Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-22T15:22:56.143Z Has data issue: false hasContentIssue false
  • English
  • Français

Studies on vaccinia haemagglutinin: I. Some physico-chemical properties

Published online by Cambridge University Press:  15 May 2009

C. M. Chu
C. M. Chu
Affiliation:
Department of Pathology, University of Cambridge
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Specific vaccinia haemagglutinin has been identified in vaccinia materials derived from chick embryo, rabbit skin, rabbit testis and sheep skin.

2. The haemagglutinin is distinct from, and apparently unassociated with, the elementary bodies.

3. Centrifugation studies indicate that the haemagglutinin activity is associated with particles of the order of 65 μ in diameter and having an approximate density value of 1·;1.

4. Vaccinia haemagglutinin retains its haemagglutinating activity after boiling for 10 min. It is stable within the pH range 5·92–9·79.

5. The behaviour of vaccinia haemagglutinin to various chemical procedures and an attempt at its purification are described.

Type
Research Article
Information
Journal of Hygiene , Volume 46 , Issue 1 , March 1948 , pp. 42 - 48
Copyright
Copyright © Cambridge University Press 1948

References

REFERENCES

Beveridge, W. I. B. & Burnet, F. M. (1946). Spec. Rep. Ser. Med. Res. Coun., Lond., no. 256.Google Scholar
Burnet, F. M. (1946). Nature, Lond., 158, 119.CrossRefGoogle Scholar
Burnet, F. M. & Stone, J. D. (1946). Aust. J. Exp. Biol. Med. Sci. 24, 1.CrossRefGoogle Scholar
Clark, E. & Nagler, F. P. O. (1943). Aust. J. Exp Biol. Med. Sci. 21, 103.CrossRefGoogle Scholar
Craigie, J. (1932). Brit. J. Exp. Path. 13, 259.Google Scholar
Elford, W. J. (1938). Handbuch der Virusforschung, 1, 126.CrossRefGoogle Scholar
McFarlane, A. S. & Kekwick, R. A. (1942). M.R.C. Blood Transfusion Research Committee, B.T. 17.Google Scholar
Nagler, F. P. O. (1942). Med. J. Aust. 1, 281.CrossRefGoogle Scholar
Nagler, F. P. O. (1944). Aust. J. Exp. Biol. Med. Sci. 22, 29.CrossRefGoogle Scholar
North, E. A. (1944). Aust. J.Exp. Biol.Med. Sci. 22, 105.CrossRefGoogle Scholar
Parker, R. F. & Rivers, T. M. (1935). J. Exp. Med. 62, 65.CrossRefGoogle Scholar
Schlesinger, M. (1934). Kolloidzschr. 67, 135.Google Scholar
Stone, J. D. (1946 a). Aust. J. Exp. Biol. Med. Sci. 24, 197.CrossRefGoogle Scholar
Stone, J.D. (1946 b). Aust. J. Exp. Biol. Med. Sci. 24, 191.CrossRefGoogle Scholar
Stone, J. D. & Burnet, F. M. (1946). Aust. J. Exp. Biol. Med. Sci. 24, 9.CrossRefGoogle Scholar