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Successful control of a school based measles outbreak by immunization

Published online by Cambridge University Press:  15 May 2009

R. A. Lyons ,
H. I. Jones  and
R. L. Salmon
R. A. Lyons
Affiliation:
PHLS Communicable Disease Surveillance Centre (Welsh Unit), Abton House, Wedal Road, Cardiff CF4 3QX
H. I. Jones
Affiliation:
Gwynedd Health Authority, Coed Mawr, Bangor, Gwynedd LL57 4TP
R. L. Salmon*
Affiliation:
PHLS Communicable Disease Surveillance Centre (Welsh Unit), Abton House, Wedal Road, Cardiff CF4 3QX
*
* Author for correspondence.
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Summary

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In an outbreak of measles in North Wales centred on a secondary school in 1991, 74 cases occurred over a period of 51 days. Before the outbreak started, 27 % pupils did not have a history of measles or immunization and were considered susceptible. Active case rinding and identification and vaccination of susceptible contacts commenced after the fourth generation of cases and further reduced the pool of susceptible schoolchildren from 17%, at the onset of the vaccination campaign, to 8%. A fifth generation of cases did not occur. Delays in diagnosis (mean 2·8 days) and notification (mean 6·1 days) hampered control. There was no evidence of primary vaccine failure (observed vaccine efficacy 97%). Sixty-nine (93%) cases were considered preventable. Reasons for the apparent success of the intervention are discussed.

Type
Research Article
Information
Epidemiology & Infection , Volume 113 , Issue 2 , October 1994 , pp. 367 - 375
Copyright
Copyright © Cambridge University Press 1994

References

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