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A study of HPV 1, 2 and 4 antibody prevalence in patients presenting for treatment with cutaneous warts to general practitioners in N. Ireland

Published online by Cambridge University Press:  15 May 2009

K. Steele ,
P. V. Shirodaria ,
H. Pfister ,
B. Pollock ,
P. Fuchs ,
J. D. Merrett ,
W. G. Irwin  and
D. I. H. Simpson
K. Steele
Affiliation:
Departments of General PracticeThe Queen's University of Belfast, 1 Dunluce Avenue, Belfast, BT9 7HR
P. V. Shirodaria
Affiliation:
Departments of Microbiology and ImmunobiologyThe Queen's University of Belfast, 1 Dunluce Avenue, Belfast, BT9 7HR
H. Pfister
Affiliation:
Institute of Virology, University of Erlangen, Erlangen–Nurnberg, West Germany
B. Pollock
Affiliation:
Departments of Microbiology and ImmunobiologyThe Queen's University of Belfast, 1 Dunluce Avenue, Belfast, BT9 7HR
P. Fuchs
Affiliation:
Institute of Virology, University of Erlangen, Erlangen–Nurnberg, West Germany
J. D. Merrett
Affiliation:
Departments of Medical Statistics, The Queen's University of Belfast, 1 Dunluce Avenue, Belfast, BT9 7HR
W. G. Irwin
Affiliation:
Departments of General PracticeThe Queen's University of Belfast, 1 Dunluce Avenue, Belfast, BT9 7HR
D. I. H. Simpson
Affiliation:
Departments of Microbiology and ImmunobiologyThe Queen's University of Belfast, 1 Dunluce Avenue, Belfast, BT9 7HR
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Three hundred and seventy-six patients attending their general practitioner with cutaneous warts at five health centres in Northern Ireland were screened for human papilloma virus (HPV) types 1 and 2 IgM antibody using an indirect immunofluorescence test. Eighty-eight (23·4%) patients were positive for HPV type 1 IgM and 156 (41·5%) for HPV type 2 IgM. HPV 1 IgM antibody was significantly more likely to be associated with plantar warts than warts elsewhere (P 0·0001). HPV 2 IgM was present in 45 (34·1%) patients with plantar warts and 99 (45·6%) patients with warts at other sites (P=0·1). Evidence of multiple infection by HPV types 1 and 2 was demonstrated by the finding of HPV 1 and 2 IgM antibodies in the sera of 16 (4·3%). HPV 4 was found in only 1 out of 30 biopsies and HPV 4 IgM was undetectable in 50 randomly chosen sera.

Type
Research Article
Information
Epidemiology & Infection , Volume 101 , Issue 3 , December 1988 , pp. 537 - 546
Copyright
Copyright © Cambridge University Press 1988

References

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