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The validity and reliability of the diagnosis of hyperkinetic disorders in the Danish Psychiatric Central Research Registry

Published online by Cambridge University Press:  23 March 2020

C. Mohr-Jensen*
Affiliation:
Research Unit of Child and Adolescent Psychiatry, Aalborg Psychiatric Hospital, Aalborg University Hospital, Aalborg, Denmark
S. Vinkel Koch
Affiliation:
Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region of Denmark and Institute of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
M. Briciet Lauritsen
Affiliation:
Research Unit of Child and Adolescent Psychiatry, Aalborg Psychiatric Hospital, Aalborg University Hospital, Aalborg, Denmark
H.-C. Steinhausen
Affiliation:
Research Unit of Child and Adolescent Psychiatry, Aalborg Psychiatric Hospital, Aalborg University Hospital, Aalborg, Denmark Clinical Psychology and Epidemiology, Department of Psychology, University of Basel, Basel, Switzerland Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland
*
* Corresponding author. E-mail address:[email protected] (C. Mohr-Jensen).
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Abstract

Objective

To validate the diagnosis of hyperkinetic disorders (HD) in the Danish Psychiatric Central Research Registry (DPCRR) for children and adolescents aged 4 to 15 given in the years 1995 to 2005.

Method

From a total of 4568 participants, a representative random subsample of n = 387 patients were used to validate the diagnosis. Patient files were systematically scored for the presence of ICD-10 criteria for HD and oppositional defiant disorder/conduct disorder (ODD/CD; F91). Further to this, an inter-rater reliability study was also conducted, whereby two experienced child and adolescent psychiatrists who were blind to patients discharge diagnoses, rated a random subsample of n = 101 participants.

Results

Information was available for 372 out of 387 patients. Out of n = 372 available files, n = 324 (86.8%) were evaluated to fulfil diagnostic criteria for HD. Due to missing information it was not possible to reach a conclusion for 5.1% of the cases, 3.8% of the diagnoses were registration errors, and in 4.3% of the files the diagnosis had to be rejected. Inter-rater agreement was high (κ = 0.83, z = 10.9, P < .001). The validity of hyperkinetic disorders, unspecified (F90.9) was lower and comorbid CD/ODD were under-diagnosed in the sample. All participants fulfilling HD criteria also fulfilled DSM-5-criteria for ADHD.

Conclusion

The risk of misclassification of patients with HD in the DPCRR is relatively low, with the exception of the diagnosis of hyperkinetic disorders, unspecified (F90.9).

Type
Original article
Copyright
Copyright © European Psychiatry 2016

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References

The World Health Organization The ICD-10 classification of mental and behavioural disorders – diagnostic criteria for research Geneva: WHO; 1993Google Scholar
American Psychiatric Association, Diagnostic and statistical manual of mental disorders 5th ed.American Psychiatric Association Washington DC 2013CrossRefGoogle Scholar
Lahey, BBPelham, WEChronis, AMassetti, GKipp, HEhrhardt, Aet al.Predictive validity of ICD-10 hyperkinetic disorder relative to DSM-IV attention-deficit/hyperactivity disorder among younger children J Child Psychol Psychiatry 2006; 47: 472479CrossRefGoogle ScholarPubMed
Santosh, PJTaylor, ESwanson, JWigal, TChuang, SDavies, Met al.Refining the diagnoses of inattention and overactivity syndromes: a reanalysis of the multimodal treatment study of attention-deficit hyperactivity disorder (ADHD) based on ICD-10 criteria for hyperkinetic disorder Clin Neurosci Res 2005; 5: 307314CrossRefGoogle Scholar
Bruchmuller, KMargraf, JSchneider, SIs ADHD diagnosed in accord with diagnostic criteria? Overdiagnosis and influence of client gender on diagnosis. J Consult Clin Psychol 2012; 80: 128138CrossRefGoogle ScholarPubMed
Munk-Jorgensen, POstergaard, SDRegister-based studies of mental disorders. Scand J Public Health 2011; 39: 170174CrossRefGoogle ScholarPubMed
Dalsgaard, SLeckman, JFNielsen, HSSimonsen, MGender and injuries predict stimulant medication use. J Child Adolesc Psychopharmacol 2014; 24: 253259CrossRefGoogle ScholarPubMed
Bro, SPKjaersgaard, MIParner, ETSorensen, MJOlsen, JBech, BHet al.Adverse pregnancy outcomes after exposure to methylphenidate or atomoxetine during pregnancy Clin Epidemiol 2015; 7: 139147CrossRefGoogle ScholarPubMed
Henriksen, LWu, CSSecher, NJObel, CJuhl, MMedical augmentation of labor and the risk of ADHD in offspring: a population-based study Pediatrics 2015; 135(3):e672–7CrossRefGoogle ScholarPubMed
Liew, ZRitz, BRebordosa, CLee, PCOlsen, JAcetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders. JAMA Pediatr 2014; 168: 313320CrossRefGoogle ScholarPubMed
Liew, ZRitz, Bvon Ehrenstein, OSBech, BHNohr, EAFei, Cet al. Attention-deficit/hyperactivity disorder and childhood autism in association with prenatal exposure to perfluoroalkyl substances: a nested case-control study in the Danish National Birth Cohort. Environ Health Perspect 2014CrossRefGoogle Scholar
Strom, MHansen, SOlsen, SFHaug, LSRantakokko, PKiviranta, Het al.Persistent organic pollutants measured in maternal serum and offspring neurodevelopmental outcomes – a prospective study with long-term follow-up Environ Int 2014; 68: 4148CrossRefGoogle ScholarPubMed
Zhu, JLOlsen, JLiew, ZLi, JNiclasen, JObel, CParental smoking during pregnancy and ADHD in children: the Danish national birth cohort. Pediatrics 134 2014 e382e388CrossRefGoogle ScholarPubMed
Strom, MHalldorsson, TIHansen, SGranstrom, CMaslova, EPetersen, SBet al.Vitamin D measured in maternal serum and offspring neurodevelopmental outcomes: a prospective study with long-term follow-up Ann Nutr Metab 2014; 64: 254261CrossRefGoogle ScholarPubMed
Atladottir, HOGyllenberg, DLangridge, ASandin, SHansen, SNLeonard, Het al.The increasing prevalence of reported diagnoses of childhood psychiatric disorders: a descriptive multinational comparison Eur Child Adolesc Psychiatry 2015; 24: 173183CrossRefGoogle ScholarPubMed
Jensen, CMSteinhausen, HCTime-trends in incidence rates of diagnosed attention-deficit/hyperactivity disorder across 16 years in a nationwide Danish Registry Study. J Clin Psychiatry 2015; 76: 334341CrossRefGoogle Scholar
Dalsgaard, SKvist, APLeckman, JFNielsen, HSSimonsen, MCardiovascular safety of stimulants in children with attention-deficit/hyperactivity disorder: a nationwide prospective cohort study. J Child Adolesc Psychopharmacol 2014; 24: 302310CrossRefGoogle ScholarPubMed
Dalsgaard, SLeckman, JFMortensen, PBNielsen, HSSimonsen, M Effect of drugs on the risk of injuries in children with attention-deficit hyperactivity disorder: a prospective cohort study. Lancet Psychiatry 2015 [Epub ahead of print]CrossRefGoogle Scholar
Dalsgaard, SOstergaard, SDLeckman, JFMortensen, PBPedersen, MGMortality in children, adolescents, and adults with attention-deficit hyperactivity disorder: a nationwide cohort study. Lancet 2015; 30: 21902196CrossRefGoogle Scholar
Steinhausen, HCBisgaard, CSubstance use disorders in association with attention-deficit/hyperactivity disorder, comorbid mental disorders, and medication in a nationwide sample. Eur Neuropsychopharmacol 2014; 24: 232241CrossRefGoogle Scholar
Steinhausen, HCHelenius, DThe association between medication for attention-deficit/hyperactivity disorder and cancer. J Child Adolesc Psychopharmacol 2013; 23: 208213CrossRefGoogle ScholarPubMed
Maibing, CFPedersen, CBBenros, MEMortensen, PBDalsgaard, SNordentoft, M Risk of schizophrenia increases after all child and adolescent psychiatric disorders: a nationwide study. Schizophr Bull 2014CrossRefGoogle Scholar
Dalsgaard, SHansen, NMortensen, PBDamm, DThomsen, PHReassessment of ADHD in a historical cohort of children treated with stimulants in the period 1969–1989. Eur Child Adolesc Psychiatry 2001; 10: 230239CrossRefGoogle Scholar
Linnet, KMWisborg, KSecher, NJThomsen, PHObel, CDalsgaard, Set al.Coffee consumption during pregnancy and the risk of hyperkinetic disorder and ADHD: a prospective cohort study Acta Paediatr 2009; 98: 173179CrossRefGoogle ScholarPubMed
Uggerby, POstergaard, SDRoge, RCorrell, CUNielsen, JThe validity of the schizophrenia diagnosis in the Danish Psychiatric Central Research Register is good. Dan Med J 60 2013 A4578Google Scholar
Lauritsen, MBJorgensen, MMadsen, KMLemcke, SToft, SGrove, Jet al.Validity of childhood autism in the Danish Psychiatric Central Register: findings from a cohort sample born 1990–1999 J Autism Dev Disord 2010; 40: 139148CrossRefGoogle ScholarPubMed
Phung, TKAndersen, BBHogh, PKessing, LVMortensen, PBWaldemar, GValidity of dementia diagnoses in the Danish hospital registers. Dement Geriatr Cogn Disord 2007; 24: 220228CrossRefGoogle ScholarPubMed
Lwanga, SKLemeshow, SSample size determination in health studies Geneva: World Health Organization; 1991Google Scholar
IBM Corp. IBM SPSS statistics for Windows, version 22.0 2013Google Scholar
Cantor, ABSample size calculations for Cohen’s Kappa. Psychol Methods 1996; 1: 150153CrossRefGoogle Scholar
Cohen, JTA coefficient of agreement for nominal scales. Psychol Meas 1960; 20: 3746CrossRefGoogle Scholar
Landis, JRKoch, GGThe measurement of observer agreement for categorical data. Biometrics 1977; 33: 159174CrossRefGoogle ScholarPubMed
The MTA Cooperative Group. A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. The MTA Cooperative Group. Multimodal Treatment Study of Children with ADHD. Arch Gen Psychiatry 1999; 56: 10731086CrossRefGoogle Scholar
Moderators and mediators of treatment response for children with attention-deficit/hyperactivity disorder: the Multimodal Treatment Study of children with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 1999; 56: 10881096CrossRefGoogle Scholar
Biederman, JFaraone, SVMilberger, SJetton, JGChen, LMick, Eet al.Is childhood oppositional defiant disorder a precursor to adolescent conduct disorder? Findings from a four-year follow-up study of children with ADHD. J Am Acad Child Adolesc Psychiatry 1996; 35: 11931204CrossRefGoogle ScholarPubMed
Biederman, JPetty, CRMonuteaux, MCMick, EParcell, TWesterberg, Det al.The longitudinal course of comorbid oppositional defiant disorder in girls with attention-deficit/hyperactivity disorder: findings from a controlled 5-year prospective longitudinal follow-up study. J Dev Behav Pediatr 2008; 29: 501507CrossRefGoogle ScholarPubMed
Mannuzza, SKlein, RGKonig, PHGiampino, TLHyperactive boys almost grown up. IV. Criminality and its relationship to psychiatric status. Arch Gen Psychiatry 1989; 46: 10731079CrossRefGoogle ScholarPubMed
Satterfield, JHFaller, KJCrinella, FMSchell, AMSwanson, JMHomer, LDA 30-year prospective follow-up study of hyperactive boys with conduct problems: adult criminality. J Am Acad Child Adolesc Psychiatry 2007; 46: 601610CrossRefGoogle ScholarPubMed
Satterfield, JSwanson, JSchell, ALee, FPrediction of antisocial behavior in attention-deficit hyperactivity disorder boys from aggression/defiance scores. J Am Acad Child Adolesc Psychiatry 1994; 33: 185190CrossRefGoogle ScholarPubMed
Mick, EFaraone, SVBiederman, JAge-dependent expression of attention-deficit/hyperactivity disorder symptoms. Psychiatr Clin North Am 2004; 27: 215224CrossRefGoogle ScholarPubMed
Murphy, P.The concordance between self-ratings of childhood and current symptoms of attention-deficit hyperactivity disorder. J Nerv Ment Dis 2003;191:341–3.CrossRefGoogle ScholarPubMed
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