Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-19T04:35:06.676Z Has data issue: false hasContentIssue false
  • English
  • Français

Predicción de la duración de la psicosis antes de la primera admisión

Published online by Cambridge University Press:  12 May 2020

H. Verdoux ,
C. Bergey ,
F. Assens ,
F. Abalan ,
B. Gonzales ,
P. Pauillac ,
O. Fournet ,
F. Liraud ,
J. P. Beaussier  and
C. Gaussares
...Show all authors
H. Verdoux
Affiliation:
Departamente de Psiquiatría, Universidad Victor Segalen Bordeaux Hospital de Charles Perrens, Bordeaux, Francia
C. Bergey
Affiliation:
Hospital de Charles Perrens, Bordeaux, Francia
F. Assens
Affiliation:
Hospital de Charles Perrens, Bordeaux, Francia
F. Abalan
Affiliation:
Hospital de Charles Perrens, Bordeaux, Francia
B. Gonzales
Affiliation:
Hospital de Charles Perrens, Bordeaux, Francia
P. Pauillac
Affiliation:
Departamente de Psiquiatría, Universidad Victor Segalen Bordeaux Hospital de Charles Perrens, Bordeaux, Francia
O. Fournet
Affiliation:
Departamente de Psiquiatría, Universidad Victor Segalen Bordeaux Hospital de Charles Perrens, Bordeaux, Francia
F. Liraud
Affiliation:
Hospital de Charles Perrens, Bordeaux, Francia
J. P. Beaussier
Affiliation:
Hospital de Charles Perrens, Bordeaux, Francia
C. Gaussares
Affiliation:
Hospital de Charles Perrens, Bordeaux, Francia
B. Etchegaray
Affiliation:
Hospital de Charles Perrens, Bordeaux, Francia
M. Bourgeois
Affiliation:
Departamente de Psiquiatría, Universidad Victor Segalen Bordeaux Hospital de Charles Perrens, Bordeaux, Francia
J. van Os
Affiliation:
Universidad de Maastricht, Países Bajos
Get access

Abstract

Resumen:

Evaluar los factores que predicen el intervalo entre el comienzo de los síntomas psicóticos y la primera admisión en una muestra de la población.

Método:

Se comprobó de manera estandarizada la duración de la psicosis antes de la admisión para 59 pacientes consecutivos ingresados por primera vez que presentaban síntomas psicóticos.

Resultados:

La mediana de la duración de la psicosis antes de la admisión fue 3 meses (rango intercuartil: 0,5-14). La historia familiar de hospitalización psiquiátrica (razón de probabilidad [RP] = 12,1, intervalo de confianza [IC] de 95% = 1,15-97,0, P = 0,02), el nivel educativo bajo (RP = 7,7, IC 95% = 1,0-50,0, P = 0,05), el ajuste global malo en el año anterior (RP = 0,93, IC 95% = 0,86- 0,99, P = 0,04) y una gravedad global mayor de la enfermedad en la admisión (RP = 4,0, IC 95% = 0,87-18,3, P = 0,07) predijeron independientemente un intervalo ≥ 3 meses.

Conclusión:

Ya que se sabe también que estos factores predicen una evolución mala, nuestros resultados indican que la asociación entre la duración de la psicosis no tratada y el mal pronóstico puede estar mediada, al menos en parte, por estas variables demográficas y clínicas.

Keywords

primera admisiónduración de la psicosisfactores predictivosevolución
Type
Artículo Original
Information
European Psychiatry (Ed. Española) , Volume 6 , Issue 3 , April 1999 , pp. 162 - 169
Copyright
Copyright © European Psychiatric Association 1999

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bibliografía

American Psychiatric Association. DSM-III-R. Diagnostic and Statistical Manual of Mental Disorders. 3rd ed, Revised. Washington, DC: APA; 1987.Google Scholar
American Psychiatric Association. DSM-IV. Diagnostic and Statistical Manual of Mental Disorders. 4th ed, Revised, Washington, DC: APA; 1994.Google Scholar
Beiser, M, Erickson, D, Fleming, JAE, Iacono, WG. Establishing the onset of psychotic illness. Am J Psychiatry 1993; 150: 1349–54.Google ScholarPubMed
Crow, TJ, McMillan, JF, Johnson, AL, Johnstone, EC. A randomised controlled trial of prophylactic neuroleptic treatment. Br J Psychiatry 1986; 148: 120–7.CrossRefGoogle ScholarPubMed
Endicott, J, Andreasen, N, Spitzer, RL. Family History- Research Diagnostic Criteria (3rd Ed). Biometrics Research. New York: New York State Psychiatric Institute; 1978.Google Scholar
Gupta, S, Andreasen, NC, Ardnt, S, Flaum, M, Hubbard, W, Ziebell, S.The IOWA longitudinal study of recent onset psychosis; one year follow-up of first episode patients. Schizophr Res 1997; 23: 1–13.CrossRefGoogle ScholarPubMed
Guy, W.Assessment Manual for Psychopharmacology. National Institute of Mental Health, Early Clinical Drug Evaluation Unit; 1976.Google Scholar
Haas, GK, Sweeney, JA. Premorbid and onset features of first-episode schizophrenia. Schizophr Bull 1992; 18: 373–86.CrossRefGoogle ScholarPubMed
Häfner, H, an der Heiden, W, Behrens, S, Gattaz, WF, Hambrecht, M, Loffler, Wet al.Causes and consequences of the gender differences in age at onset of schizophrenia. Schizophr Bull 1998; 24: 99–113.CrossRefGoogle Scholar
Häfner, H, Riechler-Rossler, A, Hambrecht, M, Maurer, K, Meissner, S, Schmidtke, Aet al.IRAOS: an instrument for the assessment of onset and early course of schizophrenia. Schizophr Res 1992; 6: 209–23.CrossRefGoogle ScholarPubMed
Kay, SR, Fizbein, A, Opler, LA. The positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 1987; 13: 261–76.CrossRefGoogle Scholar
Kendler, KS, Tsuang, MT. Outcome and familial psychopathology in schizophrenia. Arch Gen Psychiatry 1988; 45: 338–46.CrossRefGoogle Scholar
Larsen, TK, McGlashan, TH, Moe, LC. First-episode schizophrenia: I. Early course parameters. Schizophr Bull 1996; 22: 241–56.CrossRefGoogle ScholarPubMed
Lecrubier, Y, Sheehan, DV, Weiller, E, Amorin, P, Bonora, I, Sheehan, KHet al.The Mini International Neuropsychiatric Interview (MINI). A. short diagnostic structured interview: reliability and validity according to the CIDI. Eur Psychiatry 1997; 12: 224–31.CrossRefGoogle Scholar
Loebel, AD, Lieberman, JA, Alvir, JM, Mayerhoff, DI, Geisler, SH, Szymanski, SR. Duration of psychosis and outcome in first-episode schizophrenia. Am J Psychiatry 1992; 149: 1183–8.Google ScholarPubMed
McGlashan, TH, Johannessen, JO. Early detection and intervention with schizophrenia: rationale. Schizophr Bull 1996; 22: 201–22.CrossRefGoogle ScholarPubMed
McKenzie, K, van Os, J, Fahy, T, Jones, P, Harvey, I, Toone, Bet al.Psychosis with good prognosis in Afro-Caribbean people now living in the United Kingdom. BMJ 1995; 311: 1325–8.CrossRefGoogle ScholarPubMed
Maurer, K, Häfner, H. Methodological aspects of onset assessment in schizophrenia. Schizophr Res 1995; 15: 265–76.CrossRefGoogle Scholar
Norusis, MJ. SPSS for Windows 5.0.1. Chicago: SPPS Inc; 1992.Google Scholar
Ram, R, Bromet, EJ, Eaton, WW, Pato, C, Schwartz, JE. The natural course of schizophrenia: a review of first-admission studies. Schizophr Bull 1992; 18: 185–207.CrossRefGoogle ScholarPubMed
Vaglum, P.Earlier detection and intervention in schizophrenia: unsolved questions. Schizophr Bull 22; 1996: 347–51.Google Scholar
van Os, J, Fahy, TA, Jones, P, Harvey, I, Sham, P, Lewis, Set al.Psychopathological syndromes in the functional psychoses. Associations with course and outcome. Psychol Med 1995; 26:161–76.CrossRefGoogle Scholar
van Os, J, Takei, N, Verdoux, H, Delespaul, P.Eariy detection of schizophrenia. Br J Psychiatry 1997; 170–579.Google Scholar
Verdoux, H, Van Os, J, Sham, PC, Jones, PB, Gilvarry, K, Murray, RM. Does familiality predispose to both emergence and persistence of psychosis? A follow-up study. BrJ Psychiatry 1996; 168: 620–6.CrossRefGoogle ScholarPubMed
Waddington, JL, Youssef, HA, Kinsella, A.Sequential cross-sectional and 10-years prospective study of severe negative symptoms in relation to duration of initially untreated psychosis in chronic schizophrenia. Psychol Med 25; 1995: 849–57.Google Scholar
Wyatt, RJ. Neuroleptics and the natural course of schizophrenia. Schizophr Bull 1991; 17: 325–51.CrossRefGoogle ScholarPubMed
Wyatt, RJ, Green, MF, Turna, AH. Long-term morbidity associated with delayed treatment of first admission schizophrenic patients: a re-analysis of the Camarillo State Hospital data. Psychol Med 1997; 27: 261–8.CrossRefGoogle ScholarPubMed