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¿Merece la pena cambiar de antipsicóticos convencionales a atípicos a pacientes ambulatorios esquizofrénicos clínicamente estables con síntomas residuales, efectos secundarios, o ambas cosas, de leves a moderados? Un estudio prospectivo distribuido al azar con olanzapina

Published online by Cambridge University Press:  12 May 2020

Björn Appelberg ,
Katinka Tuiskua  and
Grigori Joffe
Björn Appelberg
Affiliation:
Departamento de Psiquiatría, Hospital Central de la Universidad de Helsinki, POB 590, 00029 Hus, Finlandia.
Grigori Joffe
Affiliation:
Hospital Psiquiátrico de Kellokoski, Finlandia.
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Resumen

Se distribuyó al azar a cincuenta pacientes ambulatorios esquizofrénicos clínicamente estables que sufrían de síntomas esquizofrénicos residuales, efectos secundarios neurológicos o ambas cosas para que continuaran su(s) neuroléptico(s) convencional(es) o lo(s) cambiaran por olanzapina. Después de doce semanas, los pacientes con olanzapina mostraban mejoría significativa en los efectos secundarios neurológicos y los síntomas psicóticos, comparado con los pacientes con antipsicóticos convencionales.

Keywords

EsquizofreniaPacientes ambulatoriosEnsayo distribuido al azarAntipsicóticos atípicosOlanzapina
Type
Comunicación breve
Information
European Psychiatry (Ed. Española) , Volume 12 , Issue 4 , May 2005 , pp. 247 - 249
Copyright
Copyright © European Psychiatric Association 2005

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Footnotes

Appelberg B., Tuisku K, Joffe G. Is it worth while changing clinically stable schizophrenic out-patients with mild to moderate residual symptoms and/or side effects from conventional to atypical antipsychotics? A prospective, randomised study with olanzapine. Eur Psychiatry 2004;19:516- 518.

References

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