Published online by Cambridge University Press: 15 May 2009
In the Berkefeld filtration of a fresh guinea-pig serum, adsorption on the filter surface takes place, and the serum passes unaltered, if the saturation of the adsorbing surface has become complete.
This adsorption involves most probably first the albumins, which process then secondly influences the filtrability of the globulins. It is also shown that the physical conditions of the serum as regards salt concentration and dilution as well as H.-concentration modify the effect of filtration to a large extent.