Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-05T05:02:49.124Z Has data issue: false hasContentIssue false
  • English
  • Français

Developmental biomarkers in schizophrenia and other psychiatric disorders: common origins, different trajectories?

Published online by Cambridge University Press:  11 October 2011

Matcheri S. Keshavan ,
Vaibhav Diwadkar  and
David R. Rosenberg
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Editorials
Information
Epidemiology and Psychiatric Sciences , Volume 14 , Issue 4 , December 2005 , pp. 188 - 193
Copyright
Copyright © Cambridge University Press 2005

References

REFERENCES

Adler, C.M. & Strakowski, S.M. (2003) Boundaries of schizophrenia. Psycliiatric Clinics of North America 26, 1–23.CrossRefGoogle ScholarPubMed
Altshuler, L.L., Bartzokis, G., Grieder, T., Curran, J., Jimenez, T., Leight, K., Wilkins, J., Gerner, R. & Mintz, J. (2000). An MRI study of temporal lobe structures in men with bipolar disorder or schizophrenia. Biological Psychiatry 48, 147–162.CrossRefGoogle ScholarPubMed
Andreasen, N.C., Rezai, K., Alliger, R., Swayze, V.W. 2nd, Flaum, M., Kirchner, P., Cohen, G. & O'Leary, D.S. (1992). Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Assessment with xenon 133 single-photon emission computed tomography and the Tower of London. Archives of General Psychiatry 49, 943–958.CrossRefGoogle ScholarPubMed
Badner, J.A. & Gershon, E.S. (2002). Meta-analysis of whole-genome scans of bipolar disorder and schizophrenia. Molecular Psychiatry 7, 405–411.CrossRefGoogle Scholar
Bartha, R., Stein, M.B., Williamson, P.C, Drost, D.J., Neufeld, R.W., Carr, T.J., Canaran, G., Densmore, M., Anderson, G. & Siddiqui, A.R. (1998). A short echo 1H spectroscopy and volumetric MRI study of the corpus striatum in patients with obsessive compulsive disorder and comparison subjects. American Journal of Psychiatry 155, 1584–1591.CrossRefGoogle Scholar
Bellak, L., Kay, S.R. & Opler, L.A. (1987). Attention deficit disorder psychosis as a diagnostic category. Psychiatric Developments 5, 239–263.Google ScholarPubMed
Benjamin, J., Li, L., Patterson, C, Greenberg, B.D., Murphy, D.L. & Hamer, D.H. (1996). Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking. Nature Genetics 12, 81–84.CrossRefGoogle ScholarPubMed
Berrettini, W. (2003). Evidence for shared susceptibility in bipolar dis-order and schizophrenia. American Journal of Medical Genetics Part C: Seminars in Medical Genetics 123(1), 59–64.CrossRefGoogle Scholar
Brambilla, P., Harenski, K., Nicoletti, M.A., Mallinger, A.G., Frank, E., Kupfer, D.J., Keshavan, M.S. & Soares, J.C. (2001). Anatomical MRI study of basal ganglia in bipolar disorder patients. Psychiatry Research 106 65–80.CrossRefGoogle ScholarPubMed
Buka, S. & Fan, A. (1999). Association of prenatal and perinatal complications with subsequent bipolar disorder and schizophrenia. Schizophrenia Research 39, 113–119.CrossRefGoogle Scholar
Caplan, R., Guthrie, D., Tang, B., Nuechterlein, K.H. & Asarnow, R.E. (2002). Thought disorder in attention-deficit hyperactivity disorder. International Review Neurobiology 49, 269–284.CrossRefGoogle Scholar
Castellanos, F.X., Lee, P.P., Sharp, W., Jeffries, N.O., Greenstein, D.K., Clasen, L.S., Blumenthal, J.D., James, R.S., Ebens, C.L., Walter, J.M., Zijdenbos, A., Evans, A.C., Giedd, J.N. & Rapoport, J.L. (2002). Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. Journal of the American Medical Association 288, 1740–1748.CrossRefGoogle ScholarPubMed
Chang, K.D., Steiner, H. & Ketter, T.A. (2000). Psychiatric phenomenology of child and adolescent bipolar offspring. Journal of the American Academy of Child and Adolescent Psychiatry 39, 453–460.CrossRefGoogle ScholarPubMed
Cook, E.H., Sterin, M.A., Krasowski, M.D., Cox, N.J., Olkon, D.M., Kieffer, J.E. & Leventhal, B.L. (1995). Association of attention-deficit disorder and the dopamine transporter gene. American Journal of Human Genetics 56, 993–998.Google ScholarPubMed
Drevets, W.C. (1999). Prefrontal cortical-amygdalar metabolism in major depression. Annals of the New York Academy of Sciences 877, 614–637.CrossRefGoogle ScholarPubMed
Drevets, W.C. (2000). Neuroimaging studies of mood disorders. Biological Psychiatry 48, 813–829."CrossRefGoogle ScholarPubMed
Durston, S., Hulshoff Pol, H.E., Casey, B.J., Giedd, J.N., Buitelaar, J.K. & van Engeland, H. (2001). Anatomical MRI of the developing human brain: What have we learned? Journal of the American Academy of Child and Adolescent Psychiatry 40, 1012–1020.CrossRefGoogle ScholarPubMed
Ebert, D., Speck, O., Konig, A., Berger, M., Hennig, J. & Hohagen, F. (1997). lH-magnetic resonance spectroscopy in obsessive-compulsive disorder: Evidence for neuronal loss in the cingulate gyrus and the right striatum. Psychiatry Research 74, 173–176.CrossRefGoogle ScholarPubMed
Ebstein, R.P., Novick, O., Umansky, R., Priel, B., Osher, Y., Blaine, D., Bennet, E.R., Nemanov, L., Katz, M. & Belmaker, R.H. (1996). Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking. Nature Genetics 12, 78–80.CrossRefGoogle ScholarPubMed
Fitzgerald, K.D., Welsh, R.C., Gehring, W.J., Abelson, J.L., Himle, J.A., Liberzon, I. & Taylor, S.F. (2005) Error-related hyperactivity of the anterior cingulate cortex in obsessive-compulsive disorder. Biological Psychiatry 57(3). 287–294.CrossRefGoogle ScholarPubMed
Frodl, T., Meisenzahl, E., Zetzsche, T., Bottlender, R., Born, C, Groll, C., Jager, M, Leinsinger, G., Hahn, K. & Moller, H.J. (2002) Enlargement of the amygdala in patients with a first episode of major depression. Biological Psychiatry 51, 708–714.CrossRefGoogle ScholarPubMed
Geller, D.A., Biederman, J., Faraone, S.V., Cradock, K., Hagermoser, L., Zaman, N., Frazier, J.A., Coffey, B.J. & Spencer, T.J. (2002). Attention-deficit/hyperactivity disorder in children and adolescents with obsessive-compulsive disorder: fact or artifact? Journal of the American Academy of Child and Adolescent Psychiatry 41, 52–58.CrossRefGoogle ScholarPubMed
Geller, B., Zimerman, B., Williams, M., Bolhofner, K. & Craney, J.L. (2001). Bipolar disorder at prospective follow-up of adults who had prepubertal major depressive disorder. American Journal of Psychiatry 158, 125–127.CrossRefGoogle ScholarPubMed
Gilbert, A.R., Moore, G.J., Keshavan, M.S., Paulson, L.A., Narula, V., Mac Master, F.P., Stewart, C.M. & Rosenberg, D.R. (2000). Decrease in thalamic volumes of pediatric patients with obsessive-compulsive disorder who are taking paroxetine. Archives of General Psychiatry 57, 449–456.CrossRefGoogle ScholarPubMed
Gilbert, A.R., Rosenberg, D.R., Harenski, K., Spencer, S., Sweeney, J.A. & Keshavan, M.S. (2001). Thalamic volumes in patients with first-episode schizophrenia. American Journal of Psychiatry 158(4), 618–624.CrossRefGoogle ScholarPubMed
Gill, M., Daly, G., Heron, S., Hawi, Z. & Fizgerald, M. (1997). Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism. Biological Psychiatry 2, 311–313.Google Scholar
Gogos, J.A., Morgan, M., Luine, V., Santha, M., Ogawa, S., Pfaff, D. & Karayiorgou, M. (1998). Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proceedings of the National Academy of Sciences of the United Stales of America US 95, 9991–9996.CrossRefGoogle ScholarPubMed
Green, E.K., Raybould, R., Macgregor, S., Gordon-Smith, K., Heron, J., Hyde, S., Grozeva, D., Hamshere, M., Williams, N., Owen, M.J., O'Donovan, M.C., Jones, L., Jones, I., Kirov, G. & Craddock, N. (2005). Operation of the schizophrenia susceptibility gene, neuregulin 1. across traditional diagnostic boundaries to increase risk for bipolar disorder. Archives of General Psychiatry 62(6). 642–648.CrossRefGoogle ScholarPubMed
Gross-Isseroff, R., Hermesh, H., Zohar, J. & Weizman, A. (2003). Neuroimaging communality between schizophrenia and obsessive compulsive disorder: a putative basis for schizo-obsessive disorder? World Journal of Biological Psychiatry 4, 129–134.CrossRefGoogle ScholarPubMed
Hariri, A.R., Drabant, E.M., Munoz, K.E., Kolachana, B.S., Mattay, V.S., Egan, M.F. & Weinberger, D.R. (2005) A susceptibility gene for affective disorders and the response of the human amygdala. Archives of General Psychiatry 62(2), 146–152.CrossRefGoogle ScholarPubMed
Harrington, R., Fudge, H., Rutter, M., Pickles, A, & Hill, J. (1990). Adult outcomes of childhood and adolescent depression: Psychiatric status. Archives of General Psychiatry 47, 465–473.CrossRefGoogle ScholarPubMed
Hesslinger, B., Thiel, T., Tebartz van Elst, L., Hennig, J. & Ebert, D. (2001). Attention-deficit disorder in adults with or without hyperactivity: Where is the difference? A study in humans using short echo (l)H-magnetic resonance spectroscopy. Neuroscience Letters 304, 117–119.CrossRefGoogle ScholarPubMed
Hill, D.E., Yeo, R.A., Campbell, R.A., Hart, B., Vigil, J. & Brooks, W. (2003). Magnetic resonance imaging correlates of attention-deficit/hyperactivity disorder in children. Neuropsvchologv 17, 496–506.CrossRefGoogle ScholarPubMed
Huttenlocher, P.R. (1979). Synaptic density in human frontal cortex. Developmental changes and effects of aging. Brain Research 163, 195.Google ScholarPubMed
Kayl, A.E., Moore, B.D. 3rd, Slopis, J.M., Jackson, E.F. & Leeds, N.E. (2000). Quantitative morphology of the corpus callosum in children with neurofibromatosis and attention-deficit hyperactivity disorder. Journal of Child Neurology 15, 90–96.CrossRefGoogle ScholarPubMed
Keshavan, M.S. (1999). Development, disease and degeneration in schizophrenia: a unitary pathophysiological model. Journal of Psychiatric Research 33(6), 513–521.CrossRefGoogle ScholarPubMed
Keshavan, M.S., Anderson, S. & Pettegrew, J.W. (1994) Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? Journal of Psychiatric Research 28, 239–265.CrossRefGoogle ScholarPubMed
Keshavan, M.S., Montrose, D.M., Pierri, J.N., Dick, E.L., Rosenberg, D., Talagala, L. & Sweeney, J.A. (1997). Magnetic resonance imaging and spectroscopy in offspring at risk for schizophrenia: preliminary studies. Progress in Neuropsvchopharmacology and Biological Psychiatry 21, 1285–1295.CrossRefGoogle ScholarPubMed
Keshavan, M.S., Rosenberg, D., Sweeney, J.A. & Pettegrew, J.W. (1998) Decreased caudate volume in neuroleptic-naive psychotic patients. American Journal of Psychiatry 155, 774–778.Google ScholarPubMed
Keshavan, M.S., Sujata, M., Mehra, A., Montrose, D.M. & Sweeney, J.A. (2002a). Psychosis proneness and ADHD in young relatives at risk for schizophrenia. Schizophrenia Research 59, 85–92.CrossRefGoogle Scholar
Keshavan, M.S., Dick, E., Mankowski, I., Harenski, K., Montrose, D.M., Diwadkar, V. & De Bellis, M. (2002b). Decreased left amygdala and hippocampal volumes in young offspring at risk for schizophrenia. Schizophrenia Research 58, 173–183.CrossRefGoogle ScholarPubMed
Kessler, R.C., Berglund, P., Dernier, O., Jin, R., Merikangas, K.R. & Walters, E.E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry Jun;62(6), 593–602. Erratum in: Archives of General Psychiatry 62(7), 768.CrossRefGoogle ScholarPubMed
Kim, E.Y. & Miklowitz, D.J. (2002). Childhood mania, attention deficit hyperactivity disorder and conduct disorder: A critical review of diagnostic dilemmas. Bipolar Disorder 4, 215–225.CrossRefGoogle ScholarPubMed
La Hoste, G.J., Swanson, J.M., Wigal, S.B., Glabe, C, Wigal, T., King, N. & Kennedy, J.L. (1996). Dopamine D4 receptor gene polymorphism is associated with attention-deficit hyperactivity disorder. Molecular Psychiatry 1, 121–124.Google ScholarPubMed
Lasky-Su, J.A., Faraone, S.V., Glatt, S.J. & Tsuang, M.T. (2005). Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders. American Journal of Medical Genetics. Part B, Neuropsxchiatric Genetics 133(1), 110–115.CrossRefGoogle Scholar
Laughlin, S.B. & Sejnowski, T.J. (2003). Communication in neuronal networks. Science 301(5641). 1870–1874.CrossRefGoogle ScholarPubMed
Lawrie, S.M., Buechel, C.Whalley, H.C., Frith, C.D., Friston, K.J. & Johnstone, E.C. (2002). Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations. Biological Psychiatry 51(12). 1008–1011.CrossRefGoogle ScholarPubMed
Ledoux, J. (2003). The emotional brain, fear, and the amygdala. Cellular and Molecular Neurobiology 23, 727–738.CrossRefGoogle ScholarPubMed
Lesch, K.P. (2004). Gene-environment interaction and the genetics of depression. Journal of Psychiatry and Neuroscience 29(3), 174–184.Google ScholarPubMed
Luxenberg, J.S., Swedo, S.E., Flament, M.F., Friedland, R.P., Rapoport, J. & Rapoport, S.I. (1988). Neuroanatomical abnormalities in obsessive-compulsive disorder detected with quantitative X-ray computed tomography. American Journal of Psychiatry 145, 1089–1093.Google ScholarPubMed
Maier, W., Hofgen, B., Zobel, A. & Rietschel, M. (2005). Genetic models of schizophrenia and bipolar disorder Overlapping inheritance or discrete genotypes? European Archives of Psvcliiatn’ and Clinical Neuroscience 255(3), 159–166.Google ScholarPubMed
Maltby, N., Tolin, D.F., Worhunsky, P., O'Keefe, T.M. & Kiehl, K.A. (2005). Dysfunctional action monitoring hyperactivates frontal-striatal circuits in obsessive-compulsive disorder: an event-related fMRI study. Neurohnage 24(2), 495–503.Google ScholarPubMed
Milberger, S., Biederman, J., Faraone, S.X., Guite, J. & Tsuang, M.T. (1997). Pregnancy, delivery, and infancy complications and attention deficit hyperactivity disorder: issues of gene-environment inter-action. Biological Psychiatry 41, 65–75.CrossRefGoogle Scholar
Moller, H.J. (2003). Bipolar disorder and schizophrenia: distinct illnesses or a continuum? Journal of Clinical Psychiatry 64, 23–27.Google ScholarPubMed
Murray, R.M., Sham, P., Van Os, J., Zanelli, J., Cannon, M. & McDonald, C. (2004). A developmental model for similarities and dissimilari-ties between schizophrenia and bipolar disorder. Schizophrenia Research 71(2-3). 405–416.CrossRefGoogle ScholarPubMed
Noga, J.T., Aylward, E., Barta, P.E. & Pearlson, G.D. (1995). Cingulate gyrus in schizophrenic patients and normal volunteers. Psychiatry Research 61, 201–208.CrossRefGoogle ScholarPubMed
Nurnberger, J.I. Jr & Foroud, T. (2000). Genetics of bipolar affective disorder. Current Psychiatry Reports 2(2), 147–157.CrossRefGoogle ScholarPubMed
O'Donovan, M.C., Wiiliams, N.M. & Owen, M.J. (2003) Recent advances in the genetics of schizophrenia. Human Molecular Genetics 12. Suppl2. R125–133.CrossRefGoogle ScholarPubMed
Penn, A.A. (2001), Early brain wiring: activity-dependent processes. Schizophrenia Bulletin 27(3), 337–347.CrossRefGoogle ScholarPubMed
Pine, D.S. (2004). Integrating research on developmental psychopathology and neuroscience in the study of adolescence: introduction to part II. Annals of the New York Academy of Sciences 1021, 61–63.CrossRefGoogle Scholar
Ramakers, G.J. (2005). Neuronal network formation in human cerebral cortex. Progress in Brain Research 147, 1–14.CrossRefGoogle ScholarPubMed
Rosenberg, D.R, Keshavan, M.S., O'Hearn, K.M., Dick, E.L., Bagwell, W.W., Seymour, A.B., Montrose, D.M., Pierri, J.N. & Birmaher, B. (1997a). Frontostriatal measurement in treatment-naive children with obsessive-compulsive disorder. Archives of General Psychiatry 54, 824–830.CrossRefGoogle ScholarPubMed
Rosenberg, D.R., Keshavan, M.S., Dick, E.L., Bagwell, W.W., MacMaster, F.P. & Birmaher, B. (1997b). Corpus callosal morphology in treatment-naive pediatric obsessive compulsive disorder. Progress in Neuropsvchopliannacologv and Biological Psychiatry 21, 1269–1283.CrossRefGoogle ScholarPubMed
Rosenberg, D.R. & Keshavan, M.S. (1998). Bennett, A.E.Research Award. Toward a neurodevelopmental model of obsessive-compulsive disorder. Biological Psychiatry 43, 623–640.CrossRefGoogle Scholar
Sawa, A. & Snyder, S. (2002). Schizophrenia: Diverse approaches to a complex disease. Science 296, 692–695.CrossRefGoogle ScholarPubMed
Shenton, M.E.Dickey, C.C., Frumin, M. & McCarley, R.W. (2001). A review of MRI findings in schizophrenia. Schizophrenia Research 15, 49(1-2). 1–52.CrossRefGoogle Scholar
Shihabuddin, L., Buchsbaum, M.S., Hazlett, E.A., Haznedar, M.M., Harvey, P.D., Newman, A., Schnur, D.B., Spiegel-Cohen, J., Wei, T., Machac, J., Knesaurek, K., Vallabhajosula, S., Biren, M.A., Ciaravolo, T.M. & Luu-Hsia, C. (1998). Dorsal striatal size, shape, and metabolic rate in never-medicated and previously medicated schizophrenics performing a verbal learning task. Archives of General Psychiatry 55, 235–243.CrossRefGoogle ScholarPubMed
Seidman, L.J., Valera, F.M. & Makris, N. (2005). Structural brain imaging of attention-deficit/hyperactivity disorder. Biological Psychiatry 27(11). 1263–1272.CrossRefGoogle Scholar
Soares, J.C. & Mann, J.J. (1997). The anatomy of mood disorders-review of structural neuroimaging studies. Biological Psychiatry 41, 86–106.CrossRefGoogle ScholarPubMed
Sowell, E.R., Toga, A.W. & Asarnow, R. (2000). Brain abnormalities observed in childhood-onset schizophrenia: A review of the structural magnetic resonance imaging literature. Mental Retardation and Developmental Disabilities Research Reviews 6, 180–185.3.0.CO;2-I>CrossRefGoogle ScholarPubMed
Sprich-Buckminster, S., Biederman, J., Milberger, S., Faraone, S.W. & Lehman, B.K. (1993). Are perinatal complications relevant to the manifestation of ADD? Issues of comorbidity and familiality. Journal of the American Academy of Child and Adolescent Psychiatry 32, 1032–1037.CrossRefGoogle Scholar
Steingard, R.J., Renshaw, P.F., Hennen, J., Lenox, M., Cintron, C.B., Young, A.D., Connor, D.F., Au, T.H. & Yurgelun-Todd, D.A. (2002). Smaller frontal lobe white matter volumes in depressed adolescents. Biological Psychiatry 52, 413–417.CrossRefGoogle ScholarPubMed
Strakowski, S.M., Del Bello, M.P., Sax, K.W., Zimmerman, M.E., Shear, P.K., Hawkins, J.M. & Larson, E.R. (1999). Brain magnetic resonance imaging of structural abnormalities in bipolar disorder. Archives of General Psychiatry 56, 254–260.CrossRefGoogle ScholarPubMed
Strakowski, S.M., Del Bello, M.P., Zimmerman, M.E., Getz, G.E., Mills, N.P., Ret, J., Shear, P. & Adler, C.M. (2002). Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder. American Journal of Psychiatry 159, 1841–1847.CrossRefGoogle ScholarPubMed
Sukhodolsky, D.G., do Rosario-Campos, M.C, Scahill, L., Katsovich, L., Pauls, D.L., Peterson, B.S., King, R.A., Lombroso, P.J., Findley, D.B. & Leckman, J.F. (2005). Adaptive, emotional, and family functioning of children with obsessive-compulsive disorder and comorbid attention deficit hyperactivity disorder. American Journal of Psychiatry 162(6), 1125–1132.CrossRefGoogle ScholarPubMed
Szeszko, P.R., MacMillan, S., McMeniman, M., Chen, S, Baribault, K., Lim, K.O., Ivey, J., Rose, M., Banerjee, S.P., Bhandari, R., Moore, G.J. & Rosenberg, D.R. (2004). Brain structural abnormalities in psychotropic drug-naive pediatric patients with obsessive-compulsive disorder. American Journal of Psychiatry 161(6), 1049–1056.CrossRefGoogle ScholarPubMed
Takahashi, T., Suzuki, M., Kawasaki, Y., Hagino, H., Yamashita, I., Nohara, S., Nakamura, K., Seto, H. & Kurachi, M. (2003). Perigenual cingulate gyrus volume in patients with schizophrenia: a magnetic resonance imaging study. Biological Psychiatry 53, 593–600.CrossRefGoogle ScholarPubMed
Thomas, K.M., Drevets, W.C., Dahl, R.E., Ryan, N.D., Birmaher, B., Eccard, C.H., Axelson, D., Whalen, P.J. & Casey, B.J. (2001). Amygdala response to fearful faces in anxious and depressed children, Archives of General Psychiatiy 58, 1057–1063.CrossRefGoogle ScholarPubMed
Verdoux, H. & Sutter, A.L. (2002). Perinatal risk factors for schizophrenia: diagnostic specificity and relationships with maternal psychopathology. American Journal of Medical Genetics 114, 898–905.CrossRefGoogle ScholarPubMed
Walker, E.F., Sabuwalla, Z. & Huot, R. (2004). Pubertal neuromaturation, stress sensitivity, and psychopathology. Development and Psychopathology 16(4), 807–824.CrossRefGoogle ScholarPubMed
Weissman, M.M., Wolk, S., Wickramaratne, P., Goldstein, R.B., Adams, P., Greenwald, S., Ryan, N.D., Dahl, R.E. & Steinberg, D. (1999). Children with prepubertal-onset major depressive disorder and anxiety grown up. Archives of General Psychiatry 56, 794–801.CrossRefGoogle ScholarPubMed