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Eating disorders and obesity: two sides of the same coin?

Published online by Cambridge University Press:  11 April 2011

Jemma Day ,
Andrew Ternouth  and
David A. Collier
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Abstract

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The eating disorders anorexia and bulimia nervosa have traditionally been regarded as entirely separate from obesity. Eating disorders have been regarded as Western culture-bound syndromes, arising in societies with excessive emphasis on weight, shape and appearance, and best treated by psychological therapies, in particular cognitive behavioural therapy or familybased interventions. In contrast, obesity has been considered a medical illness with metabolic and genetic origins, and thought to be best treated by mainstream medicine, involving dietary, drug or surgical treatment. We believe that this polarisation is fundamentally flawed, and research and treatment of both types of disorder would be better served by greater appreciation of the psychosocial components of obesity and the biological and genetic components of eating disorders. There are similarities in phenotype (such as excessive attempts at weight control, binge eating behaviours) and in risk factors (such as low self-esteem, external locus of control, childhood abuse and neglect, dieting, media exposure, body image dissatisfaction, weight-related teasing and shared susceptibility genes). One example of shared genetic risk is the brain-derived neurotrophic factor (BNDF) gene, in which the valine allele of the Va166Met amino acid polymorphism predisposes to obesity, whereas the methionine allele predisposes to eating disorders. Thus the evidence suggests that these disorders will have both shared and distinct susceptibility factors; some will predispose to both types of disorder, some will push in opposite directions, and some will separate them.

Type
Editorials
Information
Epidemiology and Psychiatric Sciences , Volume 18 , Issue 2 , June 2009 , pp. 96 - 100
Copyright
Copyright © Cambridge University Press 2009

References

American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorders, 4th ed. APA: Washington.Google Scholar
Bau, A.M., Ernert, A., Schenk, L., Wiegand, S., Martus, P., Gruters, A. & Krude, H. (2009). Is there a further acceleration in the age at onset of menarche? A cross-sectional study in 1840 school children focusing on age and bodyweight at the onset of menarche. European Journal of Endocrinology 160, 107–113.CrossRefGoogle Scholar
Brytek, A. (2006). Coping strategies, self-esteem and anger in French patients with anorexia nervosa. Psychology & Health 21, 25–25.Google Scholar
Bulik, C.M., Sullivan, P.F. & Kendler, K.S. (1998). Heritability of binge-eating and broadly defined bulimia nervosa. Biological Psychiatry 44, 1210–1218.CrossRefGoogle ScholarPubMed
Bulik, C.M., Sullivan, P.F., Wade, T.D. & Kendler, K.S. (2000). Twin studies of eating disorders: a review. International Journal of Eating Disorders 27, 1–20.3.0.CO;2-Q>CrossRefGoogle ScholarPubMed
Davis, M., Young, L., Davis, S.P. & Moll, G. (2008). Parental depression, family functioning and obesity among African American children. Journal of Cultural Diversity 15, 61–65.Google ScholarPubMed
Fairburn, C.G., Cooper, Z., Doll, H.A. & Welch, S.L. (1999). Risk factors for anorexia nervosa: three integrated case-control comparisons. Archives of General Psychiatry 56, 468–476.CrossRefGoogle ScholarPubMed
Fernandez-Aranda, F., Pinheiro, A.P., Thornton, L.M., Berrettini, W.H., Crow, S., Fichter, M.M., Halmi, K.A., Kaplan, A.S., Keel, P., Mitchell, J., Rotondo, A., Strober, M., Woodside, D.B., Kaye, W.H. & Bulik, C.M. (2008). Impulse control disorders in women with eating disorders. Psychiatry Research 157, 147–157.CrossRefGoogle ScholarPubMed
Fouts, G. & Vaughan, K. (2002). Locus of control, television viewing, and eating disorder symptomatology in young females. Journal of Adolescence 25, 307–311.CrossRefGoogle ScholarPubMed
Frayling, T.M., Timpson, N.J., Weedon, M.N., Zeggini, E., Freathy, R.M., Lindgren, C.M., Perry, J.R., Elliott, K.S., Lango, H., Rayner, N.W., Shields, B., Harries, L.W., Barrett, J.C., Ellard, S., Groves, C.J., Knight, B., Patch, A.M., Ness, A.R., Ebrahim, S., Lawlor, D.A., Ring, S.M., Ben-Shlomo, Y., Jarvelin, M.R., Sovio, U., Bennett, A.J., Melzer, D., Ferrucci, L., Loos, R.J., Barroso, I., Wareham, N.J., Karpe, F., Owen, K.R., Cardon, L.R., Walker, M., Hitman, G.A., Palmer, C.N., Doney, A.S., Morris, A.D., Smith, G.D., Hattersley, A.T. & McCarthy, M.I. (2007). A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316(5826), 889–894.CrossRefGoogle ScholarPubMed
Gibson, L.Y., Byrne, S.M., Blair, E., Davis, E.A., Jacoby, P. & Zubrick, S.R. (2008). Clustering of psychosocial symptoms in overweight children. Australian and New Zealand Journal of Psychiatry 42, 118–125.CrossRefGoogle ScholarPubMed
Gilbert, R., Widom, C.S., Browne, K., Fergusson, D., Webb, E. & Janson, S. (2009. Burden and consequences of child maltreatment in high-income countries. Lancet 373(9657), 68–81.CrossRefGoogle Scholar
Goudie, A.J., Cole, J.C., Sumnall, H. & Field, M. (2008). Impulsivity related to “obesity” and alcohol use in young women. Appetite 51, 761–761.CrossRefGoogle Scholar
Grace, P.S., Jacobson, R.S. & Fullager, C.J. (1985). A pilot comparison of purging and non-purging bulimics. Journal of Clinical Psychology 41, 173–180.3.0.CO;2-N>CrossRefGoogle ScholarPubMed
Gunstad, J., Schofield, P., Paul, R.H., Spitznagel, M.B., Cohen, R.A., Williams, L.M., Kohn, M. & Gordon, E. (2006a). BDNF Va166Met polymorphism is associated with body mass index in healthy adults. Neuropsychobiology 53, 153–156.CrossRefGoogle Scholar
Gunstad, J., Paul, R.H., Spitznagel, M.B., Cohen, R.A., Williams, L.M., Kohn, M. & Gordon, E. (2006b). Exposure to early life trauma is associated with adult obesity. Psychiatry Research 30, 142, 31–37.CrossRefGoogle Scholar
Haines, J. & Neumark-Sztainer, D. (2006). Prevention of obesity and eating disorders: a consideration of shared risk factors. Health Education Research, 21, 770–82.CrossRefGoogle ScholarPubMed
Hallstrom, T. & Noppa, H. (1981). Obesity in women in relation to mental illness, social factors and personality traits. Journal of Psychosomatic Research 25, 75–82.CrossRefGoogle ScholarPubMed
Harding, T.P. & Lachenmeyer, J.R. (1986). Family interaction patterns and locus of control as predictors of the presence and severity of anorexia nervosa. Journal of Clinical Psychology 42, 440–448.3.0.CO;2-H>CrossRefGoogle ScholarPubMed
Hay, P.J., Mond, J., Buttner, P. & Darby, A. (2008). Eating disorder behaviors are increasing: findings from two sequential community surveys in South Australia. Plos One 3, e1541.CrossRefGoogle ScholarPubMed
Hoek, H.W., van Hoeken, D: Review of the prevalence and incidence of eating disorders. International Journal of Eating Disorders 34, 383–396.CrossRefGoogle Scholar
Hudson, J.I., Hiripi, E., Pope, H.G. & Kessler, R.C. (2007: The prevalence and correlates of eating disorders in the national comorbidity survey replication. Biological Psychiatry 61, 348–358.CrossRefGoogle ScholarPubMed
Jacobi, C., Hayward, C., de Zwaan, M., Kraemer, H.C. & Agras, W.S. (2004). Coming to terms with risk factors for eating disorders: Application of risk terminology and suggestions for a general taxonomy. Psychological Bulletin 130, 19–65.CrossRefGoogle ScholarPubMed
Johnson, J.G., Cohen, P., Kasen, S. & Brook, J.S. (2002). Childhood adversities associated with risk for eating disorders or weight problems during adolescence or early adulthood. American Journal of Psychiatry 159, 394–400.CrossRefGoogle ScholarPubMed
Jordan, J., Joyce, P.R., Carter, F.A., Horn, J., McIntosh, V.V.W., Luty, S.E., McKenzie, J.M., Frampton, C.M.A., Mulder, R.T. & Bulik, C.M. (2008). Specific and nonspecific Comorbidity in anorexia nervosa. International Journal of Eating Disorders 41, 47–56.CrossRefGoogle ScholarPubMed
Lee, W.W. (2007). An overview of pediatric obesity. Pediatric Diabetes 8, Suppl 9, 76–87.CrossRefGoogle ScholarPubMed
Lissau, I. & Sørensen, T.I. (1994). Parental neglect during childhood and increased risk of obesity in young adulthood. Lancet 343(8893), 324–327.CrossRefGoogle ScholarPubMed
Loos, R.J., Lindgren, C.M., Li, S., Wheeler, E., Zhao, J.H., Prokopenko, I., Inouye, M., Freathy, R.M., Attwood, A.P., Beckmann, J.S., Berndt, S.I., Prostate, Lung, Colorectal, , and Ovarian, (PLCO) Cancer Screening Trial, Jacobs, K.B., Chanock, S.J., Hayes, R.B., Bergmann, S., Bennett, A.J., Bingham, S.A., Bochud, M., Brown, M., Cauchi, S., Connell, J.M., Cooper, C., Smith, G.D., Day, I., Dina, C., De, S., Dermitzakis, E.T., Doney, A.S., Elliott, K.S., Elliott, P., Evans, D.M., Sadaf, Farooqi I., Froguel, P., Ghori, J., Groves, C.J., Gwilliam, R., Hadley, D., Hall, A.S., Hattersley, A.T., Hebebrand, J., Heid, I.M.; Kora, Lamina C., Gieger, C., Illig, T., Meitinger, T., Wichmann, H.E., Herrera, B., Hinney, A., Hunt, S.E., Jarvelin, M.R., Johnson, T., Jolley, J.D., Karpe, F., Keniry, A., Khaw, K.T., Luben, R.N., Mangino, M., Marchini, J., McArdle, W.L., McGinnis, R., Meyre, D., Munroe, P.B., Morris, A.D., Ness, A.R., Neville, M.J., Nica, A.C., Ong, K.K., O'Rahilly, S., Owen, K.R., Palmer, C.N., Papadakis, K., Potter, S., Pouta, A., Qi, L., Nurses’ Health Study, Randall, J.C., Rayner, N.W., Ring, S.M., Sandhu, M.S., Scherag, A., Sims, M.A., Song, K., Soranzo, N., Speliotes, E.K., Diabetes Genetics Initiative, Syddall, H.E., Teichmann, S.A., Timpson, N.J., Tobias, J.H., Uda, M., SardiNIA Study, Vogel, C.I., Wallace, C., Waterworth, D.M., Weedon, M.N., Wellcome Trust Case Control Consortium, Willer, C.J., Fusion, Wraight, Yuan, X., Zeggini, E., Hirschhorn, J.N., Strachan, D.P., Ouwehand, W.H., Caulfield, M.J., Samani, N.J., Frayling, T.M., Vollenweider, P., Waeber, G., Mooser, V., Deloukas, P., McCarthy, M.I., Wareham, N.J., Barroso, I., Jacobs, K.B., Chanock, S.J., Hayes, R.B., Lamina, C., Gieger, C., Illig, T., Meitinger, T., Wichmann, H.E., Kraft, P., Hankinson, S.E., Hunter, D.J., Hu, F.B., Lyon, H.N., Voight, B.F., Ridderstrale, M., Groop, L., Scheet, P., Sanna, S., Abecasis, G.R., Albai, G., Nagaraja, R., Schlessinger, D., Jackson, A.U., Tuomilehto, J., Collins, F.S., Boehnke, M. & Mohlke, K.L.(2008). Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nature Genetics 40, 768–775.CrossRefGoogle ScholarPubMed
Mangweth-Matzek, B., Rupp, C.I., Hausmann, A., Kemmler, G. & Biebl, W. (2007). Menarche, puberty, and first sexual activities in eating- disordered patients as compared with a psychiatric and a nonpsychiatric control group. International Journal of Eating Disorders 40, 705–710.CrossRefGoogle Scholar
Moyer, D.M., Di, Pietro L., Berkowitz, R.I. & Stunkard, A.J. (1997). Childhood sexual abuse and precursors of binge eating in an adolescent female population. International Journal of Eating Disorders 21, 23–30.Google Scholar
Nederkoorn, C., Smulders, F.T.Y., Havermans, R.C., Roefs, A. & Jansen, A. (2006). Impulsivity in obese women. Appetite 47, 253–256.CrossRefGoogle ScholarPubMed
Nevonen, L. & Norring, C. (2004). Socio-economic variables and eating disorders: a comparison between patients and normal controls. Eating and Weight Disorders 9, 279–284.CrossRefGoogle ScholarPubMed
O’Dea, J.A. (2008). Gender, ethnicity, culture and social class influences on childhood obesity among Australian schoolchildren: implications for treatment, prevention and community education. Health and Social Care in the Community 16, 282–290.CrossRefGoogle ScholarPubMed
Pawlowska, B. & Masiak, M. (2007). Comparison of socio-demographic data of female patients with purging and restricting types of anorexia nervosa hospitalised at the Psychiatry Department of the Medical University of Lublin in the years 1993–2003). Psychiatria Polska 41, 350–364.Google ScholarPubMed
Pine, D.S., Goldstein, R.B., Wolk, S. & Weissman, M.M. (2001). The association between childhood depression and adulthood body mass index. Pediatrics 107, 1049–1056.CrossRefGoogle ScholarPubMed
Pinhas-Hamiel, O., Modan-Moses, D., Herman-Raz, M. & Reichman, B. (2009). Obesity in girls and penetrative sexual abuse in childhood. Acta Paediatrica 98, 144–147.CrossRefGoogle ScholarPubMed
Power, C., Manor, O. & Matthews, S. (2003). Child to adult socioeconomic conditions and obesity in a national cohort. International Journal of Obesity and Related Metabolic Disorders 27, 1081–1086.CrossRefGoogle Scholar
Preti, A., Incani, E., Camboni, M.V., Petretto, D.R. & Masala, C. (2006). Sexual abuse and eating disorder symptoms: the mediator role of bodily dissatisfaction. Comprehensive Psychiatry 47, 475–481.CrossRefGoogle ScholarPubMed
Ribasés, M., Gratacòs, M., Fernández-Aranda, F., Bellodi, L., Boni, C., Anderluh, M., Cavallini, M.C., Cellini, E., Di, Bella D., Erzegovesi, S., Foulon, C., Gabrovsek, M., Gorwood, P., Hebebrand, J., Hinney, A., Holliday, J., Hu, X., Karwautz, A., Kipman, A., Komel, R., Nacmias, B., Remschmidt, H., Ricca, V., Sorbi, S., Wagner, G., Treasure, J., Collier, D.A. & Estivill, X. (2004). Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations. Human Molecular Genetics 13, 1205–1212.CrossRefGoogle ScholarPubMed
Roehrig, M., Masheb, R.M., White, M.A. & Grilo, C.M. (2009). Dieting frequency in obese patients with binge eating disorder: Behavioral and metabolic correlates. Obesity 17, 481–486.CrossRefGoogle ScholarPubMed
Rohde, P., Ichikawa, L., Simon, G.E., Ludman, E.J., Linde, J.A., Jeffery, R.W. & Operskalski, B.H. (2008). Associations of child sexual and physical abuse with obesity and depression in middle-aged women. Child Abuse and Neglect 32, 878–887.CrossRefGoogle ScholarPubMed
Sanci, L., Coffey, C., Epi, G.D., Olsson, C., Reid, S., Carlin, J.B. & Patton, G. (2008). Childhood sexual abuse and eating disorders in females. Archives of Pediatrics & Adolescent Medicine 162, 261–267.CrossRefGoogle ScholarPubMed
Shin, N.Y. & Shin, M.S. (2008). Body dissatisfaction, self-esteem, and depression in obese Korean children. Journal of Pediatrics 152, 502–506.CrossRefGoogle ScholarPubMed
Shisslak, C.M., Pazda, S.L. & Crago, M. (1990). Body weight and bulimia as discriminators of psychological characteristics among anorexic, bulimic, and obese women. Journal of Abnormal Psychology 99, 380–384.CrossRefGoogle ScholarPubMed
StClair, D. (2009). Copy number variation and schizophrenia. Schizophrenia Bulletin 35, 9–12.CrossRefGoogle Scholar
Stunkard, A.J., Foch, T.T. & Hrubec, Z. (1986). A twin study of human obesity. Journal of American Medical Association 256(1), 51–54.CrossRefGoogle ScholarPubMed
Taylor, S.J., Viner, R., Booy, R., Head, J., Tate, H., Brentnall, S.L., Haines, M., Bhui, K., Hillier, S. & Stansfeld, S. (2005). Ethnicity, socioeconomic status, overweight and underweight in East London adolescents. Ethnicity and Health 10, 113–128.CrossRefGoogle ScholarPubMed
Terres, N.G., Pinheiro, R.T., Horta, B.L., Pinheiro, K.A.T. & Horta, L.L. (2006). Prevalence and factors associated to overweight and obesity in adolescents. Revista de Saude Publica 40, 627–633.CrossRefGoogle ScholarPubMed
Thorleifsson, G., Walters, G.B., Gudbjartsson, D.F., Steinthorsdottir, V., Sulem, P., Helgadottir, A., Styrkarsdottir, U., Gretarsdottir, S., Thorlacius, S., Jonsdottir, I., Jonsdottir, T., Olafsdottir, E.J., Olafsdottir, G.H., Jonsson, T., Jonsson, F., Borch-Johnsen, K., Hansen, T., Andersen, G., Jorgensen, T., Lauritzen, T., Aben, K.K., Verbeek, A.L., Roeleveld, N., Kampman, E., Yanek, L.R., Becker, L.C., Tryggvadottir, L., Rafnar, T., Becker, D.M., Gulcher, J., Kiemeney, L.A., Pedersen, O., Kong, A., Thorsteinsdottir, U. & Stefansson, K. (2009). Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nature Genetics 41, 18–24.CrossRefGoogle ScholarPubMed
Troisi, A., Di, Lorenzo G., Alcini, S., Nanni, R.C., Di, Pasquale C. & Siracusano, A. (2006). Body dissatisfaction in women with eating disorders: Relationship to early separation anxiety and insecure attachment. Psychosomatic Medicine 68, 449–453.CrossRefGoogle ScholarPubMed
Willer, C.J., Speliotes, E.K., Loos, R.J., Li, S., Lindgren, C.M., Heid, I.M., Berndt, S.I., Elliott, A.L., Jackson, A.U., Lamina, C., Lettre, G., Lim, N., Lyon, H.N., McCarroll, S.A., Papadakis, K., Qi, L., Randall, J.C., Roccasecca, R.M., Sanna, S., Scheet, P., Weedon, M.N., Wheeler, E., Zhao, J.H., Jacobs, L.C., Prokopenko, I., Soranzo, N., Tanaka, T., Timpson, N.J., Almgren, P., Bennett, A., Bergman, R.N., Bingham, S.A., Bonnycastle, L.L., Brown, M., Burtt, N.P., Chines, P., Coin, L., Collins, F.S., Connell, J.M., Cooper, C., Smith, G.D., Dennison, E.M., Deodhar, P., Elliott, P., Erdos, M.R., Estrada, K., Evans, D.M., Gianniny, L., Gieger, C., Gillson, C.J., Guiducci, C., Hackett, R., Hadley, D., Hall, A.S., Havulinna, A.S., Hebebrand, J., Hofman, A., Isomaa, B., Jacobs, K.B., Johnson, T., Jousilahti, P., Jovanovic, Z., Khaw, K.T., Kraft, P., Kuokkanen, M., Kuusisto, J., Laitinen, J., Lakatta, E.G., Luan, J., Luben, R.N., Mangino, M., McArdle, W.L., Meitinger, T., Mulas, A., Munroe, P.B., Narisu, N., Ness, A.R., Northstone, K., O'Rahilly, S., Purmann, C., Rees, M.G., Ridderstråle, M., Ring, S.M., Rivadeneira, F., Ruokonen, A., Sandhu, M.S., Saramies, J., Scott, L.J., Scuteri, A., Silander, K., Sims, M.A., Song, K., Stephens, J., Stevens, S., Stringham, H.M., Tung, Y.C., Valle, T.T., Van Duijn, C.M., Vimaleswaran, K.S., Vollenweider, P., Waeber, G., Wallace, C., Watanabe, R.M., Waterworth, D.M., Watkins, N., Wellcome Trust Case Control Consortium, Witteman, J.C., Zeggini, E., Zhai, G., Zillikens, M.C., Altshuler, D., Caulfield, M.J., Chanock, S.J., Farooqi, I.S., Ferrucci, L., Guralnik, J.M., Hattersley, A.T., Hu, F.B., Jarvelin, M.R., Laakso, M., Mooser, V., Ong, K.K., Ouwehand, W.H., Salomaa, V., Samani, N.J., Spector, T.D., Tuomi, T., Tuomilehto, J., Uda, M., Uitterlinden, A.G., Wareham, N.J., Deloukas, P., Frayling, T.M., Groop, L.C., Hayes, R.B., Hunter, D.J., Mohlke, K.L., Peltonen, L., Schlessinger, D., Strachan, D.P., Wichmann, H.E., McCarthy, M.I., Boehnke, M., Barroso, I., Abecasis, G.R., Hirschhorn, J.N. & Genetic Investigation of Anthropometric Traits Consortium (2009). Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genetics 41, 25–34.Google ScholarPubMed
World Health Organization (2000). Obesity: Preventing and Managing the Global Epidemic. WHO Technical Report Series 894. WHO: Geneva.Google Scholar
Wonderlich, S.A., Connolly, K.M. & Stice, E. (2004). Impulsivity as a risk factor for eating disorder behavior: Assessment implications with adolescents. International Journal of Eating Disorders 36, 172–182.CrossRefGoogle ScholarPubMed
Yeomans, M.R., Leitch, M. & Mobini, S. (2008). Impulsivity is associated with the disinhibition but not restraint factor from the Three Factor Eating Questionnaire. Appetite 50, 469–476CrossRefGoogle Scholar