Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-22T15:05:05.887Z Has data issue: false hasContentIssue false

Toxoplasmin sensitivity: subnormality and environment

Published online by Cambridge University Press:  15 May 2009

J. S. Robertson
Affiliation:
50 Holydyke, Barton-on-Humber
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The incidence of positive toxoplasmin skin test among subnormals in hospital was compared with that in subnormals attending day training centres and among normal children taken into County Council children's homes. Twelve out of 120 subnormals below the age of 20 attending day training centres were positive to the test, and 23 were positive out of 233 subnormals of the same age tested in hospital.

There was only 1 positive out of 71 children under the age of 18 in the County Council children's homes, compared with 29 out of 296 subnormals of this age who were tested.

The incidence of positive skin test among 115 mongols under the age of 50 was about 11% in each age range, whereas that in 709 other subnormals rose from 5% in those below the age of 10 to 30% in those over the age of 30.

Although factors similar to those causing admission of normal children to County Council care often determine the admission of subnormals to hospital, the children in County Council homes did not share the high incidence of infection which was found in subnormals.

It is suggested that the majority of infections among subnormal children are postnatally acquired. Since the incidence was the same in subnormals living at home as among those in hospital it is suggested that some personal habit commoner among subnormal than among normal children exposes the subnormals to an increased risk of infection.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1966

References

REFERENCES

Beattie, C. P. (1964). Toxoplasmosis. Lister Fellowship Lecture. Publs R. Coll. Physns Edinb. no. 28.Google Scholar
Burkinshaw, J., Kirman, B. H. & Sorsby, A. (1953). Toxoplasmosis in relation to mental deficiency. Br. med. J. i, 702–4.CrossRefGoogle Scholar
Cooke, I. & Derrick, E. H. (1961). The incidence of toxoplasma antibodies in mental hospital patients. Australas. Ann. Med. 10, 137–41.CrossRefGoogle Scholar
Desmonts, G., Couvreur, J. & Ben, Rachid M.-S. (1965). Le toxoplasme, la mère et l'enfant. Archs. fr. Pédiat. 22, 11831200.Google Scholar
Desmonts, G., Couvreur, J., Alison, F., Baudelot, J., Gerbeaux, J. & Lelong, M. (1965). Étude épidémiologique sur la toxoplasmose. Rev. fr. Étud. clin. biol. 10, 952–8.Google Scholar
Fleck, D. G. (1963). Epidemiology of toxoplasmosis. J. Hyg., Camb. 61, 61–5.CrossRefGoogle ScholarPubMed
Hutchison, W. M. (1965). Experimental transmission of Toxoplasma gondii. Nature, Lond. 206, 961–2.CrossRefGoogle ScholarPubMed
Jirovec, O., Jira, J., Fuchs, V. & Peter, R. (1957). Studien mit dem Toxoplasmintest. Zentbl. Bakt. ParasitKde, Abt. 1, Orig. 169, 129–59.Google Scholar
Labzoffsky, N. A., Fish, N.A., Gyulai, E. & Roughley, F. (1965). A survey of toxoplasmosis among mentally retarded children. Can. med. Ass. J. 92, 1026–8.Google ScholarPubMed
Langer, H. (1963). Repeated congenital infection with Toxoplasma gondii. Obstet. Gynec., N.Y. 21, 318–29.Google ScholarPubMed
Remington, J. S., Newell, J. W. & Cavanaugh, E. (1964). Spontaneous abortion and chronic toxoplasmosis. Obstet. Gynec., N.Y. 24, 2531.Google ScholarPubMed
Robertson, J. S. (1965). Toxoplasma skin- and dye-test surveys of severely subnormal patients in Lincolnshire. J. Hyg., Camb. 63, 8998.CrossRefGoogle ScholarPubMed
Robertson, J. S. (1966). Chronic toxoplasmosis with negative dye-test? Post-grad. med. J. 42, 61–4.CrossRefGoogle ScholarPubMed
Stoller, A. & Collmann, R. D. (1965). Incidence of infective hepatitis followed by Down's syndrome nine months later. Lancet ii, 1221–3.CrossRefGoogle Scholar
Thalhammer, O. (1962). Congenital toxoplasmosis. Lancet i, 23–4.CrossRefGoogle Scholar
Werner, H., Schmidtke, L. & Thomascheck, G. (1963). Toxoplasma-Infektion und Schwangerschaft. Klin. Wschr. 41, 96101.CrossRefGoogle Scholar