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Terapia neuroléptica a dosis bajas y efectos secundarios extrapiramidales en esquizofrenia: un análisis del tamaño del efecto

Published online by Cambridge University Press:  12 May 2020

C. Barbui  and
B. Saraceno
C. Barbui
Affiliation:
Laboratorio de Epidemiología y Psiquiatría Social, Instituto “Mario Negri” para la Investigación Farmacológica, Milán, Italia
B. Saraceno
Affiliation:
Laboratorio de Epidemiología y Psiquiatría Social, Instituto “Mario Negri” para la Investigación Farmacológica, Milán, Italia
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Resumen

Se realizó un metaanálisis de los trabajos publicados para cuantificar la eficacia de la terapia neuroléptica a dosis bajas en la reducción de los efectos secundarios extrapiramidales en pacientes esquizofrénicos. Un régimen de dosis bajas entre 50- 100 mg de equivalentes de clorpromacina, en comparación con un régimen de dosis estándar entre 200-500 mg, redujo los efectos secundarios extrapiramidales en un 0,30 (± 0,12) de desviación típica, lo que sólo es un efecto limitado.

Keywords

neurolépticodosis bajasefectos secundarios
Type
Comunicación breve
Information
European Psychiatry (Ed. Española) , Volume 4 , Issue 5 , July 1997 , pp. 323 - 326
Copyright
Copyright © European Psychiatric Association 1997

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Footnotes

Barbui C, Saraceno B. Low-dose neuroleptic therapy and extrapyramidal side effects in schizophrenia: an effect size analysis. Eur Psychiatry 1996; 11: 412-415

References

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