Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-17T07:24:19.329Z Has data issue: false hasContentIssue false
  • English
  • Français

The association between the Lie scale of the Maudsley personality inventory and striatal dopamine D2/D3 receptor availability of healthy Chinese community subjects

Published online by Cambridge University Press:  16 April 2020

Chieh Liang Huang ,
Yen Kuang Yang ,
Ching Lin Chu ,
I Hui Lee ,
Tzung Lieh Yeh ,
Po See Chen  and
Nan Tsing Chiu
Chieh Liang Huang
Affiliation:
Department of Psychiatry, China Medical University and Hospital, Taichung, Taiwan, ROC
Yen Kuang Yang*
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
Ching Lin Chu
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
I Hui Lee
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
Tzung Lieh Yeh
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
Po See Chen
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
Nan Tsing Chiu
Affiliation:
Department of Nuclear Medicine, National Cheng Kung University Medical Center, Tainan, Taiwan, ROC
*
*Corresponding author. Tel.: +886 6 276 6188; fax: +886 6 275 9259. E-mail address:[email protected] (Y.K.Yang).
Get access

Abstract

The present study examined the relationship between the Lie scale scores and striatal D2/D3 receptor availability with respect to the cerebellum in 42 healthy community volunteers in Taiwan using single photon emission computed tomography (SPECT) with [123I]iodo-benzoaminde (IBZM). Even after controlling of age and educational level, subjects' Lie scale scores of the Maudsley personality inventory correlate negatively with D2/D3 receptor availability. Individual with higher Lie scale scores may have higher impulsivity due to lower dopaminergic availability.

Keywords

Striatal dopamine D2/D3 receptor availabilityPersonality inventorySocial desirability
Type
Short communication
Information
European Psychiatry , Volume 21 , Issue 1 , January 2006 , pp. 62 - 65
Copyright
Copyright © Elsevier SAS 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Adams, SAMatthews, CEEbbeling, CBMoore, CGCunningham, JEFulton, J, et al.The effect of social desirability and social approval on self-reports of physical activity. Am. J. Epidemiol. 2005;161:389–398.CrossRefGoogle ScholarPubMed
Breier, AKestler, LAdler, CElman, IWiesenfeld, NMalhotra, A, et al.Dopamine D2 receptor density and personal detachment in healthy subjects. Am. J. Psychiatry 1998;155:1440–1442.CrossRefGoogle ScholarPubMed
Cloninger, CRSvrakic, DMPrzybeck, TRA psychobiological model of temperament and character. Arch. Gen. Psychiatry 1993;50:975–990.CrossRefGoogle ScholarPubMed
Dicken, CKSimulated patterns on the Edwards personal preference schedule. J. Appl. Psychol. 1959;43:372–377.CrossRefGoogle Scholar
Eysenck, HJEysenck, SBGManual of the Eysenck personality questionnaire. London: University of London; 1975.Google Scholar
Eysenck, SBGEysenck, HJAn experimental investigation of “desirability” response set in a personality questionnaire. Life Sci. 1963;2:343–355.CrossRefGoogle Scholar
Farde, LGustavsson, JPJonsson, ED2 dopamine receptors and personality traits. Nature 1997;385:590.CrossRefGoogle ScholarPubMed
Hill, SYZezza, NWipprecht, GLocke, JNeiswanger, KPersonality traits and dopamine receptors (D2 and D4): linkage studies in families of alcoholics. Am. J. Med. Genet. 1999;88:634–641.3.0.CO;2-M>CrossRefGoogle Scholar
Krause, KHDresel, SHKrause, Jla Fougere, CAckenheil, MThe dopamine transporter and neuroimaging in attention deficit hyperactivity disorder. Neurosci. Biobehav. Rev. 2003;27:605–613.CrossRefGoogle ScholarPubMed
Kumari, VEysenck personality inventory: impulsivity/neuroticism and social desirability response set. Psychol. Rep. 1996;78:35–40.CrossRefGoogle ScholarPubMed
Laruelle, MImaging synaptic neurotransmission with in vivo binding competition techniques: a critical review. J. Cereb. Blood Flow Metab. 2000;20:423–451.CrossRefGoogle Scholar
Lee, IHChen, CCYang, YKYeh, TLChen, PSChiu, NTCorrelation between striatal dopamine D2 receptor density and neuroticism in community volunteers. Psychiatry Res. Neuroimaging 2005;138:259–264.CrossRefGoogle ScholarPubMed
Lu, FHYang, YCWu, JSWu, CHChang, CJA population-based study of the prevalence and associated factors of diabetes mellitus in southern Taiwan. Diabetes Med. 1998;15:564–572.3.0.CO;2-H>CrossRefGoogle ScholarPubMed
Macaskill, GTHopper, JLWhite, VHill, DJGenetic and environmental variation in Eysenck personality questionnaire scales measured on Australian adolescent twins. Behav. Genet. 1994;24:481–491.CrossRefGoogle ScholarPubMed
Molto, JSegarra, PAvila, CImpulsivity and total response speed to a personality questionnaire. Pers. Individ. Dif. 1993;15:97–98.CrossRefGoogle Scholar
Moresco, FMDieci, MVita, AMessa, CGobbo, CGalli, Let al.In vivo serotonin 5HT(2A) receptor binding and personality traits in healthy subjects: a positron emission tomography study. Neuroimage 2002;17:1470–1478.CrossRefGoogle ScholarPubMed
Pliszka, SRRogeness, GAMedrano, MADBH, MHPG, and MAO in children with depressive, anxiety, and conduct disorders: relationship to diagnosis and symptom ratings. Psychiatry Res. 1988;24:35–44.CrossRefGoogle Scholar
Plomin, ROwen, MJMcGuffin, PThe genetic basis of complex human behaviors. Science 1944;264:1733–1739.CrossRefGoogle Scholar
Rosa-Neto, PLou, HCCumming, PPryds, OKarrebaek, HLunding, J, et al.Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder. Neuroimage 2005;25:868–876.CrossRefGoogle ScholarPubMed
Schinka, JABusch, RMRobichaux-Keene, NA meta-analysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety. Mol. Psychiatry 2004;9:197–202.CrossRefGoogle ScholarPubMed
Sheehan, DVLecrubier, YSheehan, KHAmorim, PJanavs, JWeiller, E, et al.The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 1998;59:22–33 (quiz 4-57).Google ScholarPubMed
Wacker, JReuter, MHennig, JStemmler, GSexually dimorphic link between dopamine D2 receptor gene and neuroticism-anxiety. Neuroreport 2005;16:611–614.CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.