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Statistical analysis of data bearing on the number of particles required to form a plaque

Published online by Cambridge University Press:  15 May 2009

J. G. Kalbfleisch  and
D. A. Sprott
J. G. Kalbfleisch
Affiliation:
University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
D. A. Sprott
Affiliation:
University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
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Summary

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Methods of statistical analysis are presented for one or more dilution series experiments where the quantity of interest is the number of virus particles required to infect a cell. These methods are illustrated on several data sets drawn from the literature. Data from seven series, which have been used to support a two-particle model in the literature, are here shown to reject such a model decisively, whereas fifteen other experiments are found to be in excellent agreement with a one-particle model.

Type
Research Article
Information
Journal of Hygiene , Volume 73 , Issue 1 , August 1974 , pp. 27 - 34
Copyright
Copyright © Cambridge University Press 1974

References

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