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Association between flupenthixol treatment and emergence of manic symptoms

Published online by Cambridge University Press:  16 April 2020

D. Becker ,
Y. Grinberg ,
A. Weizman  and
R. Mester
D. Becker*
Affiliation:
Ness-Ziona Mental Health Center, Ness-Ziona, P.O. Box 1, Ness-Ziona74450, Israel
Y. Grinberg
Affiliation:
Ness-Ziona Mental Health Center, Ness-Ziona, P.O. Box 1, Ness-Ziona74450, Israel
A. Weizman
Affiliation:
Geha Psychiatric Hospital, Rabin Medical Center, Petah Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
R. Mester
Affiliation:
Ness-Ziona Mental Health Center, Ness-Ziona, P.O. Box 1, Ness-Ziona74450, Israel
*
*Corresponding author.
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Summary

Background.

Flupenthixol is an antipsychotic drug with known mood-elevating properties. Its propensity to induce manic symptoms has not been investigated.

Methods and results.

We describe six patients, four with schizophrenia and two with bipolar disorder, in whom flupenthixol treatment was associated with emergence of manic symptoms.

Conclusions.

Patients treated with flupenthixol should be carefully monitored for the emergence of manic symptoms.

Keywords

FlupenthixolManiaAntipsychotic
Type
Original article
Information
European Psychiatry , Volume 17 , Issue 6 , October 2002 , pp. 349 - 352
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2002

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References

Dwight, MMKeck, PEStanton, SPStrakowski, SMMcElroy, SI. Antidepressant activity and mania associated with risperidone treatment of schizoaffective disorder. Lancet 1994;344:554–5.CrossRefGoogle ScholarPubMed
Hamilton, MCard, IRWallis, GGMahmoud, MR. A comparative trial of the decanoates of flupenthixol and fluphenazine. Psychopharmacology 1979;64:225–9.Google ScholarPubMed
Hsien-Yuan, LYui-Ching, LWen-Ho, C. Mania induced by risperidone: dose related?. J Clin Psychiatry 1998;59:85.Google Scholar
Kelly, HRFreeman, HCBannig, BSchiff, AA. Clinical and social comparison of fluphenazine decanoate and flupenthixol decanoate in the community maintenance therapy of schizophrenia. Int Pharmacopsychiatry 1977;12:54–64.CrossRefGoogle ScholarPubMed
Szabo, CP. Depot flupenthixol-induced mania. S Afr Med J 1993;83:442.Google ScholarPubMed
Trueman, ARValentine, MG. Flupenthixol decanoate in schizophrenia. Br J Psychiatry 1974;124:58–9.CrossRefGoogle Scholar
Wistedt, BRanata, J. A comparative double-blind study of flupenthixol decanoate and fluphenazine decanoate in the treatment of patient relapsing in schizophrenia symptomatology. Acta Psychiatr Scand 1983;67:378–88.CrossRefGoogle Scholar
Young, JPRHughes, WCLader, MH. A controlled comparison of flupenthixol and amitriptyline in depressed outpatients. Br Med J 1976;1:1116–8.CrossRefGoogle ScholarPubMed
Zolezzi, MGhany Badr, MGA. Risperidone-induced mania. Ann Pharmacother 1999;33:380.CrossRefGoogle ScholarPubMed
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