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Identifiability of stochastically modelled reaction networks
Published online by Cambridge University Press: 15 February 2021
Abstract
Chemical reaction networks describe interactions between biochemical species. Once an underlying reaction network is given for a biochemical system, the system dynamics can be modelled with various mathematical frameworks such as continuous-time Markov processes. In this manuscript, the identifiability of the underlying network structure with a given stochastic system dynamics is studied. It is shown that some data types related to the associated stochastic dynamics can uniquely identify the underlying network structure as well as the system parameters. The accuracy of the presented network inference is investigated when given dynamical data are obtained via stochastic simulations.
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- Information
- European Journal of Applied Mathematics , Volume 32 , Special Issue 5: 30th Anniversary Special Issue , October 2021 , pp. 865 - 887
- Copyright
- © The Author(s), 2021. Published by Cambridge University Press
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