Hostname: page-component-7bb8b95d7b-fmk2r Total loading time: 0 Render date: 2024-09-13T14:18:11.381Z Has data issue: false hasContentIssue false

The Treatment of Mediterranean Fever by means of Vaccines, with Illustrative Cases

Published online by Cambridge University Press:  15 May 2009

Fleet-Surgeon P. W. Bassett-Smith
Affiliation:
Royal Naval Hospital, Haslar.
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

For years we have been vainly striving to find some method of treatment capable of preventing or cutting short the relapses so constantly present in Mediterranean fever. Though certain drugs have for a time seemed successful, their beneficial effects are usually uncertain and transient, so that the treatment of the disease has come to be almost entirely symptomatic. Many germicides have been tried; among these “cyllin” has lately been said to shorten the course of the fever. In my hands this has not been the case. Burney Yeo's chlorine and quinine mixture has here occasionally produced very satisfactory results when given with a rising temperature, apparently cutting short a wave of pyrexia, which from experience we had expected to last ten days or more; but its action is very uncertain.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1907

References

REFERENCES

Bassett-Smith, (1902). “The agglutinating properties of the blood in cases of Mediterranean fever, and other changes and reactions found in the course of the disease.” Brit. Med. Journ. Vol. II. p. 861.Google Scholar
Bassett-Smith, (1906). “Critical examination of blood of patients in hospital to determine if other than Mediterranean fever sera would agglutinate the Micrococcus melitensis.” Mediterranean Fever Commission Report to the Royal Society, London, Part IV. 1906.Google Scholar
Birt, and Lamb, (1899). “Malta fever, with special reference to specific agglutinating substances found in the blood.” Lancet, Vol. II. p. 701.CrossRefGoogle Scholar
Bullock, (1905). “On the principles underlying the treatment of bacterial diseases by the inoculation of the corresponding vaccine.” Practitioner, November.Google Scholar
Dean, (1905). “An experimental inquiry into the nature of the substance in serum which influences phagocytosis.” Proc. Royal Society, Vol. B. 76, p. 506.Google Scholar
French, (1906). “On opsouic factors, their estimation and uses in therapeutics.” Practitioner, July.Google Scholar
Haggard, and Morland, (1905). “The action of yeast on tuberculosis and its influence on the osponic index.” Lancet, Vol. I. p. 1493.CrossRefGoogle Scholar
Leishman, (1905). “Experiments in connection with stimulins.” Trans. Pathol. Soc. London, July.Google Scholar
Leishman, (1905). “Anti-typhoid inoculations.” Journ. Hygiene, Vol. V. p. 380.CrossRefGoogle Scholar
Metchnikoff, (1906). Harben Lecture, 1906. “The hygiene of the tissues.” Journ. R. Inst. Pub. Health, June.Google Scholar
Reid, (1906). “Malta fever inoculations.” Trans. Pathol. Soc. Lond. Vol. LVII. p. 463.Google Scholar
Wright, (1902). “Notes on the treatment of furunculosis, etc., by the inoculation of vaccines; and generally on the treatment of localised bacterial infections by therapeutic inoculations of corresponding bacterial vaccines.” Lancet, Vol. I. p. 874.CrossRefGoogle Scholar
Wright, and Douglas, (1903). “An experimental investigation of the role of the blood fluids in connection with phagocytosis.” Proc. Royal Soc. London, Vol. LXXII. p. 357.Google Scholar
Wright, and Douglas, (1904). “Further observations on the rôle of the blood in connection with phagocytosis.” Proc. Royal Soc. London, Vol. LXXIII. p. 128.CrossRefGoogle Scholar
Wright, and Douglas, (1905). “On the general principles of the therapeutic inoculations of bacterial vaccines.” Lancet, Vol. II. pp. 1598 and 1674.CrossRefGoogle Scholar