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Understanding antipsychotic non-classical prescriptions: a quantitative and qualitative approach

Published online by Cambridge University Press:  11 April 2011

Antonio Veronese ,
Valerio Vivenza ,
Michela Nosè ,
Andrea Cipriani ,
Michele Tansella  and
Corrado Barbui
Antonio Veronese*
Affiliation:
Section of Psychiatry and Clinical Psychology, Department of Medicine and Public Health, University of Verona, Verona (Italy)
Valerio Vivenza
Affiliation:
Section of Psychiatry and Clinical Psychology, Department of Medicine and Public Health, University of Verona, Verona (Italy)
Michela Nosè
Affiliation:
Section of Psychiatry and Clinical Psychology, Department of Medicine and Public Health, University of Verona, Verona (Italy)
Andrea Cipriani
Affiliation:
Section of Psychiatry and Clinical Psychology, Department of Medicine and Public Health, University of Verona, Verona (Italy)
Michele Tansella
Affiliation:
Section of Psychiatry and Clinical Psychology, Department of Medicine and Public Health, University of Verona, Verona (Italy)
Corrado Barbui
Affiliation:
Section of Psychiatry and Clinical Psychology, Department of Medicine and Public Health, University of Verona, Verona (Italy)
*
Dr. A. Veronese, Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona (Italy). Fax: +39-045-585871 E-mail: [email protected]
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Summary

Aims – To date only a few studies investigated the clinical reasons supporting and explaining non-classical antipsychotic prescriptions. The present study was carried out to develop concepts which help understand this phenomenon in a natural setting, giving emphasis to views of clinicians according to quali – quantitative research methodologies. Subjects – From the South-Verona Psychiatric Case Register all antipsychotic prescriptions issued during 2005 were extracted. Concurrent prescribing of two or more antipsychotics, prescribing antipsychotic drugs outside the licensed indications, and outside the licensed ranges of doses reported in the Italian National Formulary, were considered non-classical prescriptions. Reasons for non-classical prescriptions were collected by means of brainstorming sessions with clinicians. Non-classical prescriptions and the corresponding reasons were grouped according to whether they were “clinically sound” or “clinically not sound”. Results – During 2005 a total of 259 patients received 376 non-classical prescriptions. The most frequently reported reasons for non-classical prescribing were that prescriptions were inherited from another clinician with or without benefit, and that prescriptions were motivated by the need of reducing psychotic symptoms. More than 60% of these non-classical prescriptions were categorised as “clinically sound”. Clinically not sound prescriptions were related with negative clinicians’ views and opinions about the patient/clinician relationship. Conclusion – Clinically not sound prescriptions appeared just a reflection of a problematic doctor/patient relationship, where no individual treatment plan existed and psychiatric visits had the only goal of monitoring ongoing prescriptions.

Declaration of Interest: This study received no funding. We have no conflicts of interest.

Keywords

antipsychoticsepidemiologycommunity psychiatric servicesirrational prescriptions
Type
Original Articles
Information
Epidemiology and Psychiatric Sciences , Volume 17 , Issue 3 , September 2008 , pp. 236 - 241
Copyright
Copyright © Cambridge University Press 2008

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