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Emotion-Based Decision Making in schizophrenia: evidence from the Iowa Gambling Task

Published online by Cambridge University Press:  11 April 2011

Marcella Bellani ,
Luisa Tomelleri  and
Paolo Brambilla
Marcella Bellani*
Affiliation:
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona (Italy) Inter-University Centre of Behavioural Neurosciences (ICBN), University of Verona and University of Udine (Italy) CERT-BD, Department of Psychiatry, University of North Carolina (USA)
Luisa Tomelleri
Affiliation:
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona (Italy) Inter-University Centre of Behavioural Neurosciences (ICBN), University of Verona and University of Udine (Italy)
Paolo Brambilla
Affiliation:
Inter-University Centre of Behavioural Neurosciences (ICBN), University of Verona and University of Udine (Italy) Section of Psychiatry, Department of Pathology and Experimental & Clinical Medicine, University of Udine (Italy) Scientific Institute ‘E. Medea’, Udine (Italy) CERT-BD, Department of Psychiatry, University of North Carolina (USA)
*
Dr. M. Bellani, Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona (Italy). Fax: +39-045-585.871 E-mail: [email protected]
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Extract

The decision making can be defined as the mental process in which a “choice is made after reflecting on the consequences of that choice” (Bechara & Van Der Linden, 2005; Bechara et al., 1997). It is a complex process that involves cognitive as well as emotion-based functions. In fact human beings make fast adaptive decisions in daily life, and that is based on the skill to relate emotion to contextual stimuli in order to anticipate outcomes through activation of emotional states (Bechara et al., 2005). In this regard, the ventromedial prefrontal cortex (VMPFC) has been widely recognized to play a key role in the emotional decision making process. The VMPFC includes the medial part of the orbitofrontal cortex (OFC), the more ventral sectors of the medial prefrontal cortex and the anterior cingulate cortex (Bechara et al., 1997). In particular the OFC, within the VMPFC, is part of a neural system underpinning decision-making and reward-related behaviours which are thought to be linked to social conduct (Rolls, 2000).

Keywords

emotional decision-makingorbitofrontal cortexschizophrenia
Type
Neurobiology of Psychosis. Clinical and Psychosocial Implications
Information
Epidemiology and Psychiatric Sciences , Volume 18 , Issue 2 , June 2009 , pp. 104 - 106
Copyright
Copyright © Cambridge University Press 2009

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