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2846 – A Multicentre Study on Adult Attention-Deficit/Hyperactivity Disorder in Subjects with Affective Disorders: Role of Personality Traits and Clinical Implications

Published online by Cambridge University Press:  15 April 2020

M. Di Nicola ,
L. Sala ,
L. Romo ,
V. Catalano ,
D. Tedeschi ,
C. Even ,
C. Dubertret ,
M. Mazza ,
G. Martinotti  and
A. Callea
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M. Di Nicola
Affiliation:
Department of Psychiatry, Catholic University Medical School, Rome, Italy
L. Sala
Affiliation:
CMME, Sainte-Anne Hospital, Paris Descartes University
L. Romo
Affiliation:
CMME, Sainte-Anne Hospital, Paris Descartes University University Paris Ouest Nanterre La Défense, Laboratoire Evaclipsy, Paris
V. Catalano
Affiliation:
Department of Psychiatry, Catholic University Medical School, Rome, Italy
D. Tedeschi
Affiliation:
Department of Psychiatry, Catholic University Medical School, Rome, Italy
C. Even
Affiliation:
CMME, Sainte-Anne Hospital, Paris Descartes University
C. Dubertret
Affiliation:
Louis Mourier University Hospital, Colombe, France
M. Mazza
Affiliation:
Department of Psychiatry, Catholic University Medical School, Rome, Italy
G. Martinotti
Affiliation:
Department of Neuroscience and Imaging, Chair of Psychiatry, G. D’Annunzio University, Chieti
A. Callea
Affiliation:
Science of Education, LUMSA University, Rome, Italy
J.D. Guelfi
Affiliation:
CMME, Sainte-Anne Hospital, Paris Descartes University
F. Rouillon
Affiliation:
CMME, Sainte-Anne Hospital, Paris Descartes University Centre of Psychiatry and Neurosciences, INSERM U 894, Paris, France
L. Janiri
Affiliation:
Department of Psychiatry, Catholic University Medical School, Rome, Italy
P. Gorwood
Affiliation:
CMME, Sainte-Anne Hospital, Paris Descartes University Centre of Psychiatry and Neurosciences, INSERM U 894, Paris, France

Abstract

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Background:

A significant comorbidity between attention-deficit/hyperactivity disorder (ADHD) and affective disorders has been consistently reported in adults. Less data regarding the role of personality traits, and the influence of ADHD co-occurrence on clinical characteristics and outcome of mood disorders are currently available.

Methods:

The sample consisted of 296 subjects, divided into three homogeneous groups according to demographic characteristics: 106 subjects diagnosed with major depressive disorder, 92 with bipolar disorders and 98 healthy controls. ADHD diagnosis was based on DSM-IV-TR criteria. Childhood and adult ADHD features were measured with the Wender Utah Rating Scale (WURS), the Adult ADHD Self-rating Scale (ASRS) and the Brown Attention Deficit Disorder Scale (ADD). The Hospital Anxiety and Depression Scale (HAD) and the Revised NEO Personality Inventory (NEO-PI-R) were also administered to the clinical groups, in order to investigate depressive/anxious symptoms and personality dimensions.

Results:

The prevalence of adult ADHD in subjects with bipolar disorders or major depressive disorder was 22.0% and 8.5% respectively (p < .001), compared to 3.1% in healthy controls. Significant associations between personality traits, depressive/anxious symptoms and ADHD features were found.

Discussion:

The present study emphasises the close relationship between affective disorders, especially bipolar disorders, and ADHD in adults. Our findings support the need to assess subjects with mood disorders in the clinical setting for possible co-existing ADHD and to further investigate personality traits to better understand the etiology of affective disorders and ADHD co-occurrence.

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E1715
Copyright
Copyright © European Psychiatric Association 2013
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