Hostname: page-component-78c5997874-94fs2 Total loading time: 0 Render date: 2024-11-19T12:45:21.338Z Has data issue: false hasContentIssue false

Is there a continuum of psychotic experiences in the general population?

Published online by Cambridge University Press:  11 October 2011

Jim Van Os*
Affiliation:
Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, The Netherlands, and Division of Psychological Medicine, Institute of Psychiatry, London, UK
*
Address for correspondence: Professor J. van Os, Department of Psychiatry and Neuropsychology, Section of Social Psychiatry and Psychiatric Epidemiology, PO Box 616 (DRT10), 6200 MD Maastricht (The Netherlands). Fax: 31-43-387.5444

Abstract

Summary

Aims - Schizophrenia is a severe mental illness that affects 1% of the population. The diagnosis is made according to current diagnostic systems of DSM-1V (American Psychiatric Association, 1994) and ICD-10 (World Health Organisation, 1992), on the basis of characteristic ‘positive’ and ‘negative’ symptoms. The traditional model assumes a categorical view of the schizophrenia syndrome and its core symptoms, in which differences between psychotic symptoms and their normal counterparts are considered to be qualitative. An alternative, dimensional approach assumes that schizophrenia is not a discrete illness entity, but that psychotic symptoms differ in quantitative ways from normal experiences and behaviours. This paper reviews evidence for the continuity of psychotic symptoms with normal experiences, focusing on the symptoms of hallucinations and delusions. Methods - A qualitative review of the relevant literature. Results - The literature suggests that although current epidemiological approaches yield substantial evidence for a continuum view, it is rarely interpreted as such. Conclusions - The traditional concept ofschizophrenia as a homogeneous disease entity has become outdated and is in dire need of a more valid and clinically useful successor.

Declaration of Interests

Support has been received in the last two years from the Dutch Research Council, The Dutch Ministry of Health, Maastricht University, The Dutch Brain Society, ZON-MW, The Province of Limburg, The Council of Maastricht, Eli Lilly, Janssen-Cilag, Pfizer, Astra-Zeneca and Bristol Meyer Squibb. None of these funding sources represents a conflict of interest in relation to this article.

Type
Invited Paper
Copyright
Copyright © Cambridge University Press 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

American Psychiatric Association (1994): Diagnostic Criteria from the DSM-IV. American Psychiatric Association: Washington, DC.Google Scholar
Anderson, J., Huppert, F. & Rose, G. (1993). Normality, deviance and minor psychiatric morbidity in the community. Psychiatric Medicine 23, 475485.Google ScholarPubMed
Bak, M., Van der Spil, F., Gunther, N., Radstake, S., Delespaul, P. & van Os, J. (2001a). Macs II. Does coping enhance subjective control over symptoms? Acta Psychiatrica Scandinavica 103, 460464.CrossRefGoogle ScholarPubMed
Bak, M., Van der Spil, F., Gunther, N., Radstake, S., Delespaul, P. & van Os, J. (2001b). Macs-I. Maastricht Assessment of coping strategies: a brief instrument to assess coping with psychotic symptoms. Acta Psychiatrica Scandinavica 103, 453459.CrossRefGoogle ScholarPubMed
Bak, M., Hanssen, M., Bijl, R.V., Vollebergh, W., Delespaul, P. & van Os, J. (submitted for publication). When does experience of psychosis result in need for care? A prospective general population study.Google Scholar
Barrett, T.R. & Eysenck, J.B. (1992). Verbal hallucinations in normals, I:People who hear voices. Applied Cognitive Psychology 6, 379387.CrossRefGoogle Scholar
Bentall, R.P. & Slade, P.D. (1985). Reality testing and auditory hallucinations: a signal detection analysis. British Journal of Clinical Psychology 24, 159169.CrossRefGoogle ScholarPubMed
Bentall, R.P., Claridge, G.S. & Slade, P.D. (1989). The multidimensional nature of schizotypal traits: a factor analytic study with normal subjects. British Journal of Clinical Psychology 28, 363375.CrossRefGoogle ScholarPubMed
Bentall, R.P., Kinderman, P. & Kaney, S. (1994). The self, attributional processes and abnormal beliefs: towards a model of persecutory delusions. Behavior Research Therapy 32, 331341.CrossRefGoogle Scholar
Bijl, R.V., van Zessen, G., Ravelli, A., de Rijk, C. & Langendoen, Y. (1998). The Netherlands Mental Health Survey and Incidence Study (NEMESIS): objectives and design. Social Psychiatry and Psychiatric Epidemiology 33, 581586.CrossRefGoogle ScholarPubMed
Bilder, R.M., Mukherjee, S., Rieder, R.O. & Pandurangi, A.K. (1985). Symptomatic and neuropsychological components of defect states. Schizophrenia Bulletin 11, 409419.CrossRefGoogle ScholarPubMed
Carr, V. (1988). Patients' techniques for coping with schizophrenia: an exploratory study. British Journal of Medical Psychology 61, 339352.CrossRefGoogle ScholarPubMed
Chapman, L.J., Chapman, J.P. & Raulin, M.L. (1978). Body-image aberration in schizophrenia. Journal of Abnormal Psychology 87, 399407.CrossRefGoogle ScholarPubMed
Chapman, L.J., Chapman, J.P., Kwapil, T.R., Eckblad, M. & Zinser, M.C. (1994). Putatively psychosis-prone subjects 10 years later. Journal of AbnormalPsychology 103, 171183.Google ScholarPubMed
Claridge, G.S. (1990). Can a disease model of schizophrenia survive? In Reconstructing Schizophrenia (ed. Bentall, R.P.). Routledge: London.Google Scholar
Claridge, G. (1994). Single indicator of risk for schizophrenia: probable fact or likely myth? Schizophrenia Bulletin 20, 151168.CrossRefGoogle ScholarPubMed
Claridge, G. (1997a). Final remarks and future directions. In Schizotypy. Implications for Illness and Health (ed. Claridge, G.), pp. 301317. Oxford University Press: Oxford.CrossRefGoogle Scholar
Claridge, G. (1997b). Theoretical background and issues. In Schizotypy. Implications for Illness and Health (ed. Claridge, G.), pp. 319. Oxford University Press: Oxford.CrossRefGoogle Scholar
Claridge, G. & Broks, P. (1984). Schizotypy and hemisphere function: I Theoretical considerations and the measurment of schizotypy. Personality and Individual Differences 5, 633648.CrossRefGoogle Scholar
Claridge, G., McCreery, C., Mason, O., Bentall, R., Boyle, G., Slade, P. & Popplewell, D. (1996). The factor structure of “schizotypal’ traits: a large replication study. British Journal of Clinical Psychology 35, 103115.CrossRefGoogle ScholarPubMed
Cox, D. & Cowling, P. (1989). Are you Normal? Tower Press: London.Google Scholar
Driessen, G., Gunther, N., Bak, M., van Sambeek, M. & van Os, J. (1998). Characteristics of early- and late-diagnosed schizophrenia: implications for first-episode studies. Schizophrenia Research 33, 2734.CrossRefGoogle ScholarPubMed
Eaton, W.W., Romanoski, A., Anthony, J.C. & Nestadt, G. (1991). Screening for psychosis in the general population with a self-report interview. Journal of Nervous and Mental Disease 179, 689693.CrossRefGoogle ScholarPubMed
Eysenck, H.J. & Eysenck, S.B.G. (1973). The Manual of the Personality Questionnaire. Unpublished Manuscript.Google Scholar
Freeman, D., Garety, P., Fowler, D., Kuipers, E., Dunn, G., Bebbington, P. & Hadley, C. (1998). The London-East Anglia randomized controlled trial of cognitive- behaviour therapy for psychosis. IV: Selfesteem and persecutory delusions. BritishJournal of Clinical Psychology 37, 415430.CrossRefGoogle ScholarPubMed
Frith, C.D. & Corcoran, R. (1996). Exploring ‘theory of mind’ in people with schizophrenia. Psychological Medicine 26, 521530.CrossRefGoogle ScholarPubMed
Galdos, P.M., van Os, J.J. & Murray, R.M. (1993). Puberty and the onset of psychosis. Schizophrenia Research 10, 714.CrossRefGoogle ScholarPubMed
Garety, P.A. & Freeman, D. (1999). Cognitive approaches to delusions: a critical review of theories and evidence. British Journal of Clinical Psychology 38, 113154.CrossRefGoogle ScholarPubMed
Garety, P. & Hemsley, D.R. (1994). Delusions. Investigations into the Psychology of Delusional Reasoning, Vol 36. Oxford University Press: Oxford.Google Scholar
Garety, P.A., Hemsley, D.R. & Wessely, S. (1991). Reasoning in deluded schizophrenic and paranoid patients. Biases in performance on a probabilistic inference task. Journal of Nervous Mental Diseases 179, 194201.CrossRefGoogle ScholarPubMed
Garety, P., Kuipers, E., Fowler, D., Freeman, D. & Bebbington, P. (2001). A cognitive model of the positive symptoms of psychosis. Psychological Medicine 31, 189195.CrossRefGoogle ScholarPubMed
Goldberg, D. & Huxley, P. (1980). Mental Illness in the Community. Tavistock Publications: London.Google Scholar
Gruzelier, J.H. (1996). The factorial structure of schizotypy: Part I. Affinities withsyndromes of schizophrenia. Schizophrenia Bulletin 22, 611620.CrossRefGoogle ScholarPubMed
Häfner, H. (1988). What is schizophrenia? Changing perspectives in epidemiology. European Archives of Psychiatry and Neurological Sciences 238, 6372.CrossRefGoogle ScholarPubMed
Häfner, H. (1989a). Application of epidemiological research toward a model for the etiology of schizophrenia. Schizophrenia Research 2, 375383.CrossRefGoogle Scholar
Häfner, H. (1989b). [Is schizophrenia a disease? Epidemiologic data and speculative conclusions]. Nervenarzt 60, 191199.Google ScholarPubMed
Häfner, H., Riecher, A., Maurer, K., Loffler, W., Munk-Jørgensen, P. & Stromgren, E. (1989). How does gender influence age at first hospitalization for schizophrenia? A transnational case register study. Psychological Medicine 19, 903918.CrossRefGoogle ScholarPubMed
Häfner, H., Maurer, K., Loffler, W. & Riecher-Rossler, A. (1991). [Schizophrenia and age]. Nervenarzt 62, 536548.Google ScholarPubMed
Häfner, H., Maurer, K., Loffler, W., Fatkenheuer, B., an der Heiden, W., Riecher Rossler, A., Behrens, S. & Gattaz, W.F. (1994). The epidemiology of early schizophrenia. Influence of age and gender on onset and early course. British Journal of Psychiatry, Suppl. 23, 2938.CrossRefGoogle ScholarPubMed
Häfner, H., Hambrecht, M., Loffler, W., Munk-Jørgensen, P. & Riecher-Rossler, A. (1998). Is schizophrenia a disorder of all ages? A comparison of first episodes and early course across the life-cycle. Psychological Medicine 28, 351365.CrossRefGoogle Scholar
Hanssen, M.Bijl, R., Vollebergh, W. & Van Os, J. (2003). Psychotic symptoms in the general population as a diagnostic test for DSMIII-R psychotic disorders. Ada Psychiatrica Scandinavica 107, 369377.CrossRefGoogle Scholar
Jackson, M.C. (1997). Benign schizotypy? The case of spiritual experience. InSchizotypy. Implications for Illness and Health (ed. Claridge, G.). Oxford University Press: Oxford.Google Scholar
Jenner, J.A., van de Willige, G. & Wiersma, D. (1998). Effectiveness of cognitive therapy with coping training for persistent auditory hallucinations: a retrospective study ofattenders of a psychiatric outpatient department. Acta Psychiatrica Scandinavica 98, 384389.CrossRefGoogle Scholar
Johns, L.C. & McGuire, P.K. (1999). Verbal self-monitoring and auditory hallucinations in schizophrenia [letter]. Lancet 353, 469470.CrossRefGoogle ScholarPubMed
Johns, L.C., Nazroo, J.Y., Bebbington, P. & Kuipers, E. (1998). Occurrence of hallucinations in a community sample. Schizophrenia Research 29, 23.CrossRefGoogle Scholar
Jones, C., Cormac, I., Mota, J. & Campbell, C. (2000). Cognitive behaviour therapy for schizophrenia. Cochrane Database Syst Rev 2.Google ScholarPubMed
Kendell, R.E. (1985). Schizophrenia: clinical features. In Psychiatry, Vol 1 (ed. Michels, R. and Cavenar, J.O.). Basic Books: London.Google Scholar
Kendler, K.S. & Gardner, C.O. (1998). Boundaries of major depression: an evaluation of DSM-IV criteria. American Journal of Psychiatry 155, 172177.CrossRefGoogle ScholarPubMed
Kendler, K.S. & Kidd, K.K. (1986). Recurrence risks in an oligogenic threshold model: the effect of alterations in allele frequency. Annals of Human Genetics 50, 8391.CrossRefGoogle Scholar
Kendler, K.S. & Walsh, D. (1995). Schizotypal personality disorder in parents and the risk for schizophrenia in siblings. Schizophrenia Bulletin 21, 4752.CrossRefGoogle ScholarPubMed
Kendler, K.S., McGuire, M., Gruenberg, A.M., O'Hare, A., Spellman, M. & Walsh, D. (1993). The Roscommon Family Study: III. Schizophrenia-related personality disorders in relatives. Archives of General Psychiatry 50, 781788.CrossRefGoogle ScholarPubMed
Kendler, K.S., McGuire, M., Gruenberg, A.M. & Walsh, D. (1995). Schizotypal symptoms and signs in the Roscommon Family Study. Their factor structure and familial relationship with psychotic and affective disorders. Archives of General Psychiatry 52, 296303.CrossRefGoogle ScholarPubMed
Kendler, K.S., Gallagher, T.J., Abelson, J.M. & Kessler, R.C. (1996). Lifetime prevalence, demographic risk factors, and diagnostic validity of nonaffective psychosis as assessed in a US community sample. The National Comorbidity Survey. Archives of General Psychiatry 53, 10221031.CrossRefGoogle Scholar
Kuipers, E. (1996). The management of difficult to treat patients with schizophrenia, using non-drug therapies. British Journal of Psychiatry Supplement, Dec, 4151.CrossRefGoogle Scholar
Kwapil, T.R., Miller, M.B., Zinser, M.C., Chapman, J. & Chapman, L.J. (1997). Magical ideation and social anhedonia as predictors of psychosis proneness: A partial replication. Journal of Abnormal Psychology 106, 491495.CrossRefGoogle ScholarPubMed
Launay, G. & Slade, P.D. (1981). The measurement of hallucinatory predisposition in male and female prisoners. Personality and Individual Differences 2, 221234.CrossRefGoogle Scholar
Lewis, S.W., Tarrier, N., Haddock, G., Bentall, R., Kinderman, P.& Kingdon, D. (2000). A multicentre, randomised controlled trial of cognitive-behaviour therapy in first- and second-episode schizophrenia: The SoCRATES trial. Schizophrenia Research 36, 329.Google Scholar
Liddle, P.F. (1987). The symptoms of chronic schizophrenia. A reexamination of the positive-negative dichotomy. British Journal of Psychiatry 151, 145151.CrossRefGoogle ScholarPubMed
Maher, B.A. (1974). Delusional thinking and perceptual disorder. Journal of Individual Psychology 30, 98113.Google ScholarPubMed
Maher, B.A. (1988). Anomalous experience and delusional thinking: the logic of explanations. In Delusional Beliefs (ed. Oltmanns, T.F. and Maher, B.A.), pp. 1533. Wiley: New York.Google Scholar
Marcelis, M., Navarro-Mateu, F., Murray, R., Selten, J.P. & van Os, J. (1998). Urbanization and psychosis: a study of 1942-1978 birth cohorts in The Netherlands. Psychological Medicine 28, 871879.CrossRefGoogle ScholarPubMed
McKellar, P. (1968). Experience and Behaviour. Penguin Press: Harmondsworth.Google Scholar
Peralta, V., de Leon, J. & Cuesta, M.J. (1992). Are there more than two syndromes in schizophrenia? A critique of the positive-negative dichotomy. British Journal of Psychiatry 161, 335343.CrossRefGoogle ScholarPubMed
Peters, E., Day, S., McKenna, J. & Orbach, G. (1999a). Delusional ideation in religious and psychotic populations. British Journal of Clinical Psychology 38, 8396.CrossRefGoogle ScholarPubMed
Peters, E.R., Joseph, S.A. & Garety, P.A. (1999b). Measurement of delusional ideation in the normal population: introducing the PDI (Peters et al. Delusions Inventory). Schizophrenia Bulletin 25, 553576.CrossRefGoogle Scholar
Posey, T.B. & Losch, M.E. (1983). Auditory hallucinations of hearing voices in 375 normal subjects. Imagination, Cognition and Personality 3, 99113.CrossRefGoogle Scholar
Poulton, R., Caspi, A., Moffitt, T.E., Cannon, M., Murray, R. & Harrington, H. (2000). Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study. Archives of General Psychiatry 57, 10531058.CrossRefGoogle ScholarPubMed
Raine, A., Reynolds, C., Lencz, T., Scerbo, A., Triphon, N. &Kim, D. (1994). Cognitive-perceptual, interpersonal, and disorganized features of schizotypal personality. Schizophrenia Bulletin 20, 191201.CrossRefGoogle ScholarPubMed
Romme, M.A., Honig, A., Noorthoora, E.O. & Escher, A.D. (1992). Coping with hearing voices: an emancipatory approach. British Journal of Psychiatry 161, 99103.CrossRefGoogle ScholarPubMed
Rose, G. & Barker, D.J.P. (1978). What is a case? Dichotomy or continuum. British Medical Journal ii, 873874.CrossRefGoogle Scholar
Rust, J. (1988). The Rust Inventory of Schizotypal Cognitions (RISC). Schizophrenia Bulletin 14, 317322.CrossRefGoogle ScholarPubMed
Sidgewick, H., Johnson, A., Myers, F.W.H. et al. . (1894). Report of the census of hallucinations. Proceedings of the Society for Psychical Research 26, 259394.Google Scholar
Strauss, J.S. (1969). Hallucinations and delusions as points on continua function. Rating scale evidence. Archives of General Psychiatry 21, 581586.CrossRefGoogle ScholarPubMed
Tarrier, N., Yusupoff, L., Kinney, C., McCarthy, E., Gledhill, A., Haddock, G. & Morris, J. (1998). Randomised controlled trial of intensive cognitive behaviour therapy for patients with chronic schizophrenia. British Medical Journal 317, 303307.CrossRefGoogle ScholarPubMed
Tien, A.Y. (1991). Distributions of hallucinations in the population. Social Psychiatry and Psychiatric Epidemiology 26, 287292.CrossRefGoogle ScholarPubMed
Tien, A.Y., Costa, P.T. & Eaton, W.W. (1992). Covariance of personality, neurocognition, and schizophrenia spectrum traits in the community. Schizophrenia Research 7, 149158.CrossRefGoogle ScholarPubMed
van Os, J., Takei, N., Verdoux, H. & Delespaul, P. (1997). Early detection of schizophrenia [letter]. British Journal of Psychiatry 170,25.CrossRefGoogle ScholarPubMed
van Os, J., Jones, P., Sham, P., Bebbington, P. & Murray, R.M. (1998). Risk factors for onset and persistence of psychosis. Social Psychiatry and Psychiatric Epidemiology 33, 596605.CrossRefGoogle ScholarPubMed
van Os, J., Verdoux, H., Bijl, R. & Ravelli, A. (1999). Psychosis as a continuum of variation in dimensions of psychopathology. In Search for the Causes of Schizophrenia, Vol IV (ed. Häfner, H. and Gattaz, W.F.), pp 5980. Springer: Berlin.CrossRefGoogle Scholar
van Os, J., Hanssen, M., Bijl, R.V. & Ravelli, A. (2000). Strauss (1969) revisited: a psychosis continuum in the general population? Schizophrenia Research 45, 1120.CrossRefGoogle ScholarPubMed
van Os, J., Hanssen, M., Bijl, R.V. & Vollebergh, W. (2001). Prevalence of psychotic disorder and community level of psychotic symptoms: an urban-rural comparison. Archives of General Psychiatry 58, 663668.CrossRefGoogle ScholarPubMed
Venables, P.H. & Bailes, K. (1994). The structure of schizotypy, its relation to subdiagnoses of schizophrenia and to sex and age. British Journal of Clinical Psychology 33, 277294.CrossRefGoogle ScholarPubMed
Verdoux, H., Maurice-Tison, S., Gay, B., van Os, J., Salamon, R. & Bourgeois, M.L. (1998a). A survey of delusional ideation in primary-care patients. Psychological Medicine 28, 127134.CrossRefGoogle ScholarPubMed
Verdoux, H., van Os, J., Maurice-Tison, S., Gay, B., Salamon, R. & Bourgeois, M. (1998b). Is early adulthood a critical developmental stage for psychosis proneness? A survey of delusional ideation in normal subjects. Schizophrenia Research 29, 247254.CrossRefGoogle ScholarPubMed
Vollema, M. (1999). Schizotypy: toward the Psychological Heart of Schizophrenia. Shaker Publishing: Groningen.Google Scholar
Vollema, M.G. & Hoijtink, H. (2000). The multidimensionality of selfreportschizotypy in a psychiatric population: an analysis using multidimensional Rasch models. Schizophrenia Bulletin 26, 565575.CrossRefGoogle Scholar
Vollema, M.G. & van den Bosch, R.J. (1995). The multidimensionality of schizotypy. Schizophrenia Bulletin 21, 1931.CrossRefGoogle ScholarPubMed
Weich, S. (1997). Prevention of the common mental disorders: a public health perspective. Psychological Medicine 27, 757764.CrossRefGoogle ScholarPubMed
West, D.J. (1948). A mass-observation questionnaire on hallucinations. Journal of the Society for Psychical Research 34, 187196.Google Scholar
Whittington, J.E. & Huppert, F.A. (1996). Changes in the prevalence of psychiatric disorder in a community are related to changes in the mean level of psychiatric symptoms. Psychological Medicine 26, 12531260.CrossRefGoogle Scholar
World Health Organisation (1992). The ICD-10 Classification of Mental and Behavioural Disorders. World Health Organisation: Geneva.Google Scholar
Wykes, T., Parr, A.M. & Landau, S. (1999). Group treatment of auditory hallucinations. Exploratory study of effectiveness. British Journal of Psychiatry 175, 180185.CrossRefGoogle ScholarPubMed
Young, H.F., Bentall, R.P., Slade, P.D. & Dewey, M.E. (1986). Disposition towards hallucination, gender and EPQ scores: A brief report. Personality and Individual Differences 7, 247249.CrossRefGoogle Scholar