Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-17T07:22:10.272Z Has data issue: false hasContentIssue false
  • English
  • Français

Measuring quality of life in schizophrenia

Published online by Cambridge University Press:  16 April 2020

SP McKenna
SP McKenna*
Affiliation:
Galen Research, Enterprise House, Manchester Science Park, Lloyd Street North, Manchester, M15 6SE, UK
Get access

Summary

A literature review identified nearly 500 papers in which references to quality of life (QoL) were made in the context of schizophrenia. Despite this, only two studies could be found where efforts had been made to assess the impact of pharmaceutical products on the QoL of patients with schizophrenia. It is argued that lack of progress in this area of research results from the absence of an adequate schizophrenia-specific QoL instrument. The present paper details the requirements for such an instrument, reviews health status instruments that have been used with schizophrenic patients and describes the methodology required for producing a new instrument. It is argued that the pharmaceutical industry should consider joint financing of such development work, given the importance of a reliable, valid and responsive outcome instrument for clinical trials. Such an instrument would also prove valuable when assessing alternative management programmes.

Keywords

quality of lifeschizophreniameasurementscales
Type
Research Article
Information
European Psychiatry , Volume 12 , Issue S3 , 1997 , pp. 267s - 274s
Copyright
Copyright © Elsevier, Paris 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Andreasen, NCNegative symptoms in schizophrenia. Arch Gen Psychiatry 1982; 39: 788–794CrossRefGoogle Scholar
Awad, AGQuality of life of schizophrenic patients on medications and implications for new drug trials. Hosp Community Psychiatry 1992; 43: 262–265Google ScholarPubMed
Becker, MDiamond, RSainfort, FA new patient focused index for measuring quality of life in persons with severe and persistent mental illnesses. Qual Life Res 1993; 2: 239–251CrossRefGoogle Scholar
Berzon, RHays, RDShumaker, SAInternational use, application and performance of health-related quality of life instruments. Qual Life Res 1993; 2: 367–368CrossRefGoogle ScholarPubMed
Blumenschein, KJohannesson, MIncorporating quality of life changes into economic evaluations of health care: an overview. Health Policy 1996; 36: 155–166CrossRefGoogle ScholarPubMed
Brazier, JEWalters, SJNicholl, JPKohler, BUsing the SF-36 and Euroqol on an elderly population. Qual Life Res 1996; 5: 195–204CrossRefGoogle Scholar
Bridges, KGage, AOliver, JEwert, Cet al.Changes in social support and quality of life: A case of a man with enduring psychotic illness Int J Soc Psychiatry 39 1993 142–151CrossRefGoogle ScholarPubMed
Cofer, CNAppleby, MHMotivation: Theory and Research. Heidelberg: Wiley, 1964Google Scholar
Cortina, JMWhat is coefficient alpha? An examination of theory and applications. J Appl Psychology 1993; 78: 98–104CrossRefGoogle Scholar
de Jong, Z, van der Heijde, D, McKenna, SP, Whalley, D. The reliability and construct validity of the RAQoL: A rheumatoid arthritis-specific quality of life instrument. Br J Rheumatol (In press)Google Scholar
Dixon, PHeaton, JLong, AWarburton, AReviewing and applying the SF-36Outcomes Briefing August 1994 3–25Google Scholar
Englert, ISAhrens, BGebhardt, MKliefoth, Met al.Implications of the concepts “coping” and “quality of life” for criteria of course and outcome Pharmacopsychiatry 27 1994 34–36CrossRefGoogle ScholarPubMed
Festinger, LATheory of Cognitive Dissonance. New York: Stanford University Press, 1957Google Scholar
Guyatt, GHFeeny, DHPatrick, DLMeasuring quality of life. Ann Intern Med 1993; 118: 622–629CrossRefGoogle Scholar
Hayes, VMorris, JWolfe, CMorgan, MThe SF-36 health survey questionnaire: is it suitable for use with older adults. Age Ageing 1995; 24: 120–125CrossRefGoogle ScholarPubMed
Herzberg, FWork and the Nature of Man. Stanford: World, 1966Google Scholar
Holmes, SJMcKenna, SPDoward, LCShalet, SMDevelopment of a questionnaire to assess the quality of life of adults with growth hormone deficiency. Endocrinol Metab 1995; 2: 63–69Google Scholar
Hull, CLPrinciples of Behavior. Cleveland: Appleton-Century-Crofts, 1943Google Scholar
Hunt, SMMcKenna, SPThe QLDS: A scale for the measurement of quality of life in depression. Health Policy 1992; 22: 307–319CrossRefGoogle ScholarPubMed
Hunt, SMMcKenna, SPMeasuring quality of life in psychiatry. In: Walker, ARosser, RM eds. Quality of Life Assessment: Key Issues in the 1990s. New York: Kluwer Academic Publishers, 1993; 345–354Google Scholar
Jachuck, SJBrierley, HJachuk, SWillcox, PThe effect of hypertensive drugs on the quality of life. Journal of the Royal College of General Practitioners 1982; 32: 103–105Google Scholar
Jahoda, MEmployment and Unemployment. A Social Psychological Analysis. Amsterdam: The Cambridge University Press, 1982Google Scholar
Kay, SROpler, LALindenmayer, JPReliability and validity of the positive and negative syndrome scale for schizophrenics. Psychiatry Res 1988; 23: 99–110CrossRefGoogle ScholarPubMed
Kreiner, SValidation of index scales for analysis of survey data. In: Dean, K eds. Population Health Research - Linking Theory and Methods. Cambridge: Sage, 1993; 116–144Google Scholar
Lauer, GStegmuller-Koenemund, UBereichsspezifische subjektive Lebensqualitat und krankheitsbedingte Einschrankungen chronisch schizophrener Patienten. Psychiatr Prax 1994; 21: 70–73Google Scholar
Lehman, AFThe well-being of chronic mental patients. Arch Gen Psychiatry 1983; 40: 369–373CrossRefGoogle ScholarPubMed
Lehman, AFPossidente, SHawker, FThe quality of life of chronic patients in a state hospital and in community life. Hosp Community Psychiatry 1986; 37: 901–907Google Scholar
Levine, SCroog, SHThe primary care physician and the patient's quality of life Quality of Life in Cardiovascular Care 1984 5–19Google Scholar
Maslow, AHMotivation and Personality 2nd edBeverly Hills: Harper & Row, 1970Google Scholar
McClelland, DCAtkinson, JWClark, RWLowell, ELThe Achievement Motive. New York: Appleton-Century-Crofts, 1953CrossRefGoogle Scholar
McDowell, INewell, CMeasuring Health: a Guide to Rating Scales and Questionnaires. New York: Oxford University Press, 1987Google Scholar
McKenna, SPQuality of life assessment in the conduct of economic evaluations of medicines. Brit J Medical Economics 1995; 8: 33–38Google Scholar
McKenna, SPIncorporating quality of life changes into economic evaluations of health care: an overview. Health Policy 1996; 37: 199–204CrossRefGoogle Scholar
McKenna, SPDoward, LCMeasuring quality of life in recurrent genital herpes. Eur Rev App Psychology 1995; 45: 289–295Google Scholar
McKenna, SPPatrick, DThe development of a migraine-specific quality of life measure for multi-national clinical trials. Cephalalgia 15Suppl 141995 280Google Scholar
Meltzer, HYBurnett, SBastani, BRamirez, LFEffects of six months of clozapine treatment on the quality of life of chronic schizophrenic patients. Hosp Community Psychiatry 1990; 41: 892–897Google ScholarPubMed
National Health Service Review Working Paper No 6 Medical Audit. Oxford: HMSO, 1989Google Scholar
Oliver, JThe Social care directive: Development of a quality of life profile for use in community services for the mentally ill. Soc Work Soc Sci Review 1991; 3: 5–45Google Scholar
Overall, JEHollister, LEAssessment of depression using the Brief Psychiatric Rating Scale. In: Sartorius, NBan, TA eds. Assessment of Depression. London: Springer, 1986; 159–178CrossRefGoogle Scholar
Patrick, DLBergner, MMeasurement of Health Status in the 1990's. Annu Rev Public Health 1990; 11: 165–183CrossRefGoogle Scholar
Rasch, GProbabilistic Models for some Intelligence and Attainment Tests. Berlin: University of Chicago Press, 1980Google Scholar
Skantze, KMalm, UDencker, SJMay, PRACorrigan, PComparison of quality of life with standard of living in schizophrenic out-patients. Br J Psychiatry 1992; 161: 797–801CrossRefGoogle ScholarPubMed
Spilker, BIntroduction. In: Spilker, B eds. Quality of Life Assessments in Clinical Trials Second editionChicago: Raven Press, 1996; 1–10Google Scholar
Strauss, JCCarpenter, WTThe prediction of outcome in schizophrenia, I: characteristics of outcome. Arch Gen Psychiatry 1972; 27: 739–746CrossRefGoogle Scholar
Streiner, DNorman, GHealth Measurement Scales. New York: Oxford University Press, 1989Google Scholar
Tennant, AMcKenna, SPConceptualizing and defining outcome. Br J Rheumatol 1995; 34: 899–900CrossRefGoogle ScholarPubMed
Tennant, AHillman, MChamberlain, MAFear, JMissing values and the MOS SF36: An over-55 year old sample with arthritis Annual Scientific Meeting of American College of Rheumatology October 1995 Arthritis Rheum 38 1995; S178Google Scholar
van Dam, FQuality of life: Methodological aspects. Cancer Bulletin (Paris) 1986; 73: 607–613Google ScholarPubMed
Weissman, MMBothwell, SThe assessment of social adjustment by patient self-report Arch Gen Psychiatry 33 1976 1111–1115CrossRefGoogle ScholarPubMed
Weissman, MMPaykel, ESPrusoff, BASocial Adjustment Scale Handbook Oxford: State Psychiatric Institute, 1990Google Scholar
Wiersma, DDe Jong, AOrmel, JThe Groningen Social Disabilities Schedule: Development, relationship with ICIDH, and psychometric properties Int J Rehabil Res 11 1988 213–224CrossRefGoogle ScholarPubMed
World Health Organization International Classification of Impairments, Disabilities and Handicaps: A Manual of classification relating to consequences of disease New York: WHO, 1980Google Scholar
Submit a response

Comments

No Comments have been published for this article.