevalences of hyper- and hyposensitivity and autism-spectrum symptoms were compared to norm values. Multivariate binary logistic regressions were used to determine the association of autistic symptoms, age, gender, ADHD subtype, self-reported severity of ADHD symptoms, comorbid disorders, and use of medication on the sensory hypo- and hypersensitivity in adults with ADHD.

Results:

Adults with ADHD had more autistic symptoms, and they had both more hyper- and hyposensitivity compared to norm groups. This was especially apparent in the Activity level and Auditory sensory modalities. Sensory hypo- and hypersensitivity were both related to an increased ADHD score, even showing a dose-response relationship, but not to any autistic symptom or comorbid disorder. As much as 43% of the females with ADHD reported sensory hypo- and/or hypersensitivity, compared to 22% of the men.

Conclusions:

Sensory hypo- and hypersensitivity may be viewed as key features of adult ADHD, especially in females, regardless of any autistic symptoms. Future research should be directed at the implications of this sensory dysregulation for the understanding of the pathophysiology of (female) ADHD, and on the usefulness of assessment of atypical sensory profiles in the diagnostic procedure of ADHD in adults.

Keywords

Attention-deficit/hyperactivity disorder (ADHD)AutismPsychometry and assessments in psychiatry
Type
Original article
Information
European Psychiatry , Volume 43 , June 2017 , pp. 51 - 57
Copyright
Copyright © European Psychiatric Association 2017

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References

Biederman, JAttention-deficit/hyperactivity disorder: a life-span perspective. J Clin Psychiatry 1998;59: 4–16.Google ScholarPubMed
Spencer, TJBiederman, JMick, EAttention-deficit/hyperactivity disorder: diagnosis, lifespan, comorbidities, and neurobiology. Ambul Pediatr 2007;7: 73–81.CrossRefGoogle ScholarPubMed
Fayyad, Jde Graaf, RKessler, RAlonso, JAngermeyer, MDemyttenaere, Ket al.Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder. Br J Psychiatry 2007;190: 402–429.CrossRefGoogle ScholarPubMed
Garcia, CBau, CSilva, KCallegari-Jacques, SSalgado, CFischer, Aet al.The burdened life of adults with ADHD: impairment beyond comorbidity. Eur Psychiatry 2012;27: 309–313.CrossRefGoogle ScholarPubMed
Kooij, JJBijlenga, DThe circadian rhythm in adult attention-deficit/hyperactivity disorder: current state of affairs. Exp Rev Neurother 2013;13: 1107–1116.CrossRefGoogle ScholarPubMed
Antshel, KMZhang-James, YFaraone, SVThe comorbidity of ADHD and autism spectrum disorder. Expert Rev 2013;13: 1117–1128.Google ScholarPubMed
Reiersen, AMTodd, RDCo-occurrence of ADHD and autism spectrum disorders: phenomenology and treatment. Expert Rev Neurother 2008;8: 657–669.CrossRefGoogle ScholarPubMed
Kochhar, PBatty, MJLiddle, EBGroom, MJScerif, GLiddle, PFet al.Autistic spectrum disorder traits in children with attention deficit hyperactivity disorder. Child Care Health Dev 2011;37: 103–110.CrossRefGoogle ScholarPubMed
Johnston, KDittner, ABramham, JMurphy, CKnight, ARussell, AAttention deficit hyperactivity disorder symptoms in adults with autism spectrum disorders. Autism Res 2013;6: 225–236.CrossRefGoogle ScholarPubMed
Gillberg, ICHelles, ABillstedt, EGillberg, CBoys with Asperger syndrome grow up: psychiatric and neurodevelopmental disorders 20 years after initial diagnosis. J Autism Dev Disord 2016;46: 74–82.CrossRefGoogle ScholarPubMed
Goldstein, SSchwebach, AJThe comorbidity of pervasive developmental disorder and attention deficit hyperactivity disorder: results of a retrospective chart review. J Autism Dev Disord 2004;34: 329–339.CrossRefGoogle ScholarPubMed
Polderman, TJHoekstra, RAPosthuma, DLarsson, HThe co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins. Transl Psychiatry 2014;4:e435.CrossRefGoogle ScholarPubMed
American Psychiatric Association, Diagnostic and statistical manual of mental disorders (DSM-5), 5th ed., Washington DC: American Psychiatric Association; 2013.CrossRefGoogle Scholar
Craig, FLamanna, ALMargari, FMatera, ESimone, MMargari, LOverlap between autism spectrum disorders and attention deficit hyperactivity disorder: searching for distinctive/common clinical features. Autism Res 2015;8: 328–337.CrossRefGoogle ScholarPubMed
Matson, JLRieske, RDWilliams, LWThe relationship between autism spectrum disorders and attention-deficit/hyperactivity disorder: an overview. Res Dev Disabil 2013;34: 2475–2484.CrossRefGoogle ScholarPubMed
Brieber, SNeufang, SBruning, NKamp-Becker, IRemschmidt, HHerpertz-Dahlmann, Bet al.Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder. J Child Psychol Psychiatry. 2007;48: 1251–1258.CrossRefGoogle ScholarPubMed
Ronald, ASimonoff, EKuntsi, JAsherson, PPlomin, REvidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample. J Child Psychol Psychiatry 2008;49: 535–542.CrossRefGoogle Scholar
Rommelse, NNFranke, BGeurts, HMHartman, CABuitelaar, JKShared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder. Eur Child Adolesc Psychiatry 2010;19: 281–295.CrossRefGoogle ScholarPubMed
Reiersen, AMConstantino, JNVolk, HETodd, RDAutistic traits in a population-based ADHD twin sample. J Child Psychol Psychiatry 2007;48: 464–472.CrossRefGoogle Scholar
Taurines, RSchwenck, CWesterwald, ESachse, MSiniatchkin, MFreitag, CADHD and autism: differential diagnosis or overlapping traits? A selective review. Atten Defic Hyperact Disord 2012;4: 115–139.CrossRefGoogle ScholarPubMed
Lundstrom, SChang, ZKerekes, NGumpert, CHRastam, MGillberg, Cet al.Autistic-like traits and their association with mental health problems in two nationwide twin cohorts of children and adults. Psychol Med 2011;41: 2423–2433.CrossRefGoogle ScholarPubMed
Baron-Cohen, SAshwin, EAshwin, CTavassoli, TChakrabarti, BTalent in autism: hyper-systemizing, hyper-attention to detail and sensory hypersensitivity. Philos Trans R Soc Lond B Biol Sci 2009;364: 1377–1383.CrossRefGoogle ScholarPubMed
Robertson, AESimmons, DRThe relationship between sensory sensitivity and autistic traits in the general population. J Autism Dev Disord 2013;43: 775–784.CrossRefGoogle ScholarPubMed
Micoulaud-Franchi, JALopez, RVaillant, FRichieri, REl-Kaim, ABioulac, Set al.Perceptual abnormalities related to sensory gating deficit are core symptoms in adults with ADHD. Psychiatry Res 2015;230: 357–363.CrossRefGoogle ScholarPubMed
Kooij, JJAeckerlin, LPBuitelaar, JKFunctioning, comorbidity and treatment of 141 adults with attention deficit hyperactivity disorder (ADHD) at a psychiatric outpatients’ department [Dutch]. Ned Tijdschr Geneeskd 2001;145: 1498–1501.Google Scholar
Treister, REisenberg, EDemeter, NPud, DAlterations in pain response are partially reversed by methylphenidate (Ritalin) in adults with attention deficit hyperactivity disorder (ADHD). Pain Pract 2015;15: 4–11.CrossRefGoogle Scholar
Ghanizadeh, ASensory processing problems in children with ADHD, a systematic review. Psychiatry Investig 2011;8: 89–94.CrossRefGoogle ScholarPubMed
Romanos, MRenner, TJSchecklmann, MHummel, BRoos, Mvon Mering, Cet al.Improved odor sensitivity in attention-deficit/hyperactivity disorder. Biol Psychiatry 2008;64: 938–940.CrossRefGoogle ScholarPubMed
Kooij, JJAdult ADHD: diagnostic assessment and treatment, 3rd ed., London: Springer; 2013.CrossRefGoogle Scholar
Sheehan, DVLecrubier, YSheehan, KHAmorim, PJanavs, JWeiller, Eet al.The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998;59(Suppl. 20):22–33.Google ScholarPubMed
van Vliet, IMde Beurs, E[The MINI-International Neuropsychiatric Interview. A brief structured diagnostic psychiatric interview for DSM-IV en ICD-10 psychiatric disorders]. Tijdschr Psychiatr 2007;49: 393–397.Google Scholar
Lord, CRutter, MLe Couteur, AAutism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 1994;24: 659–685.CrossRefGoogle ScholarPubMed
Kooij, JJBuitelaar, JKvan den Oord, EJFurer, JWRijnders, CAHodiamont, PPInternal and external validity of attention-deficit hyperactivity disorder in a population-based sample of adults. Psychol Med 2005;35: 817–827.CrossRefGoogle Scholar
Szomlaiski, NDyrborg, JRasmussen, HSchumann, TKoch, SVBilenberg, NValidity and clinical feasibility of the ADHD rating scale (ADHD-RS) A Danish Nationwide Multicenter Study. Acta Paediatr 2009;98: 397–402.CrossRefGoogle ScholarPubMed
Dopfner, MSteinhausen, HCCoghill, DDalsgaard, SPoole, LRalston, SJet al.Cross-cultural reliability and validity of ADHD assessed by the ADHD rating scale in a pan-European study. Eur Child Adolesc Psychiatry 2006;15(Suppl. 1):I46–I55.CrossRefGoogle Scholar
Brown, CEDunn, WAdolescents/Adults Sensory Profile-NL: Manual [Dutch] USA: NCS Pearson; 2007.Google Scholar
Dunn, WThe impact of processiing abilities on the daily lives of young children and their families: a conceptual model. Infant Young Child 1997;9: 23–35.CrossRefGoogle Scholar
Brown, CTollefson, NDunn, WCromwell, RFilion, DThe Adult Sensory Profile: measuring patterns of sensory processing. Am J Occup Ther 2001;55: 75–82.CrossRefGoogle ScholarPubMed
Baron-Cohen, SWheelwright, SSkinner, RMartin, JClubley, EThe autism-spectrum quotient (AQ): evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. J Autism Dev Disord 2001;31: 5–17.CrossRefGoogle ScholarPubMed
Hoekstra, RABartels, MCath, DCBoomsma, DIFactor structure, reliability and criterion validity of the Autism-Spectrum Quotient (AQ): a study in Dutch population and patient groups. J Autism Dev Disord 2008;38: 1555–1566.CrossRefGoogle ScholarPubMed
Woodbury-Smith, MRRobinson, JWheelwright, SBaron-Cohen, SScreening adults for Asperger Syndrome using the AQ: a preliminary study of its diagnostic validity in clinical practice. J Autism Dev Disord 2005;35: 331–335.CrossRefGoogle ScholarPubMed
Edvinsson, DLindstrom, EBingefors, KLewander, TEkselius, LGender differences of axis I and II comorbidity in subjects diagnosed with attention-deficit hyperactivity disorder as adults. Acta Neuropsychiatrica 2013;25: 165–174.Google ScholarPubMed
Dunn, WBennett, DPatterns of sensory processing in children with attention deficit hyperactivity disorder. Occup Ther J Res 2002;22: 4–15.Google Scholar
Mangeot, SDMiller, LJMcIntosh, DNMcGrath-Clarke, JSimon, JHagerman, RJet al.Sensory modulation dysfunction in children with attention-deficit- hyperactivity disorder. Dev Med Child Neurol 2001;43: 399–406.CrossRefGoogle ScholarPubMed
Chen, CXiu, DMoyzis, RXia, MHe, YXue, Get al.Regional homogeneity of resting-state brain activity suppresses the effect of dopamine-related genes on sensory processing sensitivity. PLoS One 2015;10:e0133143.CrossRefGoogle ScholarPubMed
Wu, JXiao, HSun, HZou, LZhu, LQRole of dopamine receptors in ADHD: a systematic meta-analysis. Mol Neurobiol 2012;45: 605–620.CrossRefGoogle ScholarPubMed
Dixon, EABenham, GSturgeon, JAMackey, SJohnson, KAYounger, JDevelopment of the Sensory Hypersensitivity Scale (SHS): a self-report tool for assessing sensitivity to sensory stimuli. J Behav Med 2016;39: 537–550.CrossRefGoogle ScholarPubMed
Broring, TRommelse, NSergeant, JScherder, ESex differences in tactile defensiveness in children with ADHD and their siblings. Dev Med Child Neurol 2008;50: 129–133.CrossRefGoogle ScholarPubMed
Merwin, RMMoskovich, AAWagner, HRRitschel, LACraighead, LWZucker, NLEmotion regulation difficulties in anorexia nervosa: Relationship to self-perceived sensory sensitivity. Cogn Emot 2013;27: 441–452.CrossRefGoogle ScholarPubMed
Brown, CCromwell, RLFilion, DDunn, WTollefson, NSensory processing in schizophrenia: missing and avoiding information. Schizophr Res 2002;55: 187–195.CrossRefGoogle ScholarPubMed
Yochman, AAlon-Beery, OSribman, AParush, SDifferential diagnosis of sensory modulation disorder (SMD) and attention deficit hyperactivity disorder (ADHD): participation, sensation, and attention. Front Hum Neurosci 2013;7:862.CrossRefGoogle ScholarPubMed
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