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Viruses in acute gastroenteritis in children in Pune, India

Published online by Cambridge University Press:  15 May 2009

P. Bright Singh ,
M. A. Sreenivasan  and
Khorshed M. Pavri
P. Bright Singh
Affiliation:
National Institute of Virology, 20-A, Dr Ambedkar Road, Pune-411 001, India
M. A. Sreenivasan
Affiliation:
National Institute of Virology, 20-A, Dr Ambedkar Road, Pune-411 001, India
Khorshed M. Pavri
Affiliation:
National Institute of Virology, 20-A, Dr Ambedkar Road, Pune-411 001, India
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A 2-year study from January 1981 to December 1982 was undertaken to determine the role of viruses in the causation of diarrhoea in hospitalized children in Pune, Maharashtra State, India. The stool samples of 426 children (213 diarrhoeal and 213 non-diarrhoeal controls) were investigated by electron microscopy and ELISA for the presence of viruses. Six morphologically distinct viruses were visualized: rotavirus, coronavirus-like particles (CVLP), adenovirus, astrovirus, calicivirus and small round virus-like particles (SRV). Rotavirus was detected in 28·6% of the diarrhoea! patients and in 1·4 % of the controls. The frequency of infection with rotavirus was highest in the children aged less than 5 years. The mean age of rotavirus-positive patients was 11 months. Although rotavirus was detected in almost every month, there has a seasonal trend for colder months when CVLP cases were fewest. However, the prevalence of CVLP was greater in the control group (23–0%) rather than in those with diarrhoea (8–9%). In the control group, CVLP were detected more frequently during the summer months. An inverse relationship between CVLP and rotavirus was observed in children. Adenovirus, astrovirus, calicivirus and SRV were detected in a small proportion of children with and without clinical symptoms of gastroenteritis.

Type
Research Article
Information
Epidemiology & Infection , Volume 102 , Issue 2 , April 1989 , pp. 345 - 353
Copyright
Copyright © Cambridge University Press 1989

References

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