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A study of foot-and-mouth disease virus strains by complement fixation: II. A comparison of tube and microplate tests for the differentiation of strains

Published online by Cambridge University Press:  15 May 2009

A. J. Forman
A. J. Forman
Affiliation:
Animal Virus Research Institute, Pirbright, Woking, Surrey, GU24 0NF
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Summary

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Several foot-and-mouth disease virus strains were examined by complement-fixation tests in microplates and in tubes. It was established that the two systems are comparable, although greater reproducibility is obtained with tube tests. While microplate tests are a satisfactory method for the differentiation of strains, tube tests provide a more precise method for the identification of small antigenic differences.

Type
Research Article
Information
Journal of Hygiene , Volume 72 , Issue 3 , June 1974 , pp. 407 - 413
Copyright
Copyright © Cambridge University Press 1974

References

REFERENCES

Brooksby, J. B. (1952). The technique of complement-fixation in foot-and-mouth disease research. Agricultural Research Council Report Series No. 12. London: H.M. Stationery Office.Google Scholar
Brown, F. & Cartwright, B. (1963). Purification of radioactive foot-and-mouth disease virus. Nature, London 199, 1168–70.CrossRefGoogle ScholarPubMed
Forman, A. J. (1974). A study of foot-and-mouth disease virus strains by complement fixation. I. A model for the fixation of complement by antigen/antibody mixtures. Journal of Hygiene 72, 397.CrossRefGoogle Scholar
Guerche, J., Durand, M., Giraud, M., Colson, X. & Prunet, P. (1972). Variants of foot-and-mouth disease virus: comparative study of serological and immunological differentiation. Report No. 600, XIII Conference of the Permanent Committee on Foot-and-Mouth Disease.Paris:Office International des Epizooties.Google Scholar
Priston, R. (1972). A study of the biological and physical properties of some induced mutants of.foot-and-mouth disease virus. Ph.D. Thesis, University of London.Google Scholar
Ubertini, B., Nardelli, L., Dal Prato, A., Panina, G. & Santero, G. (1964). Subtype variation of foot-and-mouth disease virus and vaccination. Wiener tierarztliche Monatsschrift 51 (Suppl.), 99–110.Google Scholar