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Studies on poliomyelitis virus: III. The use of ultra-violet light as an additional means of inactivation of formalinized vaccine

Published online by Cambridge University Press:  15 May 2009

J. W. F. Hampton  and
A. Polson
J. W. F. Hampton
Affiliation:
Laboratories of the Poliomyelitis Research Foundation, Johannesburg, and the Council for Scientific and Industrial Research and University of Capetown Virus Research Unit, University of Capetown
A. Polson
Affiliation:
Laboratories of the Poliomyelitis Research Foundation, Johannesburg, and the Council for Scientific and Industrial Research and University of Capetown Virus Research Unit, University of Capetown
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The inactivation rates of tissue-culture polio virus have been determined and these have been applied to the irradiation of formalinized vaccine, as an additional inactivation process, using a simple irradiator.

The antigenic potency of the vaccine was apparently unimpaired.

We wish to thank the late Prof. van den Ende for his keen interest and criticism; Dr H. Malherbe and his staff for carrying out many of the titrations; Dr P. D. Winter for co-operation in irradiating samples of vaccine, and Margaret Pakes for invaluable technical assistance.

Type
Research Article
Information
Journal of Hygiene , Volume 56 , Issue 2 , June 1958 , pp. 266 - 270
Copyright
Copyright © Cambridge University Press 1958

References

REFERENCES

Fogh, J. (1955). Proc. Soc. exp. Biol., N.Y., 89, 464.CrossRefGoogle Scholar
Gard, S. (1955). European Association Against Polio. 3rd Symposium.Google Scholar
Gard, S., Wesslen, T., Fagraeus, A., Svedmyr, A. & Olin, G. (1956). Arch. ges. Virusforsch. 6, 401.CrossRefGoogle Scholar
Hampton, J. W. F., Polson, A. & Selzer, Golda (1958). J. Hyg., Camb., 56, 260.CrossRefGoogle Scholar
Kasha, M. (1948). J. opt. Soc. Amer. 38, 929.CrossRefGoogle Scholar
Kelly, S. & Dalldorf, G. (1956). Amer. J. Hyg. 64, 243.Google Scholar
Lea, D. E. (1955). Actions of Radiations on Living Cells, 2nd ed. Cambridge University Press.Google Scholar
Mclaren, A. D. (1949). Advanc. Enzymol. 9, 75.Google Scholar
Salk, J. E., Youngner, J. S. & Ward, E. N. (1954). Amer. J. Hyg. 60, 214.Google Scholar
Taylor, A. R., Kay, W. W., Mclean, I. W., Oppenheimer, F. & Stimpert, F. D. (1957). J. Immunol. 78, 45.CrossRefGoogle Scholar
Taylor, A. R., Kay, W. W., Timm, E. A., Mclean, I. W., Oppenheimer, F. & Stimpert, F. D. (1956). Fed. Proc. 15, 617.Google Scholar
Taylor, A. R., Sharp, D. G., Beard, D., Finkelstein, H. & Beard, J. W. (1941). J. infect. Dis. 59, 224.CrossRefGoogle Scholar