Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-23T14:32:19.829Z Has data issue: false hasContentIssue false

Delusional belief flexibility and informal caregiving relationships in psychosis: a potential cognitive route for the protective effect of social support

Published online by Cambridge University Press:  25 October 2013

S. Jolley*
Affiliation:
King's College London, Institute of Psychiatry, Department of Psychology, University of London, UK
H. Ferner
Affiliation:
King's College London, Institute of Psychiatry, Department of Psychology, University of London, UK
P. Bebbington
Affiliation:
Department of Mental Health Sciences, UCL, London, UK
P. Garety
Affiliation:
King's College London, Institute of Psychiatry, Department of Psychology, University of London, UK
G. Dunn
Affiliation:
Health Sciences Research Group, School of Community Based Medicine, University of Manchester, UK
D. Freeman
Affiliation:
Department of Psychiatry, University of Oxford, Oxford, UK
D. Fowler
Affiliation:
School of Medicine, Health Policy and Practice, University of East Anglia, UK
E. Kuipers
Affiliation:
King's College London, Institute of Psychiatry, Department of Psychology, University of London, UK
*
*Address for correspondence: Dr S. Jolley, PO77 Department of Psychology, King's College London, Institute of Psychiatry, Denmark Hill, London, SE5 8AF, UK. (Email: [email protected])

Abstract

Aims.

For people with psychosis, contact with informal caregivers is an important source of social support, associated with recovery, and with better outcomes following individual cognitive therapy (CBTp). In this study, we tested whether increased flexibility in delusional thinking, an established predictor of positive outcome following CBTp, was a possible mechanism underlying this effect.

Methods.

219 participants with delusions (mean age 38 years; 71% male; 75% White) were grouped according to the presence of a caregiver (37% with a caregiver) and caregiver level of expressed emotion (High/Low EE, 64% Low). Delusional belief flexibility was compared between groups, controlling for interpersonal functioning, severity of psychotic symptoms, and other hypothesised outcome predictors.

Results.

Participants with caregivers were nearly three times more likely than those without to show flexibility (OR = 2.7, 95% CI 1.5 to 5.0, p = 0.001), and five times more likely if the caregiving relationship was Low EE (OR = 5.0, 95% CI 2.0–13.0, p = 0.001). ORs remained consistent irrespective of controlling for interpersonal functioning and other predictors of outcome.

Conclusions.

This is the first evidence that having supportive caregiving relationships is associated with a specific cognitive attribute in people with psychosis, suggesting a potential cognitive mechanism by which outcomes following CBTp, and perhaps more generally, are improved by social support.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Alloway, R, Bebbington, PE (1987). The buffer theory of social support: a review of the literature. Psychological Medicine 17, 91108.CrossRefGoogle ScholarPubMed
Amador, XF, Strauss, DH, Yale, SA, Flaum, MM, Endicott, J, Gorman, JM (1993). Assessment of insight in psychosis. American Journal of Psychiatry 150, 873879.Google Scholar
American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorders, 4th edn. American Psychiatric Association: Washington, DC.Google Scholar
Ammons, RB, Ammons, CH (1962). Quick Test. Psychological Test Specialists: Missoula, MT.Google Scholar
Ditzen, B, Heinrichs, M (2013). Psychobiology of social support: the social dimension of stress buffering. Restorative Neurology and Neuroscience, Epub ahead of print, doi: i10.3233/RNN-139008.Google Scholar
Fialko, L, Garety, PA, Kuipers, E, Dunn, G, Bebbington, PE, Fowler, D, Freeman, D (2008). A large-scale validation study of the Medication Adherence Rating Scale (MARS). Schizophrenia Research 100, 5359.Google Scholar
Freeman, D, Garety, PA, Fowler, DG, Kuipers, E, Bebbington, PE, Dunn, G (2004). Why do people with delusions fail to choose more realistic explanations for their experiences? An empirical investigation. Journal of Consulting and Clinical Psychology 72, 671689.Google Scholar
Freeman, D, Pugh, K, Vorontsova, N, Antley, A, Slater, M (2010). Testing the continuum of delusional beliefs: an experimental study using virtual reality. Journal of Abnormal Psychology 119, 8392.Google Scholar
Garety, PA, Fowler, D, Kuipers, E, Freeman, D, Dunn, G, Bebbington, P, Hadley, C, Jones, S (1997). The London-East Anglia randomised controlled trial of cognitive behaviour therapy for psychosis II: predictors of outcome. British Journal of Psychiatry 171, 420426.Google Scholar
Garety, PA, Freeman, D, Jolley, S, Dunn, G, Bebbington, PE, Fowler, DG, Kuipers, E, Dudley, R (2005). Reasoning, emotions, and delusional conviction in psychosis. Journal of Abnormal Psychology 114, 373384.Google Scholar
Garety, PA, Bebbington, P, Fowler, D, Freeman, D, Kuipers, E (2007). Implications for neurobiological research of cognitive models of psychosis: a theoretical paper. Psychological Medicine 37, 13771392.CrossRefGoogle ScholarPubMed
Garety, PA, Fowler, DG, Freeman, D, Bebbington, PE, Dunn, G, Kuipers, E (2008). Cognitive-behavioural therapy and family intervention for relapse prevention and symptom reduction in psychosis: a randomised controlled trial. British Journal of Psychiatry 192, 412423.CrossRefGoogle ScholarPubMed
Gayer-Anderson, C, Morgan, C (2013). Social networks, support and early psychosis: a systematic review. Epidemiology and Psychiatric Sciences 22, 131146.CrossRefGoogle ScholarPubMed
George, S, Bandopadhay, S, Cowan, C (2005). A case report of informal cognitive therapy of delusions by a carer: a novel treatment paradigm? European Psychiatry 20, 8081.Google Scholar
Haddock, G, McCarron, J, Tarrier, N, Faragher, EB (1999). Scales to measure dimensions of hallucinations and delusions: the psychotic symptom rating scales (PSYRATS). Psychological Medicine 29, 879889.CrossRefGoogle ScholarPubMed
Johns, L, Jolley, S, Keen, N, Peters, E (in press). CBT with people with psychosis. In Developing as a Cognitive Behavioural Therapist (ed. Grey, N. and Whittington, A.). Wiley: Chichester.Google Scholar
Kay, SR, Fiszbein, A, Opler, LA (1987). The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia. Schizophrenia Bulletin 13, 261276.Google Scholar
Kuipers, E, Onwumere, J, Bebbington, P (2010). Cognitive model of caregiving in psychosis. British Journal of Psychiatry 196, 259265.CrossRefGoogle ScholarPubMed
Lester, H, Marshall, M, Jones, P, Fowler, D, Amos, T, Khan, N, Birchwood, M (2011). Views of young people in early intervention services for first-episode psychosis in England. Psychiatric Services 62, 882887.Google Scholar
Mohamed, S, Rosenheck, R, McEvoy, J, Swartz, M, Stroup, S, Lieberman, JA (2009). Cross-sectional and longitudinal relationships between insight and attitudes toward medication and clinical outcomes in chronic schizophrenia. Schizophrenia Bulletin 35, 336346.Google Scholar
Norman, RM, Malla, AK, Manchanda, R, Harricharan, R, Takhar, J, Northcott, S (2005). Social support and three-year symptom and admission outcomes for first episode psychosis. Schizophrenia Research 80, 227234.Google Scholar
Norman, RM, Windell, D, Manchanda, R, Harricharan, R, Northcott, S (2012). Social support and functional outcomes in an early intervention program. Schizophrenia Research 140, 3740.Google Scholar
O'Brien, MP, Gordon, JL, Bearden, CE, Lopez, SR, Kopelowicz, A, Cannon, TD (2006). Positive family environment predicts improvement in symptoms and social functioning among adolescents at imminent risk for onset of psychosis. Schizophrenia Research 81, 269275.CrossRefGoogle ScholarPubMed
O'Brien, MP, Zinberg, JL, Bearden, CE, Lopez, SR, Kopelowicz, A, Daley, M, Cannon, TD (2008). Parent attitudes and parent adolescent interaction in families of youth at risk for psychosis and with recent-onset psychotic symptoms. Early Intervention in Psychiatry 2, 268276.Google Scholar
O'Brien, MP, Zinberg, JL, Ho, L, Rudd, A, Kopelowicz, A, Daley, M, Bearden, CE, Cannon, TD (2009). Family problem solving interactions and 6-month symptomatic and functional outcomes in youth at ultra-high risk for psychosis and with recent onset psychotic symptoms: a longitudinal study. Schizophrenia Research 107, 198205.Google Scholar
Onwumere, J, Kuipers, E, Bebbington, P, Dunn, G, Freeman, D, Fowler, D, Garety, P (2009). Patient perceptions of caregiver criticism in psychosis: links with patient and caregiver functioning. Journal of Nervous and Mental Disease 197, 8591.CrossRefGoogle ScholarPubMed
Onwumere, J, Kuipers, E, Bebbington, P, Dunn, G, Freeman, D, Fowler, D, Garety, P (2011). Coping styles in carers of people with recent and long-term psychosis. Journal of Nervous and Mental Disease 199, 423424.CrossRefGoogle ScholarPubMed
Riggio, HR, Kwong, WY (2011). Paranoid thinking, quality of relationships with parents, and social outcomes among young adults. Journal of Family Issues 32, 10301049.Google Scholar
Saha, S, Scott, J, Varghese, D, McGrath, J (2012). Social support and delusional-like experiences: a nationwide population-based study. Epidemiology and Psychiatric Sciences 21, 203212.Google Scholar
Schlosser, DA, Zinberg, JL, Loewy, RL, Casey-Cannon, S, O'Brien, MP, Bearden, CE, Vinogradov, S, Cannon, TD (2010). Predicting the longitudinal effects of the family environment on prodromal symptoms and functioning in patients at-risk for psychosis. Schizophrenia Research 118, 6975.CrossRefGoogle ScholarPubMed
Schrank, B, Amering, M, Grant Hay, A, Weber, M, Sibitz, I (2013). Insight, positive and negative symptoms, hope, depression and self-stigma: a comprehensive model of mutual influences in schizophrenia spectrum disorders. Epidemiology and Psychiatric Sciences, available on CJO2013. doi: i10.1017/S2045796013000322.Google Scholar
So, S, Freeman, D, Dunn, G, Kapur, S, Kuipers, E, Bebbington, P, Fowler, D, Garety, P (2012). Jumping to conclusions, a lack of belief flexibility and delusional conviction in psychosis. Journal of Abnormal Psychology 121, 129139.CrossRefGoogle ScholarPubMed
So, SH, Garety, PA, Peters, EP, Kapur, S (2010). Do antipsychotics improve reasoning biases? A review. Psychosomatic Medicine 72, 681693.Google Scholar
SPSS for Windows (2011). Version 20. IBM SPSS Statistics.Google Scholar
Sündermann, O, Onwumere, J, Bebbington, P, Kuipers, E (2013). Social networks and support in early psychosis: potential mechanisms. Epidemiology and Psychiatric Sciences 22, 147150.Google Scholar
Taylor, PJ, Garety, P, Buchanan, A, Reed, A, Wessely, S, Ray, K, Dunn, G, Grubin, D (1994). Delusions and violence. In Violence and Mental Disorder: Developments in Risk Assessment (ed. Monahan, J. and Steadman, H.), pp. 161182. University of Chicago Press: Chicago.Google Scholar
Tempier, R, Balbuena, L, Lepnurm, M, Craig, TK (2013). Perceived emotional support in remission: results from an 18-month follow-up of patients with early episode psychosis. Social Psychiatry and Psychiatric Epidemiology, Epub ahead of print, doi: i10.1007/s00127-013-0701-3.Google Scholar
Thoits, PA (2011). Mechanisms linking social ties and support to physical and mental health. Journal of Health and Social Behaviour 52, 145161.CrossRefGoogle ScholarPubMed
Tomlinson, E, Onwumere, J, Kuipers, E (2013). Distress and negative experiences of the caregiving relationship in early psychosis: does social cognition play a role? Early Intervention in Psychiatry, doi: i10.1111/eip.12040. Epub ahead of print.Google Scholar
van Baars, AW, Wierdsma, AI, Hengeveld, MW, Mulder, CL (2013). Improved insight affects social outcomes in involuntarily committed psychotic patients: a longitudinal study in the Netherlands. Comprehensive Psychiatry. doi: i10.1016/j.comppsych.2013.03.016. Epub ahead of print.Google Scholar
Vaughn, CE, Leff, JP (1976). The measurement of expressed emotion in the families of psychiatric patients. British Journal of Social and Clinical Psychology 15, 157165.Google Scholar
Waller, H, Freeman, D, Jolley, S, Dunn, G, Garety, P (2011). Targeting reasoning biases in delusions. Journal of Behaviour Therapy and Experimental Psychiatry 42, 414421.Google Scholar
Watson, PWB, Garety, PA, Weinman, J, Dunn, G, Bebbington, PE, Fowler, D, Freeman, D, Kuipers, E (2006). Emotional dysfunction in schizophrenia spectrum psychosis: the role of illness perceptions. Psychological Medicine 36, 761770.Google Scholar
Weaver, FM, Weaver, BA (2013). Does availability of informal care within the household impact hospitalisation? Health Economics, Policy and Law 8, 123.Google Scholar
Wessely, S, Buchanan, A, Reed, A, Cutting, J, Everitt, B, Garety, P, Taylor, PJ (1993). Acting on delusions (1): prevalence. British Journal of Psychiatry 163, 6976.CrossRefGoogle Scholar
World Health Organization (1992 a). The ICD–10 Classification of Mental and Behavioural Disorders: Clinical Description and Diagnostic Guidelines. WHO: Geneva.Google Scholar
World Health Organization (1992 b). SCAN: Schedules for Clinical Assessment in Neuropsychiatry. WHO: Geneva.Google Scholar