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Acute phase proteins and personality disorders in schizophrenia

Published online by Cambridge University Press:  16 April 2020

M. Henry ,
A.L. Morera ,
A. Garcia-Hernandez ,
A. Orozco ,
E. Diaz ,
T. Rodriguez-Martos ,
M. Martin ,
L. Fernandez ,
C.R. Morales  and
M. Sangines
...Show all authors
M. Henry
Affiliation:
University Hospital of the Canary Islands, Ofra, La Laguna, Tenerife, Spain Department of Internal Medicine, Dermatology and Psychiatry, La Laguna Medical School, Ofra, La Laguna, Tenerife, Spain
A.L. Morera
Affiliation:
Department of Internal Medicine, Dermatology and Psychiatry, La Laguna Medical School, Ofra, La Laguna, Tenerife, Spain
A. Garcia-Hernandez
Affiliation:
Department of Internal Medicine, Dermatology and Psychiatry, La Laguna Medical School, Ofra, La Laguna, Tenerife, Spain
A. Orozco
Affiliation:
University Hospital of the Canary Islands, Ofra, La Laguna, Tenerife, Spain Department of Internal Medicine, Dermatology and Psychiatry, La Laguna Medical School, Ofra, La Laguna, Tenerife, Spain
E. Diaz
Affiliation:
Department of Internal Medicine, Dermatology and Psychiatry, La Laguna Medical School, Ofra, La Laguna, Tenerife, Spain University Hosiptal NS DeLa Candelaria, Santa Cruz, Tenerife, Spain
T. Rodriguez-Martos
Affiliation:
University Hospital of the Canary Islands, Ofra, La Laguna, Tenerife, Spain Department of Internal Medicine, Dermatology and Psychiatry, La Laguna Medical School, Ofra, La Laguna, Tenerife, Spain
M. Martin
Affiliation:
University Hospital of the Canary Islands, Ofra, La Laguna, Tenerife, Spain Department of Internal Medicine, Dermatology and Psychiatry, La Laguna Medical School, Ofra, La Laguna, Tenerife, Spain
L. Fernandez
Affiliation:
University Hospital of the Canary Islands, Ofra, La Laguna, Tenerife, Spain
C.R. Morales
Affiliation:
University Hospital of the Canary Islands, Ofra, La Laguna, Tenerife, Spain Department of Internal Medicine, Dermatology and Psychiatry, La Laguna Medical School, Ofra, La Laguna, Tenerife, Spain
M. Sangines
Affiliation:
University Hospital of the Canary Islands, Ofra, La Laguna, Tenerife, Spain
R. Gracia
Affiliation:
University Hospital of the Canary Islands, Ofra, La Laguna, Tenerife, Spain Department of Internal Medicine, Dermatology and Psychiatry, La Laguna Medical School, Ofra, La Laguna, Tenerife, Spain

Abstract

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Introduction:

Interest in the premorbid personality of schizophrenic patients is well established in the psychiatric literature. The relationship between personality disorders and acute phase proteins (APP) in schizophrenia is not well known.

Aim:

Investigating the relationship among acute phase proteins and personality disorders in schizophrenic patients in a sample of adult schizophrenic patients under psychiatric treatment in a general hospital health setting.

Material and Methods:

37 adult paranoid schizophrenics undergoing treatment in the University Hospital of the Canary Islands with DSM-IV diagnosis of paranoid schizophrenia are included. Years from onset 9.20 s.d. 6.29, age at onset 19.75 s.d. 4.73. The record of personality disorders as a secondary diagnosis in the medical chart was taking into account. A blood sample as routine standard analysis was carried out in each patient.

Results:

In 21 patients (56.7%) a personality disorder, mainly with paranoid and schizotypal traits, was registered. The percentage of each personality disorder is as follows, Schizotypal (16.2%), Paranoid (13.5%), Schizoid (2.7%), Paranoid and Schizotypal (24.3%). The results point to no significant correlation according to APP (C3, C4, alpha2-macroglobulin, alpha1-glicoprotein, ceruloplasmin) in the different diagnostic groups.

Discussion and conclusions:

In our study there is no evidence to support a significant correlation among APP and the different personality disorders in our sample of schizophrenics in spite of a positive correlation of APP and some psychopathology dimensions that has been communicated earlier elsewhere. In order to set some possible specificity of acute phase proteins and other clinical features in schizophrenia further research is required.

Type
Poster Session 1: Schizophrenia and Other Psychosis
Information
European Psychiatry , Volume 22 , Issue S1: 15th AEP Congress - Abstract book - 15th AEP Congress , March 2007 , pp. S114
Copyright
Copyright © European Psychiatric Association 2007
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