Hostname: page-component-cd9895bd7-q99xh Total loading time: 0 Render date: 2024-12-23T13:12:05.706Z Has data issue: false hasContentIssue false

Norepinephrinergic antidepressants may increase self-injurious behavior in autistic syndromes

Published online by Cambridge University Press:  16 April 2020

R Krabe
Affiliation:
Division de Psychiatrie du Développement mental, Institutions universitaires de psychiatrie Genève (IUPG), 2, chemin du petit Bel-Air, CH-1225 Chêne-Bourg, Geneva, Switzerland
P Bovier
Affiliation:
Division de Psychiatrie du Développement mental, Institutions universitaires de psychiatrie Genève (IUPG), 2, chemin du petit Bel-Air, CH-1225 Chêne-Bourg, Geneva, Switzerland
Get access

Summary

There have been many contradictory reports on the effectiveness of antidepressant drug treatments in autistic syndromes with sell-injurious behavior (SIB). We report a retrospective case study in which norepinephrinergic antidepressants (inhibitors of the re-uptake of norepinephrine) increased SIB each time they were administered.

Type
Case report
Copyright
Copyright © European Psychiatric Association 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Aman, MGSingh, NNStewart, AWField, CJThe aberrant behavior checklist: a behavior rating scale for the assessment of treatment effects Am J Mem Defic 1985;89(5):485-91Google ScholarPubMed
Aman, MGWhite, AJVaithianathan, CTechan, CJPreliminary study of imipramine in profoundly retarded residents J Autism Dev Disord 1986;16(3):263-73CrossRefGoogle ScholarPubMed
Campbell, MFish, BShapiro, TFloyd, A JrImipramine in preschool autistic and schizophrenic children J Autism Child Schizophr 1971;1(3):267-82CrossRefGoogle ScholarPubMed
Carter, CHNortriptyline HCl as a tranquilizer for disturbed mentally retarded patients: a controlled study Am J Med Sci 1966;251: 465-7CrossRefGoogle ScholarPubMed
Gedye, ATrazodone reduced aggressive and self-injurious movements in a mentally handicapped male patient with autism J Clin Psychopharmacol 1991 ;11(4):275-6CrossRefGoogle Scholar
Ghaziuddin, MTsai, LDepression in autistic disorder Br J Psychiatry 1991;159: 721-3CrossRefGoogle ScholarPubMed
Huessy, HRRuoff, PATowards a rational drug usage in a state institution for retarded individuals Psychiatr J Univ Ott 1984;9(2): 56-8Google Scholar
Krug, DAArick, JRAlmond, PBehavior checklist for identifying severely handicapped individuals with high levels of autistic behavior J Child Psychol Psychiatry 1980;21: 221-9CrossRefGoogle ScholarPubMed
Pilkington, TLA report on “Tofranil” in mental deficiency Am J Mem Defic 1962;66(5):729-32Google Scholar
Schopler, EReichler, RIndividualized assessment and treatment for autistic and developmentally disabled children. Vol I: Psychoeducational Profile (PEP) Baltimore: University Park Press, 1979Google Scholar
Schopler, BReichler, RRentier, BThe Childhood Autism Rating Scale (CARS) New York: Irvington Publishers, 1986Google Scholar
Submit a response

Comments

No Comments have been published for this article.