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Age of onset group characteristics in forensic patients with schizophrenia

Published online by Cambridge University Press:  15 April 2020

D. Vinokur ,
S.Z. Levine ,
D. Roe ,
A. Krivoy  and
T. Fischel
D. Vinokur
Affiliation:
Bar Ilan University
S.Z. Levine*
Affiliation:
Bar Ilan University Department of Community Mental Health, University of Haifa, Israel
D. Roe
Affiliation:
Department of Community Mental Health, University of Haifa, Israel
A. Krivoy
Affiliation:
Geha Mental Health Center, Petah-Tikva, Israel and Sackler, Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel
T. Fischel
Affiliation:
Geha Mental Health Center, Petah-Tikva, Israel and Sackler, Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel
*
*Corresponding author. Department of Community Mental Health, University of Haifa, Israel. Tel.: +972 489 6083; fax: +972 3 761 7374. E-mail address: [email protected] (S.Z. Levine).
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Abstract

This study aims to empirically identify age of onset groups and their clinical and background characteristics in forensic patients with schizophrenia. Hospital charts were reviewed of all 138 forensic patients with schizophrenia admitted to Geha Psychiatric Hospital that serves a catchment area of approximately 500,000 people, from 2000 to 2009 inclusive. Admixture analysis empirically identified early- (M = 19.99, SD = 3.31) and late-onset groups (M = 36.13, SD = 9.25). Early-onset was associated with more suicide attempts, violence before the age of 15, and early conduct problems, whereas late-onset was associated with a greater likelihood of violence after the age of 18 and marriage (P < 0.01). The current findings provide clinicians with a unique direction for risk assessment and indicate differences in violence between early- and late-onset schizophrenia, particularly co-occurrence of harmful behavioral phenotypes.

Keywords

AdmixtureSchizophreniaAge of onsetForensicEpidemiology
Type
Original article
Information
European Psychiatry , Volume 29 , Issue 3 , March 2014 , pp. 149 - 152
Copyright
Copyright © European Psychiatric Association 2014

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References

AbdelMalik, P, Husted, J, Chow, EW, Bassett, ASChildhood head injury and expression of schizophrenia in multiply affected families. Arch Gen Psychiatry 2003;60:231–236.CrossRefGoogle ScholarPubMed
Aleman, A, Kahn, RS, Selten, JPSex differences in the risk of schizophrenia: evidence from meta-analysis. Arch Gen Psychiatry 2003;60:565–571.CrossRefGoogle ScholarPubMed
Brill, N, Reichenberg, A, Rabinowitz, J, Harary, E, Lubin, G, Davidson, Met al.Accuracy of self-reported premorbid functioning in schizophrenia. Schizophr Res 2007;97:103–108.CrossRefGoogle Scholar
Byrne, M, Agerbo, E, Mortensen, PBFamily history of psychiatric disorders and age at first contact in schizophrenia: an epidemiological study. Br J Psychiatry Suppl 2002;43:s19–s25.CrossRefGoogle ScholarPubMed
DeLisi, LEThe significance of age of onset for schizophrenia. Schizophr Bull 1992;18:209–215.CrossRefGoogle Scholar
DeLisi, LE, Boccio, AM, Riordan, H, Hoff, AL, Dorfman, A, McClelland, Jet al.Familial thyroid disease and delayed language development in first admission patients with schizophrenia. Psychiatry Res 1991;38:39–50.CrossRefGoogle ScholarPubMed
Hafner, H, van der Heiden, W, Behrens, S, Gattaz, WF, Hambrecht, M, Loffler, Wet al.Causes and consequences of the gender difference in age at onset of schizophrenia. Schizophr Bull 1998;24:99–113.CrossRefGoogle ScholarPubMed
Hodgins, S, Tiihonen, J, Ross, DThe consequences of Conduct Disorder for males who develop schizophrenia: associations with criminality, aggressive behavior, substance use, and psychiatric services. Schizophr Res 2005;78:323–335.CrossRefGoogle ScholarPubMed
Howard, R, Castle, D, Wessely, S, Murray, RA comparative study of 470 cases of early-onset and late-onset schizophrenia. Br J Psychiatry 1993;163:352–357.CrossRefGoogle ScholarPubMed
Kay, SR, Fiszbein, A, Opler, LAThe positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987;13:261–276.CrossRefGoogle Scholar
Kohler, S, van der Werf, M, Hart, B, Morrison, G, McCreadie, R, Kirkpatrick, Bet al.Evidence that better outcome of psychosis in women is reversed with increasing age of onset: a population-based 5-year follow-up study. Schizophr Res 2009;113:226–232.CrossRefGoogle ScholarPubMed
Leung, A, Chue, PSex differences in schizophrenia, a review of the literature. Acta Psychiatr Scand Suppl 2000;401:3–38.CrossRefGoogle ScholarPubMed
Levine, SZ, Lurie, I, Kohn, R, Levav, ITrajectories of the course of schizophrenia: from progressive deterioration to amelioration over three decades. Schizophr Res 2011;126:184–191.CrossRefGoogle ScholarPubMed
Marshall, M, Lewis, S, Lockwood, A, Drake, R, Jones, P, Croudace, TAssociation between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic review. Arch Gen Psychiatry 2005;62:975–983.CrossRefGoogle ScholarPubMed
Marwaha, S, Johnson, S, Bebbington, P, Stafford, M, Angermeyer, MC, Brugha, Tet al.Rates and correlates of employment in people with schizophrenia in the UK, France and Germany. Br J Psychiatry 2007;191:30–37.CrossRefGoogle ScholarPubMed
Maurer, K, Hafner, HMethodological aspects of onset assessment in schizophrenia. Schizophr Res 1995;15:265–276.CrossRefGoogle Scholar
Mechanic, D, Blider, S, McAlpine, DDEmploying persons with serious mental illness. Health Aff (Millwood) 2002;21:242–253.CrossRefGoogle ScholarPubMed
Mullen, PSchizophrenia and violence: from correlations to preventive strategies. Adv Psychiatr Treat 2006;12:239.CrossRefGoogle Scholar
Norman, RM, Malla, AKDuration of untreated psychosis: a critical examination of the concept and its importance. Psychol Med 2001;31:381–400.CrossRefGoogle ScholarPubMed
Panariello, F, O’Driscoll, L, PdS, R, Tiwari, A, Manchia, M, Kennedy, Jet al.Age at onset in Canadian Schizophrenia patients: Admixture analysis. Schizophr Res 2009;122:278–279.CrossRefGoogle ScholarPubMed
Patterson, GR, DeBaryshe, BD, Ramsey, EA developmental perspective on antisocial behavior. Am Psychol 1989;44:329–335.CrossRefGoogle ScholarPubMed
Pulver, AE, Carpenter, WT, Adler, L, McGrath, JAccuracy of the diagnoses of affective disorders and schizophrenia in public hospitals. Am J Psychiatry 1988;145:218–220.Google ScholarPubMed
Rabinowitz, J, Fennig, SDifferences in age of first hospitalization for schizophrenia among immigrants and nonimmigrants in a national case registry. Schizophr Bull 2002;28:491–499.CrossRefGoogle Scholar
Rabinowitz, J, Haim, R, Reichenberg, A, Weiser, M, Kaplan, Z, Davidson, Met al.Association between functioning in adolescence prior to first admission for schizophrenia and affective disorders and patterns of hospitalizations thereafter. Schizophr Res 2005;73:185–191.CrossRefGoogle ScholarPubMed
Rabinowitz, J, Levine, SZ, Hafner, HA population based elaboration of the role of age of onset on the course of schizophrenia. Schizophr Res 2006;88:96–101.CrossRefGoogle ScholarPubMed
Reichenberg, A, Weiser, M, Rapp, MA, Rabinowitz, J, Caspi, A, Schmeidler, Jet al.Elaboration on premorbid intellectual performance in schizophrenia: premorbid intellectual decline and risk for schizophrenia. Arch Gen Psychiatry 2005;62:1297–1304.CrossRefGoogle ScholarPubMed
Rutter, M, Giller, H, Hagell, AAntisocial behavior by young people. Cambridge: Cambridge University Press; 1998.Google Scholar
Schurhoff, F, Golmard, JL, Szoke, A, Bellivier, F, Berthier, A, Meary, Aet al.Admixture analysis of age at onset in schizophrenia. Schizophr Res 2004;71:35–41.CrossRefGoogle Scholar
Suvisaari, JM, Haukka, J, Tanskanen, A, Lonnqvist, JKAge at onset and outcome in schizophrenia are related to the degree of familial loading. Br J Psychiatry 1998;173:494–500.CrossRefGoogle ScholarPubMed
Swanson, JW, Swartz, MS, Van Dorn, RA, Elbogen, EB, Wagner, HR, Rosenheck, RAet al.A national study of violent behavior in persons with schizophrenia. Arch Gen Psychiatry 2006;63:490–499.CrossRefGoogle ScholarPubMed
Valevski, A, Zalsman, G, Tsafrir, S, Lipschitz-Elhawi, R, Weizman, A, Shohat, TRate of readmission and mortality risks of schizophrenia patients who were discharged against medical advice. Eur Psychiatry 2011;27:496–499.CrossRefGoogle ScholarPubMed
Weiser, M, Kanyas, K, Malaspina, D, Harvey, PD, Glick, I, Goetz, Det al.Sensitivity of ICD-10 diagnosis of psychotic disorders in the Israeli National Hospitalization Registry compared with RDC diagnoses based on SADS-L. Compr Psychiatry 2005;46:38–42.CrossRefGoogle ScholarPubMed
Yonai, S., Levine, S.Z., Glicksohn, J.Trajectories of crime and familial characteristics: a longitudinal national population-based study. Crime & Delinquency [In Press].Google Scholar
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