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Variation in virulence of bovine rotaviruses

Published online by Cambridge University Press:  19 October 2009

J. C. Bridger  and
D. H. Pocock
J. C. Bridger
Affiliation:
Agricultural and Food Research Council, Institute for Research on Animal Diseases, Compton, Newbury, Berkshire, RB16 0NN
D. H. Pocock
Affiliation:
Agricultural and Food Research Council, Institute for Research on Animal Diseases, Compton, Newbury, Berkshire, RB16 0NN
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Summary

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Forty-six gnotobiotic calves aged less than 16 days or 42–116 days were infected with three strains of bovine rotavirus designated C3–160, CP-1 and PP-1. Each virus was passaged and cloned in cell culture (cloned viruses) but CP-1 and PP-1 Were also used before culture (faecal viruses).

Infection of calves aged less than 16 days with faecal or cloned CP-1 caused disease whereas cloned C3–160 and faecal or cloned PP-1 caused subclinical infections. The clinical signs of disease were change in faecal colour to pale yellow or cream, increase of 2- to 7-fold in the volume of faecal output and, usually, anorexia. With the virulent CP-1 virus and the avirulent C3–160, similar amounts of virus were excreted in the faeces for 4–6 days.

Infection of calves aged 56–116days with faecal CP-1 produced disease of similar severity to that seen in calves aged 7–10 days infected with the same virus. No differences in clinical signs, virus excretion or levels of convalescent antibody were seen between the two groups. With cloned CP-1, 5 of 8 older calves developed disease but 3 showed only mild signs of infection.

It was concluded that two strains of rotavirus caused sub-clinical infections in young calves while a third was virulent in calves up to at least 116 days of age.

Type
Research Article
Information
Journal of Hygiene , Volume 96 , Issue 2 , April 1986 , pp. 257 - 264
Copyright
Copyright © Cambridge University Press 1986

References

REFERENCES

Acres, S. D. & Babiuk, L. A. (1978). Studies on rotavirus antibody in bovine serum and lacteal secretions, using radioimmunoassay. Journal of the American Veterinary Association 173, 555–559.Google ScholarPubMed
Bridger, J. C. (1978). Location of type-specific antigens in calf rotaviruses. Journal of Clinical Microbiology 8, 625–628.CrossRefGoogle ScholarPubMed
Bridger, J. C. & Brown, J. F. (1981). Development of immunity to porcine rotavirus in piglets protected from disease by bovine colostrum. Infection and Immunity 31, 906–910.CrossRefGoogle ScholarPubMed
Bridger, J. C. & Brown, J. F. (1984). Antigen and pathogenic relationships of three bovine rotaviruses and a porcine rotavirus. Journal of General Virology 65, 1151–1158.CrossRefGoogle Scholar
Bridger, J. C.Hall, G. A. & Brown, J. F. (1984). Characterisation of a calici-like virus (Newbury agent) found in assocation with astrovirus in bovine diarrhoea. Infection and Immunity 43, 133–138.CrossRefGoogle Scholar
Bridger, J. C. & Woode, G. N. (1975). Neonatal calf diarrhoea: identification of a reovirus-like (rotavirus) agent in faeces by immunofluorescence and immune electron microscopy. British Veterinary Journal 131, 528–535.CrossRefGoogle ScholarPubMed
Carpio, M., Bellamyu, J. E. C. & Babiuk, L. A. (1981). Comparative virulence of different bovine rotavirus isolates. Canadian Journal of Comparative Medicine 45, 38–42.Google ScholarPubMed
De Leeuw, P. W., Ellens, D. J., Straver, P. J., Van Balkan, J. A. M., Moerman, A. & Baanvinoer, T. (1980). Rotavirus infections in calves in dairy herds. Research in Veterinary Science 29, 135–141.CrossRefGoogle ScholarPubMed
Dennis, M. J., Davies, D. C. & Hoare, M. N. (1976). A simplified apparatus for the microbiological isolation of calves. British Veterinary Journal 132, 642–646.CrossRefGoogle ScholarPubMed
Echeverria, P., Blacklow, N. R., Cukor, G. C.Vibulbandhitklt, S., Changehawalit, S. & Boonthai, P. (1983). Rotavirus as a cause of severe gastroenteritis in adults. Journal of Clinical Microbiology 18, 663–667.CrossRefGoogle ScholarPubMed
Gouet, P., Contrepois, M., C., Durourgier. H., Riou, Y. & Scherrer, R. (1978). The experimental production of diarrhoea in colostrum deprived axenic and gnotoxenic calves with enteropathogenic E. coli, rotavirus, coronavirus and in combined infection of rotavirus and E. coli. Annales de Recherche Veterinaire 9, 433–440.Google ScholarPubMed
Hall, G. A., Bridger, J. C., Chandler, R. L. & Woode, G. N. (1976). Gnotobiotic piglets experimentally infected with neonatal calf diarrhoea reovirus-like agent (rotavirus). Veterinary Pathology 13, 197–210.CrossRefGoogle ScholarPubMed
Hoare, M. N., Davies, D. C. & Dennis, M. J. (1976) The derivation of gnotobiotic calves by a hyaterotomy and slaughter technique. British Veterinary Journal 132, 369–373.CrossRefGoogle ScholarPubMed
Linhares, A. C., Pinheiro, F. P., Freitas, R. B., Gabbay, Y. B., Shirley, J. A. & Beards, G. M. (1981). An outbreak of rotavirus diarrhea among a non-immune, isolated South American Indian community. American Journal of Epidemiology 113, 703–710.CrossRefGoogle Scholar
McNulty, M. S. & Logan, E. F. (1983). Longitudinal survey of rotavirus infection in calves. Veterinary Record 113, 333–335.CrossRefGoogle ScholarPubMed
Riepenhoff-Talty, M., Lee, P., Carmody, P. J., Barrett, H. J. & Ogra, P. L. (1982). Age-dependent rotavirus enterocy to interactions. Proceedings of the Society for Experimental Biology and Medicine 170, 146–154.CrossRefGoogle ScholarPubMed
Runnels, P. L., Moon, H. W., Whipp, S. C., Matthews, P. J. & Woode, G. N. (1980). Interaction of rotavirus and enterotoxigenic E. coli (ETEC) in gnotobiotic calves. Proceedings of the Third International Symposium on Neonatal Diarrhea, pp. 343–358. Canada: University of Saskatchewan.Google Scholar
Schusser, G., Hinaidy, B. & Bürki, F. (1982). A follow-up study on bovine rotavirus dissemination among calves of a large dairy herd. Microbiologica 5, 321–332.Google ScholarPubMed
Sheridan, J. F., Eydelloth, R. S., Vonderfecht, S. L. & Aurelian, L. (1983). Virus specific immunity in neonatal and adult mouse rotavirus infection. Infection and Immunity 39, 917–927.CrossRefGoogle ScholarPubMed
Sibalin, M., Szerkely, H. & Bürki, F. (1980). Rotavirusinfektionen in einem grüsseren Rhinderbestand. Weiner Tierärztliche Monatatsschrift 67, 122–127.Google Scholar
Snodgrass, D. R. & Wells, P. W. 1976. Rotavirus infection in lambs: studies on passive protection. Archives of Virology 52, 201–205.CrossRefGoogle ScholarPubMed
Tzipori, S. R., Makin, T. J., Smith, M. L. & Krautil, F. L. (1981). Clinical manifestations of diarrhoea in calves infected with rotavirus and enterotoxigenic Escherichia coli. Journal of Clinical Microbiology 13, 1011–1016.CrossRefGoogle ScholarPubMed
Van Opdenbosch, E. & Wellemans, G. (1982). Perspectives in the prevention of viral neonatal calf diarrhoea. Proceedings of the XIIth World Congress on Diseases of Cattle, p. 374.Google Scholar
Wolf, J. L., Cukor, G., Blacklow, N. R., Dambrauskas, R. & Trier, J. S. (1981). Susceptibility of mice to rotavirus infection: effects of age and administration of corticosteroids. Infection and Immunity 33, 565–574.CrossRefGoogle ScholarPubMed
Woode, G. N., Bridger, J. C., Hall, G. A. & Dennis, M. J. (1974). The isolation of a reovirus-like agent associated with diarrhoea in colostrum-deprived calves in Great Britain. Research in Veterinary Science 16, 102–105.CrossRefGoogle ScholarPubMed
Woode, G. N. & Bridger, J. C. (1975). Viral enteritis of calves. Veterinary Record 96, 85–88.CrossRefGoogle ScholarPubMed