Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-25T20:09:06.589Z Has data issue: false hasContentIssue false

A French family study of two groups of alcoholic men

Published online by Cambridge University Press:  16 April 2020

F Amiel-Lebigre*
Affiliation:
Génétique, Neuro-Génétique et Comporlement, URA 1294 CNRS
M Duyme
Affiliation:
Génétique, Neuro-Génétique et Comporlement, URA 1294 CNRS
S Tordjman
Affiliation:
UER Biomédicale, Université Paris V, 45, rue des Saints-Pères, 75270Paris Cedex 06, France
*
*Correspondence and reprints: 17, rue des Plantes, 75014 Paris, France
Get access

Summary

Alcoholic and psychiatric family history were investigated in two groups of alcoholics, recruited differently, and controls. Alcoholics with or without a family history of alcoholism (AFH + and AFH − ) were compared with regard to professional qualifications, personal psychiatric history, age at onset and reasons given for becoming alcoholic. The results can be summarized as follows: the family ‘aggregate’ of alcoholism found was independent of the recruitment. This was not the case for personal psychiatric history for which a gradient was found in the two alcoholic groups. Rates of alcoholism were higher in both the first and second degree relatives. Alcoholics with AFH+ and AFH− differed significantly with regard to inducement by profession, and tended to differ as to age of onset.

Type
Original article
Copyright
Copyright © Elsevier, Paris 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Amark, C (1951) A study in alcoholism Acta Psychiatr Neurol Scand suppl 70, 1283Google ScholarPubMed
Amiel-Lebigre, F (1988) Echelles de dépistage et de diagnostic de l’Alcoolisme Rev Alcool 33, 12433Google Scholar
Atkinson, RMTurner, JAKofoed, LLTolson, RL (1985) Early versus late onset alcoholism in older persons: preliminary findings Alcohol Clin Exp Res 6, 513515CrossRefGoogle Scholar
Bohman, M (1978) Some genetic aspects of alcoholism and criminality Arch Gen Psychiatry 35, 269276CrossRefGoogle ScholarPubMed
Bohman, MSivgardsson, SCloninger, CR (1981) Maternal inheritance of alcohol abuse: Cross-fostering analysis of adopted women Arch Gen Psychiatry 38, 965969CrossRefGoogle ScholarPubMed
Cadoret, RJGath, A (1978) Inheritance of alcoholism in adoptees Br J Psychiatry 132, 252258CrossRefGoogle Scholar
Cadoret, RJO’Gorman, TWTroughton, EHeywood, E (1985) Alcoholism and antisocial personality: interrelationships, genetic and environmental factors Arch Gen Psychiatry 42, 161167CrossRefGoogle ScholarPubMed
Cloninger, CRBohman, MSigvardsson, S (1981) Inheritance of alcohol abuse: Cross-fostering analysis of adopted men Arch Gen Psychiatry 38, 861868CrossRefGoogle ScholarPubMed
Cloninger, CR (1987) Neurogenic adaptative mechanisms in alcoholism Science 236, 410416CrossRefGoogle Scholar
Cloninger, CRReich, TSigvardsson, Svon Knorring, ALBohman, M (1988) Effects of changes in alcohol use between generations on inheritance of alcohol abuse.In: Alcoholism: Origins and Outcome (Mose, RMBarret, JE, eds) Raven Press Ltd, New York, 4974Google Scholar
Cook, BLWinokur, G (1985) A family study of familial positive vs familial negative alcoholics J Nerv Ment Dis 3, 175178CrossRefGoogle Scholar
Cotton, NS (1979) The familial incidence of alcoholism. A review J Stud Alcohol 40, 89116CrossRefGoogle ScholarPubMed
Diagnostic and Statistical Manual of Mental Disorders (1987) 3rd edn revised (DSM III-R). American Psychiatric Association, Washington DCGoogle Scholar
Feighner, JPRobins, EGuze, SBWoodruff, ARWinokur, GMunoz, R (1972) Diagnostic criteria for use in psychiatric research Arch Gen Psychiatry 26, 5763CrossRefGoogle ScholarPubMed
Frances, RJTimm, SBucky, S (1980) Studies of familial and non familial alcoholism Arch Gen Psychiatry 37, 564566CrossRefGoogle Scholar
Gabrielli, WFPlomin, R (1985) Drinking behavior in the Colorado adoptee and twin sample J Stud Alcohol 46, 2431CrossRefGoogle ScholarPubMed
Gilligan, SBReich, TCloninger, CR (1987) Etiologic heterogeneity in alcoholism Genet Epidemiol 4, 395414CrossRefGoogle ScholarPubMed
Goodwin, DW (1979) Alcoholism and heredity Arch Gen Psychiatry 36, 5761CrossRefGoogle ScholarPubMed
Goodwin, DW (1981) Family studies of alcoholism J Stud Alcohol 42, 156162CrossRefGoogle ScholarPubMed
Goodwin, DW (1983) Familial alcoholism Subst Alcohol Actions-Misuse 4, 129136Google ScholarPubMed
Goodwin, DW (1985) Alcoholism and genetics. The sons of the fathers Arch Gen Psychiatry 42, 171174CrossRefGoogle ScholarPubMed
Goodwin, DWSchulsinger, FHermansen, LGuze, SBWinokur, G (1973) Alcohol problems in adopted raised apart from alcoholic biological parents Arch Gen Psychiatry 28, 238243CrossRefGoogle Scholar
Goodwin, DWSchulsinger, FMoller, NHermansen, LWinokur, GGuze, SG (1974) Drinking problems in adopted and non adopted sons of alcoholics Arch Gen Psychiatry 31, 164169CrossRefGoogle Scholar
Gurling, HMDOppenheim, BEMurray, RM (1984) Depression, criminality and psychopathology associated with alcoholism: evidence from a twin study Acta Genet Med Gemellol 33, 333339CrossRefGoogle ScholarPubMed
Helzer, JEPryzbeck, TR (1988) The co-occurence of alcoholism with other psychiatric disorders in the general population and its impact on treatment J Stud Alcohol 49, 219224CrossRefGoogle Scholar
Helzer, JECanina, GJEng-Kung, YBland, RCChung Kyoon, LHai-Gwo, HNewman, S (1990) Alcoholism- North America and Asia. A comparison of population surveys with the diagnostic interview schedule Arch Gen Psychiatry 47, 313319CrossRefGoogle Scholar
Hesselbrock, VMHesselbrock, MNStabenau, JR (1985) Alcoholism in men patients subtyped by family history and antisocial personality J Stud Alcohol 46, 5964CrossRefGoogle ScholarPubMed
Hrubec, ZOmenn, GS (1981) Evidence of genetic predisposition to alcoholic cirrhosis and psychosis: twin concordances for alcoholism and its biological and points by zygosity among male veterans Alcohol Clinic Exp Res 2, 207215CrossRefGoogle Scholar
Index Alphabetique pour le Dichiffremenl des Categories Socio-professionnelles (1983) 1st ed, INSEEGoogle Scholar
Irwin, MSchuckit, MSmith, TL (1990) Clinical importance of age at onset in type 1 and type 2 primary alcoholics Arch Gen Psychiatry 47, 320324CrossRefGoogle ScholarPubMed
Jellineck, EMJolliffe, N (1940) Effect of alcohol on the individual. Review of thelitterature of 1939 Q J Stud Alcohol 1, 110181CrossRefGoogle Scholar
Jones, RW (1972) Alcoholism among relatives of alcoholic patients Q J Stud Alcohol 33, 810813Google ScholarPubMed
Kaij, L (1960) Alcoholism in twins: Studies on the etiology and Sequels of Abuse of Alcohol Almqvist and Wiksells, StockholmGoogle Scholar
Leohlin, JC (1972) An analysis of alcohol-related questionnaire items from the National Merit twin study Ann NY Acad Set 197, 117120CrossRefGoogle Scholar
Mc Cords, WMc Cord, JGudeman, J (1960) Origins of Alcoholism Stanford University Press, StanfordGoogle Scholar
Mc Kenna, TPickens, R (1981) Alcoholic children of alcoholics J Stud Alcohol 42, 10211029CrossRefGoogle Scholar
Menninger, KA (1938) Man Against Himself Harcourt Brace, New YorkGoogle Scholar
Merikangas, KR (1990) The genetic epidemiology of alcoholism Psychol Med 20, 1122CrossRefGoogle ScholarPubMed
Merikangas, KRLeckman, JFPrusoff, BAPauls, DLWeissman, MM (1985) Familial transmission of depression and alcoholism Arch Gen Psychiatrv 42, 367372CrossRefGoogle ScholarPubMed
Nicholls, RCBilbro, WC (1966) The diagnosis of twin zygosity Acta Genet 16, 265275Google Scholar
Partanen, JBruun, KMarkkanen, T (1966) Inheritance of Drinking Behavior: A Study of Intelligence, Personality and Use of Alcohol of Adult Twins The Finnish Foundation for Alcohol Studies, HelsinkiGoogle Scholar
Pelc, I (1977) Contribution à l’étude de la psychopathologie de l’alcoolisme chronique Brussels, ULBGoogle Scholar
Penick, ECRead, ECCrowley, PAPowell, BJ (1978) Differentiation of alcoholics by family history ./ Stud Alcohol 39, 19441948CrossRefGoogle ScholarPubMed
Penick, ECPowell, BJBingham, SFLiskow, BIMiller, NSRead, MR (1987) A comparative study of familial alcoholism J Stud Alcohol 48, 2, 136146CrossRefGoogle ScholarPubMed
Reich, TRice, JCloninger, CRLewis, C (1980) The contribution of affected parents to the pool of affected individuals: Path analysis of the segregation distribution for alcoholism.In: The Social Consequences of Psychiatric Illness (Robbins, LNClayton, PJWing, JK, eds) Brunner/Mazel,New YorkGoogle Scholar
Roubertoux, PCarlier, M (1976) Genetique el coinportement Masson, ParisGoogle Scholar
Roubertoux, PCapron, C (1990) Are intelligence differences hereditarily transmitted? Cah Psychol Cog/Eur Bull Cog Psychol 10, 555594Google Scholar
Schuckit, MA (1982) The history of psychotic symptoms in alcoholics J Clin Psychiatry 43, 5357Google ScholarPubMed
Schuckit, MA (1983) Alcoholic men with no alcoholic first degree relatives Am J Psychiatry 4, 439443Google Scholar
Schuckit, MAGoodwin, DAWinokur, G (1972) A study of alcoholism in half siblings Am J Psychiatry 129, 11321136CrossRefGoogle Scholar
Thomson, WDOrvaschel, HPrusoff, BAKidd, KK (1982) An evaluation of the family history method for ascertaining psychiatric disorders Arch Gen Psychiatry 39, 5358CrossRefGoogle Scholar
Volicer, BJVolicier, LD’Angelo, N (1983) Variation in length of time to development of alcoholism by family history of problem drinking Drug Alcohol Depend 12, 6983CrossRefGoogle ScholarPubMed
Winokur, GReich, TRimmer, JPitts, FN (1970) Alcoholism III. Diagnosis and familial psychiatric illness in 259 alcoholics probands Arch Gen Psychiatry 23, 104111CrossRefGoogle Scholar
Submit a response

Comments

No Comments have been published for this article.