Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-22T15:55:40.616Z Has data issue: false hasContentIssue false
  • English
  • Français

Viruses in acute respiratory infection in a general community†

Published online by Cambridge University Press:  15 May 2009

J. E. Banatvala ,
T. B. Anderson  and
B. B. Reiss
J. E. Banatvala
Affiliation:
Polio Research Fund Fellow, Department of Pathology, Tennis Court Road, Cambridge
T. B. Anderson
Affiliation:
General practitioners, Cambridge
B. B. Reiss
Affiliation:
General practitioners, Cambridge
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The aetiology of acute respiratory infections between September 1962 and August 1963 was studied in two general practices in Cambridge. These practices were reasonably representative of the permanent community of Cambridge.

There were 592 spells of acute respiratory infection in the combined practices, representing an incidence of 11·4 spells per 100 persons. Children aged 0–4 had the highest rates (51·6 spells per 100 persons).

It was possible to establish a diagnosis in 62·5% of cases investigated. Influenza and parainfluenza infections featured prominently, being responsible between them for 46·6% of all respiratory infections investigated. From September 1962 to January 1963, parainfluenza viruses were prevalent, causing acute laryngo-tracheo-bronchitis in children (croup), and an influenza-like illness in adults. From February to April 1963, influenza A (Asian) was epidemic, a clinical diagnosis of influenza being frequently confirmed by laboratory studies at this time. There were nine cases of Eaton agent infection, seven of which had PAP, the other two being family contacts who later developed influenza-like illnesses.

Adenovirus (four cases), and RS virus (three cases) were not prevalent to any large extent in Cambridge during the survey.

Type
Research Article
Information
Journal of Hygiene , Volume 63 , Issue 1 , March 1965 , pp. 155 - 167
Copyright
Copyright © Cambridge University Press 1965

References

Andrew, J. D. & Gardner, P. S. (1963). Occurrence of respiratory syncytial virus in acute respiratory diseases in infancy. Brit. med. J. ii, 1447.CrossRefGoogle Scholar
Banatvala, J. E., Anderson, T. B. & Reiss, B. B. (1964). Parainfluenza infection in the community. Brit. med. J. i, 537.CrossRefGoogle Scholar
Beem, M., Wright, F. H., Hamre, D., Egerer, R. & Oehne, M. (1960). Association of chimpanzee coryza agent with acute respiratory disease in children. New Engl. J. Med. 263, 523.CrossRefGoogle ScholarPubMed
Bell, J. A., Huebner, R. J., Rosen, L., Rowe, W. P., Cole, R. M., Mastrota, F. M., Floyd, T. M., Chanock, R. M. & Shvedoff, R. A. (1961). Illness and microbial experience of nursery children at Junior Village. Amer. J. Hyg. 74, 267.Google Scholar
Bradstreet, C. M. P. & Taylor, C. E. D. (1962). Technique of complement-fixation test applicable to the diagnosis of virus diseases. Mon. Bull. Minist. Hlth Lab. Serv. 21, 96.Google Scholar
Chanock, R. M., Mufson, M. A., Bloom, H. H., James, W. D., Fox, H. H. & Kingston, J. R. (1961). Eaton agent pneumonia. J. Amer. med. Ass. 175, 213.CrossRefGoogle ScholarPubMed
Chanock, R. M., Parrott, R. H., Cook, K., Andrewes, B. E., Reichelderfer, T., Kapikian, A. Z., Mastrota, F. M. & Huebner, R. J. (1958). Newly recognized myxo-viruses from children with respiratory disease. New Engl. J. Med. 258, 207.CrossRefGoogle Scholar
Clarke, S. K. R., Corner, E. D., Gambier, D. M., Macrae, J. & Peacock, D. B. (1964). Viruses associated with acute respiratory infection. Brit. med. J. i, 1536.CrossRefGoogle Scholar
Davies, S. W. V. (1958). A year in general practice. Rep. Coll. gen. Pract. 1, 315.Google ScholarPubMed
Dingle, J. H., Badger, G. F., Feller, A. E., Hodges, G., Jordan, W. S. & Rammelkamp, C. U., Jr. (1953). Study of illness in a group of Cleveland families; plan of study and certain general observations. Amer. J. Hyg. 58, 16.Google Scholar
Fazekas de St Groth, S., Withell, J. & Lafferty, K. J. (1958). An improved assay method for neutralizing antibodies against influenza viruses. J. Hyg., Camb., 56, 415.CrossRefGoogle Scholar
Fry, J. (1957). Five years of general practice. A study in simple epidemiology. Brit. med. J. ii, 1453.CrossRefGoogle Scholar
Garrow, D. H. (1958). A rapid test for the presence of cold agglutinins. Brit. med. J. ii, 206.CrossRefGoogle Scholar
Goodburn, G. M., Marmion, B. P. & Kendall, E. J. C. (1963). Infection with Eaton's primary atypical pneumonia agent in England. Brit. Med. J. i, 1266.CrossRefGoogle Scholar
Grieble, H. G., Jackson, G. G., Dowling, H. F., Seketa, D. H. & Anderson, T. O. (1958). The etiology of common respiratory infections in a civilian adult population. Amer. J. med. Sci. 235, 245.CrossRefGoogle Scholar
Hamre, D. & Procknow, J. J. (1961). Viruses isolated from natural common colds in the U.S.A. Brit. med. J. ii, 1382.CrossRefGoogle Scholar
Heath, R. B., Tyrrell, D. A. J. & Peto, S. (1962). Serological studies with sendai virus. Brit. J. exp. Path. 43, 444.Google ScholarPubMed
Higgins, P. G., Ellis, E. M. & Boston, D. G. (1963). The isolation of viruses from acute respiratory infections. A study of the isolations made from cases occurring in general practice 1962. Mon. Bull. Minist. Hlth Lab. Serv. 22, 71.Google ScholarPubMed
Hilleman, M. R., Gauld, R. L., Butler, R. L., Stallones, R. A., Hedrerg, C. L., Warfield, M. S. & Anderson, S. A. (1957). Appraisal of occurrence of adenovirus-caused respiratory illness in military populations. Amer. J. Hyg. 66, 29.Google ScholarPubMed
Hilleman, M. R., Hamparian, V. V., Ketler, A., Reilly, C. M., McClelland, L., Cornfield, D. & Stokes, J., Jr. (1962). Acute respiratory illnesses amongst children and adults. J. Amer. med. Ass. 180, 445.CrossRefGoogle Scholar
Hobson, D. & Schild, G. C. (1960). Virological studies in natural common colds in Sheffield. Brit. med. J. ii, 1414.CrossRefGoogle Scholar
Jensen, K. E. (1961). Diagnosis of influenza by serologic methods. Amer. Rev. resp. Dis. 83, (2), pt. 2, 120.Google Scholar
Jordan, W. S., Badger, G. F., Curtiss, C, Dingle, J. H., Ginsberg, H. S. & Gold, E. (1956). A study of illness in a group of Cleveland families; the occurrence of adenovirus infections. Amer. J. Hyg. 64, 336.Google Scholar
Kendall, E. J. C., Riddle, R. W., Tuck, H. A., Rodan, K. S., Andrewes, B. E. & McDonald, J. C. (1957). Pharyngo-conjunctival fever. School outbreaks in England during the summer of 1955 associated with adenovirus types 3, 7 and 14. Brit. med. J. ii 131.CrossRefGoogle Scholar
Lewis, F. A., Rae, M. L., Lehmann, N. I. & Ferris, A. A. (1961). A syncytial virus association with epidemic disease of the lower respiratory tract in infants and young children. Med. J. Aust. 2, 932.CrossRefGoogle Scholar
Logan, W. P. D. & Cushion, A. A. (1958). Morbidity statistics in general practice. General Register Office, Studies on Medical and Population Subjects no. 14, vol. I. London: H.M.S.O.Google Scholar
Pemberton, J. (1949). Illness in general practice. Brit. med. J. i, 306.Google Scholar
Reilly, C. M., Hoch, S. M., Stokes, J. Jr, McClelland, L., Hamparian, V. V., Ketler, A. & Hilleman, M. R. (1962). Clinical and laboratory findings in cases of respiratory illness caused by coryzaviruses. Ann. intern. Med. 57, 515.CrossRefGoogle ScholarPubMed
Robinson, R. Q., Hoshiwara, I., Schaeffer, M., Gorrie, R. H. & Kaye, H. S. (1962). A survey of respiratory illnesses in a population. 1. Viral studies. Amer. J. Hyg. 75, 18.Google Scholar
Stuart-Harris, C. H. (1953). In Influenza and other Virus Infections of the Respiratory Tract. London: Edward Arnold and Co.Google Scholar
van der Veen, J. & Dijkman, J. H. (1962). Association of type 21 adenovirus with acute respiratory illness in military recruits. Amer. J. Hyg. 76, 149.Google ScholarPubMed
Vogel, J. & Shelokov, A. (1957). Adsorption-haemagglutination test for influenza virus in monkey kidney tissue culture. Science, 126, 358.CrossRefGoogle ScholarPubMed
W. H. O. Expert Committee on Influenza (1953). Tech. Rep. Wld Hlth Org. no. 64.Google Scholar
Woodall, J., Rowson, K. E. K. & McDonald, J. C. (1958). Age and Asian influenza 1957. Brit. med. J. ii, 1316.CrossRefGoogle Scholar
Woolridge, R. L., Grayston, J. Th., Whiteside, J. E., Loosli, C. G., Friedman, M. & Pierce, W. E. (1956). Studies in acute respiratory illness in naval recruits, with emphasis on the adenoviruses (APC-R1). J. infect. Dis. 99, 182.CrossRefGoogle Scholar