Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-05T15:43:46.107Z Has data issue: false hasContentIssue false
  • English
  • Français

Vaccination of adults with Wistar RA 27/3 rubella vaccine

Published online by Cambridge University Press:  15 May 2009

D. S. Freestone ,
J. Prydie ,
S. G. Hamilton Smith  and
G. Laurence
D. S. Freestone
Affiliation:
Departments of Clinical Immunology and of Virology, the Wellcome Research Laboratories, Beckenham, Kent
J. Prydie
Affiliation:
Departments of Clinical Immunology and of Virology, the Wellcome Research Laboratories, Beckenham, Kent
S. G. Hamilton Smith
Affiliation:
Departments of Clinical Immunology and of Virology, the Wellcome Research Laboratories, Beckenham, Kent
G. Laurence
Affiliation:
Departments of Clinical Immunology and of Virology, the Wellcome Research Laboratories, Beckenham, Kent
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Thirty-three adults were vaccinated subcutaneously with Wistar RA. 27/3 (live attenuated) rubella vaccine at the Wellcome Research Laboratories, Beckenham. All subjects with pre-vaccination haemagglutinating-inhibiting antibody titres of 1/20 or less and three of seven subjects with pre-vaccination titres of 1/40 showed at least fourfold rises of titre. Reactions encountered were mild and of short duration.

Type
Research Article
Information
Journal of Hygiene , Volume 69 , Issue 3 , September 1971 , pp. 471 - 477
Copyright
Copyright © Cambridge University Press 1971

References

REFERENCES

Cooper, L. A. & Krugman, S. (1966). Diagnosis and management in congenital rubella Pediatrics 37, 335.CrossRefGoogle ScholarPubMed
Cooper, L. S., Ziring, P. R., Weiss, J., Matters, B. A. & Krugman, S. (1969). Transient arthritis after rubella vaccination. American Journal of Diseases of Children 118, 218.Google ScholarPubMed
Dudgeon, J. A., Marshall, W. C., Peckham, C. S. & Hawkins, G. T. (1969). Clinical and laboratory studies with rubella vaccines in adults. British Medical Journal i, 271.CrossRefGoogle Scholar
Feldman, H. A. (1968). Removal by heparin-MnCl2 of non-specific rubella haemagglutinin serum inhibitor. Proceedings of the Society for Experimental Biology and Medicine 127, 570.CrossRefGoogle Scholar
Mann, J. J., Rossen, R. D., Lehrich, J. R. & Kasel, J. A. (1967). The effect of kaolin on immunoglobulins: an improved technique to remove the non-specific serum inhibitor of reovirus haemagglutination. Journal of Immunology 98, 1136.CrossRefGoogle Scholar
Oski, F. A. & Naiman, J. L. (1966). Effect of live measles vaccine on the platelet count. New England Journal of Medicine 275, 352.CrossRefGoogle ScholarPubMed
Peetermans, J. & Huygelen, C. (1967). L'emploi d'hérmaties de pigeons dans le test d'inhibition de l'hémagglutination de la rubéole. Presse Médicale 75, 2177.Google Scholar
Plotkin, S. A., Cornfeld, D. & Ingalls, T. H. (1965). Studies of immunization with living rubella virus. American Journal of Diseases of Children 110, 381.CrossRefGoogle ScholarPubMed
Plotkin, S. A., Farquhar, J., Katz, M. & Ingalls, T. H. (1967). A new attenuated rubella virus grown in human fibroblasts: evidence for reduced nasopharyngeal excretions. American Journal of Epidemiology 86, 468.CrossRefGoogle Scholar
Plotkin, S. A., Bechtel, D. J. & Sedwick, W. D. (1968). A simple method for removal of rubella haemagglutination inhibitors from serum, adaptable to finger-tip blood. American Journal of Epidemiology 88, 301.CrossRefGoogle ScholarPubMed
Stewart, G. L., Parkman, P. D., Mopps, M. E., Douglas, R. D., Hamilton, J. P. & Meyer, H. M. (1967). Rubella virus haemagglutination inhibition test. New England Journal of Medicine 276, 554.CrossRefGoogle Scholar