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11C-PIB PET in subjective cognitive impairment

Published online by Cambridge University Press:  16 April 2020

J. Rodda*
Affiliation:
Department of Mental Health Sciences, University College London, Windeyer Building, 46, Cleveland Street, LondonW1T 4JF, UK
A. Okello
Affiliation:
MRC Clinical Science Centre, Imperial College London, Cyclotron Building, Hammersmith Hospital, Du Cane Road, LondonW12 0NN, UK
P. Edison
Affiliation:
MRC Clinical Science Centre, Imperial College London, Cyclotron Building, Hammersmith Hospital, Du Cane Road, LondonW12 0NN, UK
T. Dannhauser
Affiliation:
Department of Mental Health Sciences, University College London, Windeyer Building, 46, Cleveland Street, LondonW1T 4JF, UK
D.J. Brooks
Affiliation:
MRC Clinical Science Centre, Imperial College London, Cyclotron Building, Hammersmith Hospital, Du Cane Road, LondonW12 0NN, UK
Z. Walker
Affiliation:
Department of Mental Health Sciences, University College London, Windeyer Building, 46, Cleveland Street, LondonW1T 4JF, UK
*
*Corresponding author. Tel.: +44 01279 827893; fax: +44 01 992 571089. E-mail address: [email protected] (J. Rodda).
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Abstract

People with Subjective Cognitive Impairment (SCI) may be at increased risk of dementia. In this study we examined amyloid load in 5 SCI subjects and 14 controls using PIB PET scanning. One SCI subject had significantly increased PIB retention in the cortical areas of interest. Larger, longitudinal studies are indicated.

Type
Short communication
Copyright
Copyright © Elsevier Masson SAS 2010

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