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Studies on the agent of canine virus hepatitis (Rubarth's disease) I. Complement-fixation and precipitin tests

Published online by Cambridge University Press:  19 October 2009

N. M. Larin
Affiliation:
From the Canine Research Station of the Animal Health Trust, Kennett, Newmarket
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The preparation of purified antigen from canine hepatitis virus sources is described. This includes the manufacture of crude antigenie suspensions and their subsequent treatment to remove non-specific interfering substances.

The solubility of the antigenie substance in various solvents has been studied and its stability is briefly discussed.

The complement-fixation and precipitin tests are described in detail as they have been used for the virus studies.

Various virus-rich body tissues and fluids have been serologically tested, and the identity of antigens prepared from them as well as the antigenie similarity of the various strains of canine hepatitis virus have been established.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1951

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