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Viabilidad de la farmacoterapia en trastornos del espectro afectivo relacionados con el VIH: un ensayo abierto con fluvoxamina

Published online by Cambridge University Press:  12 May 2020

P. Perretta ,
C. Nisita ,
E. Zaccagnini ,
C. Lorenzetti ,
A. Nuccorini ,
G. B. Cassano ,
D. M. McNair  and
H. S. Akiskal
P. Perretta
Affiliation:
Clínica Psiquiátrica 1, Universidad de Pisa, Pisa, Italia
C. Nisita
Affiliation:
Clínica Psiquiátrica 1, Universidad de Pisa, Pisa, Italia
E. Zaccagnini
Affiliation:
Clínica Psiquiátrica 1, Universidad de Pisa, Pisa, Italia
C. Lorenzetti
Affiliation:
Clínica Psiquiátrica 1, Universidad de Pisa, Pisa, Italia
A. Nuccorini
Affiliation:
Centro para la Vigilancia del SIDA de Pisa, Pisa, Italia
G. B. Cassano
Affiliation:
Clínica Psiquiátrica 1, Universidad de Pisa, Pisa, Italia
D. M. McNair
Affiliation:
Profesor Emérito, Universidad de Boston, EEUU;
H. S. Akiskal
Affiliation:
Universidad de California en San Diego, San Diego, EEUU
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Resumen

En un estudio abierto, evaluamos la viabilidad de utilizar un antidepresivo serotoninérgico (fluvoxamina) entre pacientes con VIH tratados por trastornos adaptativos, depresivos mayores y otros trastornos afectivos relacionados con el SIDA. Se realizó el seguimiento de 35 pacientes seropositivos (22 hombres y 13 mujeres) con las condiciones anteriores durante un periodo mínimo de cuatro semanas. Al final del tratamiento, un gran número de pacientes (77%) mostraba una mejoría acusada. Los síntomas “nucleares” depresivos y de ansiedad remitieron, mientras que los “somáticos” parecían menos sensibles al tratamiento. El tratamiento tuvo que ser interrumpido prematuramente debido a efectos secundarios en sólo dos pacientes (6%).

Keywords

fluvoxaminatratamientopacientes con VIHtrastornos del espectro afectivotrastorno orgánico del estado de animo
Type
Artículo original
Information
European Psychiatry (Ed. Española) , Volume 3 , Issue 3 , June 1996 , pp. 168 - 174
Copyright
Copyright © European Psychiatric Association 1996

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