Hostname: page-component-586b7cd67f-t8hqh Total loading time: 0 Render date: 2024-11-26T22:33:45.708Z Has data issue: false hasContentIssue false

Índice de masa corporal y funcionamiento psicosocial en pacientes con esquizofrenia de larga duración: resultados del proyecto DSP

Published online by Cambridge University Press:  12 May 2020

Raimo K.R. Salokangas
Affiliation:
Departamento de Psiquiatría, Clínica de Psiquiatría, Universidad de Turku, Hospital Central de la Universidad de Turku, Clínica Psiquiátrica Turku, Kiinamyllynkatu 4-8, FI-20520Turku, Finlandia
Teija Honkonen
Affiliation:
Instituto Finlandés de Salud Ocupacional, Topeliuksenkatu 41aA, FI-00250Helsinki, Finlandia
Eija Stengård
Affiliation:
Centro Nacional de Investigación y Desarrollo para la Salud y Bienestar, Salud y Servicios Sociales. P.O. Box 220, FI-0053IHelsinki, Finlandia
Jarmo Hietala
Affiliation:
Departamento de Psiquiatría, Universidad de Turku, FI-20700Turku, Finlandia
Get access

Resumen

Objetivo

El estudio evaluó la asociación entre el índice de masa corporal (IMC) y el funcionamiento psicosocial en hombres y mujeres con esquizofrenia de larga duración.

Método

Se entrevistaron 722 pacientes con esquizofrenia de larga duración tres años después de recibir el alta del hospital. Se registraron el peso y la altura y se recogieron datos sobre antecedentes, evolución de la enfermedad, funcionamiento psicosocial (Escala de Evaluación Global; GAS), comportamiento saludable, dosis diarias de neurolépticos y síntomas psiquiátricos.

Resultados

El IMC se correlacionó significativamente con las puntuaciones de GAS en hombres (r = 0,202, p = 0,000) pero no en mujeres. En hombres, el IMC se asoció significativamente (p = 0,005) con las puntuaciones de GAS incluso teniendo en cuenta los efectos de los síntomas psiquiátricos y otras variables contaminantes.

Conclusiones

En hombres pero no en mujeres con esquizofrenia de larga duración, el IMC bajo se asocia con funcionamiento psicosocial deficiente. Se cree que en hombres con esquizofrenia, el IMC bajo puede ser un indicador de funcionamiento psicosocial deficiente.

Type
Artículo original
Copyright
Copyright © European Psychiatric Association 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bibliografía

Alanen, YO, Räkkäläinen, V, Laakso, J, Rasimus, R, Kaljonen, A. Towards need-specific treatment of schizophrenic psychoses. Heidelberg: Springer-Verlag; 1986.CrossRefGoogle ScholarPubMed
Allison, DB, Casey, DE. Antipsychotic-induced weight gain: a review of the literature. J Clin Psychiatry 2001 ;62(Suppl 7):2231.Google ScholarPubMed
Allison, DB, Fontaine, KR, Heo, M, Mentore, JL, Cappelleri, JC, Chandler, LP, et al. The distribution of body mass index among individuais with and without schizophrenia. J Clin Psychiatry 1999;60:215–20.CrossRefGoogle Scholar
Angermeyer, MC, Kühn, L, Goldstein, JM. Gender and the course of schizophrenia: differences in treated outcomes. Schizophr Bull 1990;16:293307.CrossRefGoogle ScholarPubMed
Basson, BR, Kinon, BJ, Taylor, CC, Szymanski, KA, Gilmore, JA, Tollefson, GD. Factors influencing acute weight change in patients with schizophrenia treated with olanzapine, haloperidol, or risperidone. J Clin Psychiatry 2001;62:231–8.CrossRefGoogle ScholarPubMed
Endicott, J, Spitzer, RL, Fieis, JL, Cohen, J. The Global Assessment Scale. A procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry 1976;33:766–71.CrossRefGoogle ScholarPubMed
Harman, HH. Modem factor analysis. Chicago: University of Chicago Press; 1976.Google Scholar
Horrobin, DF. The membrane phospholibid hypothesis as a biochemical basis for the neurodevelopmental concept of schizophrenia. Schizophr Res 1998;30:193208.CrossRefGoogle ScholarPubMed
Kay, SR, Opler, LA, Fiszbein, A. Positive and negative syndrome scale (PANSS) rating manual. Bronx: Bronx Psychiatric Center; 1986.Google Scholar
Kinon, BJ, Basson, BR, Gilmore, JA, Tollefson, GD. Long-term olanzepine treatment: weight change and weight-related health factors in schizophrenia. J Clin Psychiatry 2001;62:92100.CrossRefGoogle Scholar
Leung, A, Chue, P. Sex differences in schizophrenia, a review of the literature. Acta Psychiatr Scand Suppl 2000;401:338.CrossRefGoogle ScholarPubMed
Lieberman, J, Chakos, M, Wu, H, Alvir, J, Hoffman, E, Robinson, D, et al. Longitudinal study of brain morphology in first episode schizophrenia. Biol Psychiatry 2001;49:487–99.CrossRefGoogle ScholarPubMed
McElroy, SL, Kotwal, R, Malhotra, S, Nelson, EB, Keck, PE, Nemeroff, CB. Are mood disorders and obesity related? A review for the mental health professionals. J Clin Psychiatry 2004;65:634–51.CrossRefGoogle Scholar
Melkersson, KI, Hulung, AL, Brismar, KE. Elevated levels of insulin, leptin, and blood lipids in olanzepine-treated patients with schizophrenia or related psychoses. J Clin Psychiatry 2000;61:742–9.CrossRefGoogle ScholarPubMed
Meltzer, HY, Perry, E, Jayathilake, K. Clozapine-induced weight gain predicts improvement in psychopathology. Schizophr Res 2003;59:1927.CrossRefGoogle ScholarPubMed
Murray, RM, Van Os, J. Predictors of outcome in schizophrenia. J Clin Psychopharmacol 1998;18(Suppl l):2S4.CrossRefGoogle Scholar
Myers, A, Rosen, J. Obesity stigmatization and coping: relation to mental health symptoms, body image, and self-esteem. Int J Obes Relat Metab Disord 1999;23:221–30.CrossRefGoogle ScholarPubMed
Newcomer, JW. Second-generation (atypical) antipsychotics and metabolic effects: a comprebensive literature review. CNS Drugs 2005;19(Suppl l):l-93.CrossRefGoogle ScholarPubMed
Salokangas, RKR, Honkonen, T, Stengård, E, Koivisto, A-M. Symptom dimensions and their association with outcome and treatment setting in long-term schizophrenia. Results of the DSP project. Nord J Psychiatry 2002;56:319–27.CrossRefGoogle ScholarPubMed
Salokangas, RKR, Stengård, E, Honkonen, T, Koivisto, A-M, Saarinen, S. Sairaalasta yhteiskuntaan. Seurantatutkimus sairaalasta kotiuttamisen vaikutuksista skitsofreniapotilaan elämään ja hoitotilanteeseen (In Finnish). Helsinki: STAKES; 2000. Raportteja 248.Google Scholar
Salokangas, RKR. Symptom dimensions and outcome in schizophrenia. World Psychiatry 2003;2:172–8.Google Scholar
Salokangas, RKR. Prognostic implications of the sex of schizophrenic patients. Br J Psychiatry 1983;142:145–51.CrossRefGoogle ScholarPubMed
Seeman, MV. Current outcome in schizophrenia: women vs men. Acta Psychiatr Scand 1986;73:609–17.CrossRefGoogle ScholarPubMed
Taylor, DM, McAskill, R. Atypical antipsychotics and weight gain—a systematic review. Acta Psychiatr Scand 2000;101:416–32.CrossRefGoogle ScholarPubMed