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Alcohol withdrawal seizures, epilepsy and brain trauma

Published online by Cambridge University Press:  27 August 2024

G. Dzhupanov ,
V. Nikolov  and
G. Slaveykov
G. Dzhupanov*
Affiliation:
1State psychiatric hospital for treatment of drug addiction and alcoholism
V. Nikolov
Affiliation:
1State psychiatric hospital for treatment of drug addiction and alcoholism
G. Slaveykov
Affiliation:
2University multiprofile hospital for active treatment in neurology and psychiatry St Naum, Sofia, Bulgaria
*
*Corresponding author.

Abstract

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Introduction

Alcohol addiction can lead to withdrawal seizures, but most patients do not develop epilesy. In some cases a permanent complication occurs - symptomatic epilepsy. In other cases epilepsy precedes alcohol addiction. Comorbidity may pose serious chalenges to treating clinicians. There are conflicting data regarding relationship between alcohol use, seizures and epilepsy (Scorza CA et al.,CLINICS 2020;75:e1770). Other factors like brain trauma may have impact in genesis of epileptic states as well.

Objectives

Evaluation of interplay between seizures, epilepsy and brain trauma in patients with alcohol use disorder.

Methods

Analysis of a case series in a hospital setting and review of relevant literature.

Results

In our series of cases the number of patients who have suffered epilepsy before the onset of alcohol use is small. In most of the hospitalized patients epilepsy occurred after the development of alcohol use disorder. In this group we observed that head and brain trauma play role in genesis of seizures and epilepsy and in some instances the reverse happens.

Conclusions

Our data indicate the potential role of brain trauma as predisposing and complicating factor in patients who developed seisures and epilepsy. Seizures sometimes increase the risk of brain trauma. Seizures and trauma are important factors in typology of Lesch (Lesch et al. 2011) and a serious evaluation in this direction is improtant, because its diagnostic, therapeutic and prognostic implications. Further clarification in this field is necessary.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 67 , Special Issue S1: Abstracts of the 32nd European Congress of Psychiatry , April 2024 , pp. S401
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of European Psychiatric Association
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