Due to the recent interest shown by astronomers towards the Antarctic Plateauas a potential site for large astronomical facilities, we assistedin the last years to a strengthening of site testing activities in this region, particularly at Dome C. Most of the results collected so far concern meteorologic parameters and optical turbulence measurements based on different principles using different instruments. At present we have several elements indicating that, above the first $20{-}30$ m, the quality of the optical turbulence above Dome C is better than above whatever other site in the world. The challenging question, crucial to know which kind of facilities to build on, is to establish how much better the Dome C is than a mid-latitude site. In this contribution we will provide some complementary elements and strategies of analysis aiming to answer to this question. We will try to concentrate the attention on critical points, i.e. open questions that still require explanation/attention.