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¿Ha habido una disminución en la prevalencia de los trastornos del estado de ánimo en los individuos seropositivos al VIH desde la introductión de la terapia de combinación?

Published online by Cambridge University Press:  12 May 2020

A. Alciati ,
F. Starace ,
B. Scaramelli ,
M. Campaniello ,
B. Adriani ,
C. Mellado  and
A. Cargnel
A. Alciati
Affiliation:
Departamento de Psiquiatría, Hospital L Sacco, Milán, ltalia;
F. Starace
Affiliation:
Servicio de Consulta Psiquiátrica, Hospital D. Cotugno θ Instituto de Psiquiatría, Universidad de Nápoles, SUN, ltalia;
B. Scaramelli
Affiliation:
Departamento de Psiquiatría, Hospital L Sacco, Milán, ltalia;
M. Campaniello
Affiliation:
Segundo Departamento de Enfermedades Infecciosas, Hospital L Sacco, Milán, ltalia
B. Adriani
Affiliation:
Segundo Departamento de Enfermedades Infecciosas, Hospital L Sacco, Milán, ltalia
C. Mellado
Affiliation:
Segundo Departamento de Enfermedades Infecciosas, Hospital L Sacco, Milán, ltalia
A. Cargnel
Affiliation:
Segundo Departamento de Enfermedades Infecciosas, Hospital L Sacco, Milán, ltalia
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Resumen

Proposito:

El propósito de este estudio era evaluar la prevalencia de trastornos del estado de ánimo actuales en pacientes seropositivos al VIH tratados con terapia farmacológica antirretrovírica combinada que incluía o no inhibidores de la proteasa.

Sujetos y métodos:

Se evaluó una muestra aleatoria de 90 sujetos que acudieron consecutivamente entre el 1 de febrero y el 31 de julio de 1998 a la unidad ambulatoria del Segundo Departamento de Enfermedades Infecciosas del Hospital “L. Sacco” en Milán por medio de la Entrevista Clínica Estructurada para el DSM-III-R (SCID) y la Escala de Autoevaluación de la Depresión de Zung (ZSDS).

Resultados:

Se clasificó a un 23,3% de sujetos en el estadio A de la CDC, a un 32,3% en el estadio B y a un 44,4% en el estadio C. Se encontro un diagnostico psiquiátrico del DSM-III-R de trastorno del estado de ánimo actual en 4,4% de la muestra seleccionada (distimia: 2,2%; trastorno adaptativo con estado de ánimo deprimido: 2,2%).

Conclusiones:

El efecto directo e indirecto de las nuevas terapias de combinación, los cambios epidemiológicos en los grupos sociales afectados por el VIH y las posibles modificaciones en la perceptión social de las personas con infección por VIH pueden explicar, al menos en parte, la disminución de la prevalencia de trastornos del estado de ánimo actuales observada en nuestro estudio comparado con las tasas de prevalencia comunicadas en la época anterior a la terapia antirretrovírica muy activa (TARMA).

Keywords

depresiónTARMA/VIHtrastornos del estado de ánimoestudio de la prevalencia
Type
Artículo Original
Information
European Psychiatry (Ed. Española) , Volume 9 , Issue 3 , April 2002 , pp. 158 - 163
Copyright
Copyright © European Psychiatric Association 2002

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