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826 – An Incidence Study of Diagnosed Autism-spectrum Disorders among Immigrants to the Netherlands

Published online by Cambridge University Press:  15 April 2020

E. van der Ven ,
F. Termorshuizen ,
W. Laan ,
E. Breetvelt ,
J. van Os  and
J.-P. Selten
E. van der Ven
Affiliation:
Riverduinen Foundation, Leiden Psychiatry and Neuropsychology, Maastricht University, Maastricht
F. Termorshuizen
Affiliation:
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht
W. Laan
Affiliation:
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht
E. Breetvelt
Affiliation:
Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
J. van Os
Affiliation:
Psychiatry and Neuropsychology, Maastricht University, Maastricht Department of Psychosis Studies, King's College London Institute, London, UK
J.-P. Selten
Affiliation:
Riverduinen Foundation, Leiden Psychiatry and Neuropsychology, Maastricht University, Maastricht

Abstract

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Objective:

To estimate the risk of developing autism-spectrum disorder (ASD) in children born to immigrants as compared to children of Dutch-born parents.

Method:

Retrospective, population-based cohort study of all live births (N= 106,953) between 1998 and 2007 in a circumscribed geographical region in the Netherlands. Cohort members were linked to the Psychiatric Case Register to identify diagnosed cases.

Results:

518 cases of ASD were identified, including 150 children with autism and 368 children with Asperger syndrome or PDD-NOS. Children born to migrants from developing countries were at significantly lower risk of ASD (rate ratio (RR)= 0.6, 95% (CI) 0.5-0.9) than children of Dutch-born parents. Within the ASD group, the risk for the subgroup with Asperger syndrome and PDD-NOS was reduced (RR= 0.4, 95% CI 0.3-0.6), whereas that for narrowly defined autism was nonsignificantly increased (RR= 1.4, 95% CI 0.9-2.4). Migrant groups did not differ in age at diagnosis.

Conclusion:

The results echo Swedish findings indicating a reversal of risk gradient in children of parents from developing countries, specifically a decreased risk for high-functioning and increased risk for low-functioning autism.

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E289
Copyright
Copyright © European Psychiatric Association 2013
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