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Studies on respiratory infection: III. Experiments with Brucella suis

Published online by Cambridge University Press:  15 May 2009

H. A. Druett
Affiliation:
Microbiological Research Department, Porton, near Salisbury, Wiltshire
D. W. Henderson
Affiliation:
Microbiological Research Department, Porton, near Salisbury, Wiltshire
S. Peacock
Affiliation:
Microbiological Research Department, Porton, near Salisbury, Wiltshire
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The infectivity of Brucella suis for the guinea-pig by the respiratory route has been studied. Br. Suis was dispersed in airborne particles of various sizes from single organisms to 12μ in diameter, and it was found that the infectivity decreased 600-fold with increasing particle size within this range. It is suggested that this is due to the ability of Br. Suis to multiply rapidly on the surface of the lower reaches of the respiratory tract.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1956

References

REFERENCES

Druett, H. A. (1952). Bacterial invasion. Nature, Lond., 170, 288.CrossRefGoogle ScholarPubMed
Druett, H. A., Henderson, D. W., Packman, L. P. & Peacock, S. (1953). The influence of particle size on respiratory infection with anthrax spores. J. Hyg., Camb., 51, 359.CrossRefGoogle ScholarPubMed
Druett, H. A. & May, K. R. (1952). A wind tunnel for the study of airborne infections. J. Hyg., Camb., 50, 69.CrossRefGoogle Scholar
Druett, H. A., Robinson, J. M., Henderson, D. W., Packman, L. P. & Peacock, S. (1956). The influence of aerosol particle size on infection of the guinea-pig with Pasteurella pestis. J. Hyg., Camb., 54, 37.CrossRefGoogle ScholarPubMed
Elberg, S. S. & Henderson, D. W. (1948). Respiratory pathogenicity of Brucella. J. infect. Dis. 82, 302.CrossRefGoogle ScholarPubMed
Harper, G. J. (1955). Brucella suis infection of guinea-pigs by the respiratory route. Brit. J. exp. Path. 36, 60.Google ScholarPubMed
Harper, G. J. & Morton, J. D. (1953). The respiratory retention of bacterial aerosols: experiments with radioactive spores. J. Hyg., Camb., 51, 372.CrossRefGoogle ScholarPubMed
Henderson, D. W. (1952). An apparatus for the study of airborne infection. J. Hyg., Camb., 50, 53.CrossRefGoogle Scholar
May, K. R. (1949). An improved spinning top homogeneous spray apparatus. J. appl. Phys. 20, 932.CrossRefGoogle Scholar
Peto, S. (1953). A dose-response equation for the invasion of micro-organisms. J. biometric Soc. 9, 320.CrossRefGoogle Scholar
Stamp, Lord (1947). The preservation of bacteria by drying. J. gen. Microbiol. 1, 251.CrossRefGoogle ScholarPubMed