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Cortisol Response To Interpersonal Stress in Young Adults With Borderline Personality Disorder: A Pilot Study

Published online by Cambridge University Press:  06 March 2008

Marc Walter ,
Jean-François Bureau ,
Bjarne M. Holmes ,
Eszter A. Bertha ,
Michael Hollander ,
Joan Wheelis ,
Nancy Hall Brooks  and
Karlen Lyons-Ruth
Marc Walter*
Affiliation:
Department of Psychiatry, University of Basel, Wilhelm Klein-Strasse 27, CH-4025Basel, Switzerland Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA
Jean-François Bureau
Affiliation:
Department of Psychiatry, Cambridge Hospital, Harvard Medical School, Cambridge, MA, USA
Bjarne M. Holmes
Affiliation:
Department of Psychiatry, Cambridge Hospital, Harvard Medical School, Cambridge, MA, USA School of Life Sciences, Heriot-Watt University, UK
Eszter A. Bertha
Affiliation:
Department of Psychiatry, Cambridge Hospital, Harvard Medical School, Cambridge, MA, USA
Michael Hollander
Affiliation:
Two Brattle Center, Cambridge, MA, USA
Joan Wheelis
Affiliation:
Two Brattle Center, Cambridge, MA, USA
Nancy Hall Brooks
Affiliation:
Department of Psychiatry, Cambridge Hospital, Harvard Medical School, Cambridge, MA, USA
Karlen Lyons-Ruth
Affiliation:
Department of Psychiatry, Cambridge Hospital, Harvard Medical School, Cambridge, MA, USA
*
∗Corresponding author. Department of Psychiatry, University of Basel, Wilhelm Klein-Strasse 27, CH-4025 Basel, Switzerland. E-mail address: [email protected] (M. Walter).
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Abstract

Hypothalamic–pituitary–adrenal axis dysregulation after stress was found to be associated with borderline personality disorder (BPD). Nine female BPD young adults and 12 control subjects were investigated for stress reactivity and recovery after an interpersonal conflict discussion with their mothers. BPD subjects showed a delayed cortisol response after psychosocial stress.

Keywords

Borderline personality disorderPsychosocial stressCortisol response
Type
Short communication
Information
European Psychiatry , Volume 23 , Issue 3 , April 2008 , pp. 201 - 204
Copyright
Copyright © European Psychiatric Association 2008

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