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Short-term depressive symptoms and 30-day prognosis of hospitalized patients with Acute Coronary Syndromes; the Greek Study of Acute Coronary Syndromes (GREECS)

Published online by Cambridge University Press:  18 May 2011

Christos Pitsavos ,
Demosthenes B. Panagiotakos ,
Sophia Arapi ,
George Giannopoulos ,
Constandina Masoura ,
Eleftherios Tsiamis  and
Christodoulos Stefanadis
Christos Pitsavos
Affiliation:
First Cardiology Clinic, School of Medicine, University of Athens, Athens (Greece)
Demosthenes B. Panagiotakos*
Affiliation:
Department of Dietetic-Nutrition, Harokopio University, Athens (Greece)
Sophia Arapi
Affiliation:
First Cardiology Clinic, School of Medicine, University of Athens, Athens (Greece)
George Giannopoulos
Affiliation:
First Cardiology Clinic, School of Medicine, University of Athens, Athens (Greece)
Constandina Masoura
Affiliation:
First Cardiology Clinic, School of Medicine, University of Athens, Athens (Greece)
Eleftherios Tsiamis
Affiliation:
First Cardiology Clinic, School of Medicine, University of Athens, Athens (Greece)
Christodoulos Stefanadis
Affiliation:
Department of Dietetic-Nutrition, Harokopio University, Athens (Greece)
*
Address for correspondence: Dr. D.B. Panagiotakos, 46 Paleon Polemiston St. 166 74 Glyfada, Attica (Greece). Fax: +30-2109600719 E-mail: [email protected]
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Summary

Aims – We evaluated whether short-term depressive symptoms are associated with the 30-day prognosis of hospitalized patients presented with acute coronary syndromes (ACS). Methods – A sample of 6 hospitals located in Greek urban and rural regions was selected. From October 2003 to September 2004, we recorded the non-fatal admissions of ACS. Assessment of depressive symptoms, during past month, was based on the CES-D scale (Radloff S., 1977). Results – 2172 patients were included in the study (1649, 76% were males). The mean CES-D score was 13.5±12 in male patients and 13.6±12 in females (p=0.89). Compared to patients with angina those who had non-Q-wave MI or Q-wave MI had higher CES-D score (12.3±11.6 vs. 15.3±12.8 vs. 13.2±11.9, p=0.001). The number of events during the first 30-day following discharge was 9.2% in males and 9.7% in females. Multivariable logistic regression analysis revealed that 1-unit increase in CES-D was associated with 10% higher odds (95% CI 1.09–1.12) of re-current events (death or re-hospitalization), after adjusting for various socio-demographic, lifestyle and clinical factors. Conclusion – We revealed that short-term depressive symptoms are related to more severe disease and a worsen 30-day prognosis of patients hospitalized for ACS.

Declaration of Interest: None.

Keywords

coronary syndromesdepressionGreeceepidemiology
Type
Original Articles
Information
Epidemiology and Psychiatric Sciences , Volume 16 , Issue 4 , December 2007 , pp. 309 - 315
Copyright
Copyright © Cambridge University Press 2007

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